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Journal Abstract Search

125 related items for PubMed ID: 23266121

  • 1. Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold.
    Miyazaki M, Naito H, Sugimoto Y, Kawato H, Okayama T, Shimizu H, Miyazaki M, Kitagawa M, Seki T, Fukutake S, Aonuma M, Soga T.
    Bioorg Med Chem Lett; 2013 Feb 01; 23(3):728-32. PubMed ID: 23266121
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  • 5. Discovery, synthesis, and biological evaluation of orally active pyrrolidone derivatives as novel inhibitors of p53-MDM2 protein-protein interaction.
    Zhuang C, Miao Z, Zhu L, Dong G, Guo Z, Wang S, Zhang Y, Wu Y, Yao J, Sheng C, Zhang W.
    J Med Chem; 2012 Nov 26; 55(22):9630-42. PubMed ID: 23046248
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  • 6. Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction.
    Vaupel A, Bold G, De Pover A, Stachyra-Valat T, Lisztwan JH, Kallen J, Masuya K, Furet P.
    Bioorg Med Chem Lett; 2014 May 01; 24(9):2110-4. PubMed ID: 24704029
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  • 9. Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.
    Noguchi T, Oishi S, Honda K, Kondoh Y, Saito T, Kubo T, Kaneda M, Ohno H, Osada H, Fujii N.
    Bioorg Med Chem Lett; 2013 Jul 01; 23(13):3802-5. PubMed ID: 23726030
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  • 11. Discovery of 1-arylpyrrolidone derivatives as potent p53-MDM2 inhibitors based on molecule fusing strategy.
    Li J, Wu Y, Guo Z, Zhuang C, Yao J, Dong G, Yu Z, Min X, Wang S, Liu Y, Wu S, Zhu S, Sheng C, Miao Z, Zhang W.
    Bioorg Med Chem Lett; 2014 Jun 15; 24(12):2648-50. PubMed ID: 24813735
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  • 13. Novel inhibitors of the MDM2-p53 interaction featuring hydrogen bond acceptors as carboxylic acid isosteres.
    Gonzalez AZ, Li Z, Beck HP, Canon J, Chen A, Chow D, Duquette J, Eksterowicz J, Fox BM, Fu J, Huang X, Houze J, Jin L, Li Y, Ling Y, Lo MC, Long AM, McGee LR, McIntosh J, Oliner JD, Osgood T, Rew Y, Saiki AY, Shaffer P, Wortman S, Yakowec P, Yan X, Ye Q, Yu D, Zhao X, Zhou J, Olson SH, Sun D, Medina JC.
    J Med Chem; 2014 Apr 10; 57(7):2963-88. PubMed ID: 24601644
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  • 15. Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction. Part 2.
    Wang W, Lv D, Qiu N, Zhang L, Hu C, Hu Y.
    Bioorg Med Chem; 2013 Jun 01; 21(11):2886-94. PubMed ID: 23611770
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