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Journal Abstract Search
125 related items for PubMed ID: 23266121
21. Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2-tumor protein 53 protein-protein interaction. Allen JG, Bourbeau MP, Wohlhieter GE, Bartberger MD, Michelsen K, Hungate R, Gadwood RC, Gaston RD, Evans B, Mann LW, Matison ME, Schneider S, Huang X, Yu D, Andrews PS, Reichelt A, Long AM, Yakowec P, Yang EY, Lee TA, Oliner JD. J Med Chem; 2009 Nov 26; 52(22):7044-53. PubMed ID: 19856920 [Abstract] [Full Text] [Related]
22. Group-based QSAR and molecular dynamics mechanistic analysis revealing the mode of action of novel piperidinone derived protein-protein inhibitors of p53-MDM2. Goyal S, Grover S, Dhanjal JK, Tyagi C, Goyal M, Grover A. J Mol Graph Model; 2014 Jun 26; 51():64-72. PubMed ID: 24858256 [Abstract] [Full Text] [Related]
23. Investigation of the inhibitory mechanism of apomorphine against MDM2-p53 interaction. Ishiba H, Noguchi T, Shu K, Ohno H, Honda K, Kondoh Y, Osada H, Fujii N, Oishi S. Bioorg Med Chem Lett; 2017 Jun 01; 27(11):2571-2574. PubMed ID: 28400230 [Abstract] [Full Text] [Related]
24. The development of piperidinones as potent MDM2-P53 protein-protein interaction inhibitors for cancer therapy. Liao G, Yang D, Ma L, Li W, Hu L, Zeng L, Wu P, Duan L, Liu Z. Eur J Med Chem; 2018 Nov 05; 159():1-9. PubMed ID: 30253242 [Abstract] [Full Text] [Related]
25. Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy. Zhang Z, Ding Q, Liu JJ, Zhang J, Jiang N, Chu XJ, Bartkovitz D, Luk KC, Janson C, Tovar C, Filipovic ZM, Higgins B, Glenn K, Packman K, Vassilev LT, Graves B. Bioorg Med Chem; 2014 Aug 01; 22(15):4001-9. PubMed ID: 24997575 [Abstract] [Full Text] [Related]
32. Screening of medicinal plant phytochemicals as natural antagonists of p53-MDM2 interaction to reactivate p53 functioning. Riaz M, Ashfaq UA, Qasim M, Yasmeen E, Ul Qamar MT, Anwar F. Anticancer Drugs; 2017 Oct 01; 28(9):1032-1038. PubMed ID: 28723868 [Abstract] [Full Text] [Related]
33. Stereochemical studies of hexylitaconic acid, an inhibitor of p53-HDM2 interaction. Nakahashi A, Miura N, Monde K, Tsukamoto S. Bioorg Med Chem Lett; 2009 Jun 01; 19(11):3027-30. PubMed ID: 19414261 [Abstract] [Full Text] [Related]