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362 related items for PubMed ID: 23259581

  • 1. Regulation of enhanced cerebrovascular expression of proinflammatory mediators in experimental subarachnoid hemorrhage via the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway.
    Maddahi A, Povlsen GK, Edvinsson L.
    J Neuroinflammation; 2012 Dec 21; 9():274. PubMed ID: 23259581
    [Abstract] [Full Text] [Related]

  • 2. Improvement in neurological outcome and abolition of cerebrovascular endothelin B and 5-hydroxytryptamine 1B receptor upregulation through mitogen-activated protein kinase kinase 1/2 inhibition after subarachnoid hemorrhage in rats.
    Larsen CC, Povlsen GK, Rasmussen MN, Edvinsson L.
    J Neurosurg; 2011 Apr 21; 114(4):1143-53. PubMed ID: 20597604
    [Abstract] [Full Text] [Related]

  • 3. Blockade of the MEK/ERK pathway with a raf inhibitor prevents activation of pro-inflammatory mediators in cerebral arteries and reduction in cerebral blood flow after subarachnoid hemorrhage in a rat model.
    Maddahi A, Ansar S, Chen Q, Edvinsson L.
    J Cereb Blood Flow Metab; 2011 Jan 21; 31(1):144-54. PubMed ID: 20424636
    [Abstract] [Full Text] [Related]

  • 4. Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway.
    Müller AH, Edwards AVG, Larsen MR, Nielsen J, Warfvinge K, Povlsen GK, Edvinsson L.
    J Mol Neurosci; 2017 Aug 21; 62(3-4):380-394. PubMed ID: 28741142
    [Abstract] [Full Text] [Related]

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  • 6. Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway.
    Maddahi A, Edvinsson L.
    J Neuroinflammation; 2010 Feb 26; 7():14. PubMed ID: 20187933
    [Abstract] [Full Text] [Related]

  • 7. ERK1/2 inhibition attenuates cerebral blood flow reduction and abolishes ET(B) and 5-HT(1B) receptor upregulation after subarachnoid hemorrhage in rat.
    Beg SA, Hansen-Schwartz JA, Vikman PJ, Xu CB, Edvinsson LI.
    J Cereb Blood Flow Metab; 2006 Jun 26; 26(6):846-56. PubMed ID: 16251886
    [Abstract] [Full Text] [Related]

  • 8. Subtype activation and interaction of protein kinase C and mitogen-activated protein kinase controlling receptor expression in cerebral arteries and microvessels after subarachnoid hemorrhage.
    Ansar S, Edvinsson L.
    Stroke; 2008 Jan 26; 39(1):185-90. PubMed ID: 18032736
    [Abstract] [Full Text] [Related]

  • 9. Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat.
    Maddahi A, Chen Q, Edvinsson L.
    BMC Neurosci; 2009 Jun 04; 10():56. PubMed ID: 19497125
    [Abstract] [Full Text] [Related]

  • 10. CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function.
    Edvinsson L, Povlsen GK, Ahnstedt H, Waldsee R.
    J Neuroinflammation; 2014 Dec 10; 11():207. PubMed ID: 25498987
    [Abstract] [Full Text] [Related]

  • 11. The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat.
    Maddahi A, Kruse LS, Chen QW, Edvinsson L.
    J Neuroinflammation; 2011 Aug 28; 8():107. PubMed ID: 21871121
    [Abstract] [Full Text] [Related]

  • 12. MEK1/2 inhibitor U0126 but not endothelin receptor antagonist clazosentan reduces upregulation of cerebrovascular contractile receptors and delayed cerebral ischemia, and improves outcome after subarachnoid hemorrhage in rats.
    Povlsen GK, Edvinsson L.
    J Cereb Blood Flow Metab; 2015 Feb 28; 35(2):329-37. PubMed ID: 25407271
    [Abstract] [Full Text] [Related]

  • 13. Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury.
    Zhong Y, Chen J, Chen J, Chen Y, Li L, Xie Y.
    J Neurochem; 2019 Oct 28; 151(2):166-184. PubMed ID: 31314915
    [Abstract] [Full Text] [Related]

  • 14. Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.
    Shao A, Wu H, Hong Y, Tu S, Sun X, Wu Q, Zhao Q, Zhang J, Sheng J.
    Mol Neurobiol; 2016 Jul 28; 53(5):3462-3476. PubMed ID: 26091790
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of cerebrovascular raf activation attenuates cerebral blood flow and prevents upregulation of contractile receptors after subarachnoid hemorrhage.
    Ansar S, Maddahi A, Edvinsson L.
    BMC Neurosci; 2011 Oct 27; 12():107. PubMed ID: 22032648
    [Abstract] [Full Text] [Related]

  • 16. Essential role for ERK mitogen-activated protein kinase in matrix metalloproteinase-9 regulation in rat cortical astrocytes.
    Arai K, Lee SR, Lo EH.
    Glia; 2003 Sep 27; 43(3):254-64. PubMed ID: 12898704
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of MEK/ERK 1/2 pathway reduces pro-inflammatory cytokine interleukin-1 expression in focal cerebral ischemia.
    Wang ZQ, Wu DC, Huang FP, Yang GY.
    Brain Res; 2004 Jan 16; 996(1):55-66. PubMed ID: 14670631
    [Abstract] [Full Text] [Related]

  • 18. Possible Role of Raf-1 Kinase in the Development of Cerebral Vasospasm and Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats.
    Zhang J, Xu X, Zhou D, Li H, You W, Wang Z, Chen G.
    Mol Neurobiol; 2015 Dec 16; 52(3):1527-1539. PubMed ID: 25367879
    [Abstract] [Full Text] [Related]

  • 19. MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats.
    Christensen ST, Johansson SE, Radziwon-Balicka A, Warfvinge K, Haanes KA, Edvinsson L.
    PLoS One; 2019 Dec 16; 14(4):e0215398. PubMed ID: 30978262
    [Abstract] [Full Text] [Related]

  • 20. Signal transduction in cerebral arteries after subarachnoid hemorrhage-a phosphoproteomic approach.
    Parker BL, Larsen MR, Edvinsson LI, Povlsen GK.
    J Cereb Blood Flow Metab; 2013 Aug 16; 33(8):1259-69. PubMed ID: 23715060
    [Abstract] [Full Text] [Related]

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