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530 related items for PubMed ID: 23283967

  • 1. Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation.
    Vela L, Gonzalo O, Naval J, Marzo I.
    J Biol Chem; 2013 Feb 15; 288(7):4935-46. PubMed ID: 23283967
    [Abstract] [Full Text] [Related]

  • 2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
    [Abstract] [Full Text] [Related]

  • 3. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2006 Dec 18; 8(12):1348-58. PubMed ID: 17115033
    [Abstract] [Full Text] [Related]

  • 4. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T.
    J Biol Chem; 2011 Jan 07; 286(1):491-501. PubMed ID: 21041309
    [Abstract] [Full Text] [Related]

  • 5. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2015 Oct 07; 17(10):1270-81. PubMed ID: 26344567
    [Abstract] [Full Text] [Related]

  • 6. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM.
    Cell Death Dis; 2015 Apr 23; 6(4):e1735. PubMed ID: 25906158
    [Abstract] [Full Text] [Related]

  • 7. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 8. Synergistic induction of apoptosis by p53-inducible Bcl-2 family proteins Noxa and Puma.
    Nakajima W, Tanaka N.
    J Nippon Med Sch; 2007 Apr 16; 74(2):148-57. PubMed ID: 17507791
    [Abstract] [Full Text] [Related]

  • 9. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
    Kim H, Tu HC, Ren D, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Mol Cell; 2009 Nov 13; 36(3):487-99. PubMed ID: 19917256
    [Abstract] [Full Text] [Related]

  • 10. BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
    Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Science; 2010 Dec 03; 330(6009):1390-3. PubMed ID: 21127253
    [Abstract] [Full Text] [Related]

  • 11. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
    McKenzie MD, Jamieson E, Jansen ES, Scott CL, Huang DC, Bouillet P, Allison J, Kay TW, Strasser A, Thomas HE.
    Diabetes; 2010 Mar 03; 59(3):644-52. PubMed ID: 19959756
    [Abstract] [Full Text] [Related]

  • 12. Structural insight into BH3 domain binding of vaccinia virus antiapoptotic F1L.
    Campbell S, Thibault J, Mehta N, Colman PM, Barry M, Kvansakul M.
    J Virol; 2014 Aug 03; 88(15):8667-77. PubMed ID: 24850748
    [Abstract] [Full Text] [Related]

  • 13. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
    Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC.
    Science; 2007 Feb 09; 315(5813):856-9. PubMed ID: 17289999
    [Abstract] [Full Text] [Related]

  • 14. AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts.
    González-Gironès DM, Moncunill-Massaguer C, Iglesias-Serret D, Cosialls AM, Pérez-Perarnau A, Palmeri CM, Rubio-Patiño C, Villunger A, Pons G, Gil J.
    Apoptosis; 2013 Aug 09; 18(8):1008-16. PubMed ID: 23605481
    [Abstract] [Full Text] [Related]

  • 15. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
    Gillissen B, Essmann F, Hemmati PG, Richter A, Richter A, Oztop I, Chinnadurai G, Dörken B, Daniel PT.
    J Cell Biol; 2007 Nov 19; 179(4):701-15. PubMed ID: 18025305
    [Abstract] [Full Text] [Related]

  • 16. BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins.
    Weber A, Paschen SA, Heger K, Wilfling F, Frankenberg T, Bauerschmitt H, Seiffert BM, Kirschnek S, Wagner H, Häcker G.
    J Cell Biol; 2007 May 21; 177(4):625-36. PubMed ID: 17517961
    [Abstract] [Full Text] [Related]

  • 17. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ.
    Mol Cell; 2001 Sep 21; 8(3):705-11. PubMed ID: 11583631
    [Abstract] [Full Text] [Related]

  • 18. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K, O'Neill KL, Li J, Zhou W, Han N, Pang X, Wu W, Struble L, Borgstahl G, Liu Z, Zhang L, Luo X.
    Cell Res; 2019 Nov 21; 29(11):942-952. PubMed ID: 31551537
    [Abstract] [Full Text] [Related]

  • 19. The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.
    Gomez JA, Sun W, Gama V, Hajkova D, Yoshida T, Wu Z, Miyagi M, Pink JJ, Jackson MW, Danielpour D, Matsuyama S.
    Cancer Biol Ther; 2009 Sep 21; 8(18):1771-86. PubMed ID: 19657228
    [Abstract] [Full Text] [Related]

  • 20. Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.
    Miller AV, Hicks MA, Nakajima W, Richardson AC, Windle JJ, Harada H.
    PLoS One; 2013 Sep 21; 8(4):e60685. PubMed ID: 23577147
    [Abstract] [Full Text] [Related]

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