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Journal Abstract Search

274 related items for PubMed ID: 2328501

  • 1. Selectivity of rat and human glutathione S-transferases in activation of ethylene dibromide by glutathione conjugation and DNA binding and induction of unscheduled DNA synthesis in human hepatocytes.
    Cmarik JL, Inskeep PB, Meredith MJ, Meyer DJ, Ketterer B, Guengerich FP.
    Cancer Res; 1990 May 01; 50(9):2747-52. PubMed ID: 2328501
    [Abstract] [Full Text] [Related]

  • 2. Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione.
    Inskeep PB, Koga N, Cmarik JL, Guengerich FP.
    Cancer Res; 1986 Jun 01; 46(6):2839-44. PubMed ID: 2870801
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of oligonucleotides containing the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione at a single site.
    Kim MS, Guengerich FP.
    Chem Res Toxicol; 1997 Oct 01; 10(10):1133-43. PubMed ID: 9348436
    [Abstract] [Full Text] [Related]

  • 4. Formation of the DNA adduct S-[2-(N7-guanyl)ethyl]glutathione from ethylene dibromide: effects of modulation of glutathione and glutathione S-transferase levels and lack of a role for sulfation.
    Kim DH, Guengerich FP.
    Carcinogenesis; 1990 Mar 01; 11(3):419-24. PubMed ID: 2311185
    [Abstract] [Full Text] [Related]

  • 5. Rat hepatic glutathione S-transferase-mediated embryotoxic bioactivation of ethylene dibromide.
    Mitra A, Hilbelink DR, Dwornik JJ, Kulkarni A.
    Teratology; 1992 Nov 01; 46(5):439-46. PubMed ID: 1462248
    [Abstract] [Full Text] [Related]

  • 6. The use of human in vitro metabolic parameters to explore the risk assessment of hazardous compounds: the case of ethylene dibromide.
    Ploemen JP, Wormhoudt LW, Haenen GR, Oudshoorn MJ, Commandeur JN, Vermeulen NP, de Waziers I, Beaune PH, Watabe T, van Bladeren PJ.
    Toxicol Appl Pharmacol; 1997 Mar 01; 143(1):56-69. PubMed ID: 9073592
    [Abstract] [Full Text] [Related]

  • 7. Polymerase blockage and misincorporation of dNTPs opposite the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione.
    Kim MS, Guengerich FP.
    Chem Res Toxicol; 1998 Apr 01; 11(4):311-6. PubMed ID: 9548801
    [Abstract] [Full Text] [Related]

  • 8. Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats.
    Kim DH, Guengerich FP.
    Cancer Res; 1989 Nov 01; 49(21):5843-7. PubMed ID: 2790795
    [Abstract] [Full Text] [Related]

  • 9. Glutathione transferase theta 1-1-dependent metabolism of the water disinfection byproduct bromodichloromethane.
    Ross MK, Pegram RA.
    Chem Res Toxicol; 2003 Feb 01; 16(2):216-26. PubMed ID: 12588193
    [Abstract] [Full Text] [Related]

  • 10. Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
    Dirven HA, van Ommen B, van Bladeren PJ.
    Cancer Res; 1994 Dec 01; 54(23):6215-20. PubMed ID: 7954469
    [Abstract] [Full Text] [Related]

  • 11. Effect of butylated hydroxyanisole pretreatment on aflatoxin B1-DNA binding and aflatoxin B1-glutathione conjugation in isolated hepatocytes from rats.
    Jhee EC, Ho LL, Tsuji K, Gopalan P, Lotlikar PD.
    Cancer Res; 1989 Mar 15; 49(6):1357-60. PubMed ID: 2493978
    [Abstract] [Full Text] [Related]

  • 12. In vitro biotransformation and genotoxicity of the drinking water disinfection byproduct bromodichloromethane: DNA binding mediated by glutathione transferase theta 1-1.
    Ross MK, Pegram RA.
    Toxicol Appl Pharmacol; 2004 Mar 01; 195(2):166-81. PubMed ID: 14998683
    [Abstract] [Full Text] [Related]

  • 13. Screening and characterization of variant Theta-class glutathione transferases catalyzing the activation of ethylene dibromide to a mutagen.
    Josephy PD, Taylor PL, Vervaet G, Mannervik B.
    Environ Mol Mutagen; 2006 Dec 01; 47(9):657-65. PubMed ID: 16948056
    [Abstract] [Full Text] [Related]

  • 14. DNA-glutathione adducts derived from vic-dihaloalkanes: mechanisms of mutagenesis.
    Guengerich FP, Humphreys WG, Kim DH, Oida T, Cmarik JL.
    Princess Takamatsu Symp; 1990 Dec 01; 21():101-7. PubMed ID: 2134669
    [Abstract] [Full Text] [Related]

  • 15. Glutathione S-transferase-catalyzed conjugation of bioactivated aflatoxin B1 in rabbit lung and liver.
    Stewart RK, Serabjit-Singh CJ, Massey TE.
    Toxicol Appl Pharmacol; 1996 Oct 01; 140(2):499-507. PubMed ID: 8887467
    [Abstract] [Full Text] [Related]

  • 16. Induction of DNA repair in rat spermatocytes and hepatocytes by 1,2-dibromoethane: the role of glutathione conjugation.
    Working PK, Smith-Oliver T, White RD, Butterworth BE.
    Carcinogenesis; 1986 Mar 01; 7(3):467-72. PubMed ID: 3512119
    [Abstract] [Full Text] [Related]

  • 17. Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.
    Guengerich FP, Peterson LA, Cmarik JL, Koga N, Inskeep PB.
    Environ Health Perspect; 1987 Dec 01; 76():15-8. PubMed ID: 3329096
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of glutathione conjugation by glutathione analogues in the perfused rat liver. Effect of esterification on the potency of gamma-L-glutamyl-alpha-(D-2-aminoadipyl)-N-2-heptylamine.
    Ouwerkerk-Mahadevan S, Tirona RG, Ripping RA, Ploemen JH, van Bladeren PJ, Pang KS, van Boom JH, Mulder GJ.
    Drug Metab Dispos; 1997 Oct 01; 25(10):1137-43. PubMed ID: 9321516
    [Abstract] [Full Text] [Related]

  • 19. Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.
    Buetler TM, Bammler TK, Hayes JD, Eaton DL.
    Cancer Res; 1996 May 15; 56(10):2306-13. PubMed ID: 8625305
    [Abstract] [Full Text] [Related]

  • 20. Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases.
    Tang W, Borel AG, Abbott FS.
    Drug Metab Dispos; 1996 Apr 15; 24(4):436-46. PubMed ID: 8801059
    [Abstract] [Full Text] [Related]

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