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192 related items for PubMed ID: 23291634

  • 1. Ex vivo and in vivo investigations of the effects of extracts of Vernonia amygdalina, Carica papaya and Tapinanthus sessilifolius on digoxin transport and pharmacokinetics: assessing the significance on rat intestinal P-glycoprotein efflux.
    Oga EF, Sekine S, Horie T.
    Drug Metab Pharmacokinet; 2013; 28(4):314-20. PubMed ID: 23291634
    [Abstract] [Full Text] [Related]

  • 2. P-glycoprotein mediated efflux in Caco-2 cell monolayers: the influence of herbals on digoxin transport.
    Oga EF, Sekine S, Shitara Y, Horie T.
    J Ethnopharmacol; 2012 Dec 18; 144(3):612-7. PubMed ID: 23064285
    [Abstract] [Full Text] [Related]

  • 3. Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Yu XY, Lin SG, Zhou ZW, Chen X, Liang J, Liu PQ, Duan W, Chowbay B, Wen JY, Li CG, Zhou SF.
    Curr Drug Metab; 2007 May 18; 8(4):325-40. PubMed ID: 17504222
    [Abstract] [Full Text] [Related]

  • 4. Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats.
    Zhang H, Yao M, Morrison RA, Chong S.
    Arch Pharm Res; 2003 Sep 18; 26(9):768-72. PubMed ID: 14560928
    [Abstract] [Full Text] [Related]

  • 5. Montmorillonite-surfactant hybrid particles for modulating intestinal P-glycoprotein-mediated transport.
    Nielsen RB, Kahnt A, Dillen L, Wuyts K, Snoeys J, Nielsen UG, Holm R, Nielsen CU.
    Int J Pharm; 2019 Nov 25; 571():118696. PubMed ID: 31525443
    [Abstract] [Full Text] [Related]

  • 6. Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp.
    Li X, Hu J, Wang B, Sheng L, Liu Z, Yang S, Li Y.
    Toxicol Appl Pharmacol; 2014 Mar 01; 275(2):163-75. PubMed ID: 24380838
    [Abstract] [Full Text] [Related]

  • 7. P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.
    Yang JJ, Milton MN, Yu S, Liao M, Liu N, Wu JT, Gan L, Balani SK, Lee FW, Prakash S, Xia CQ.
    Drug Metab Lett; 2010 Dec 01; 4(4):201-12. PubMed ID: 20670210
    [Abstract] [Full Text] [Related]

  • 8. In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein.
    Liang Y, Zhou Y, Zhang J, Liu Y, Guan T, Wang Y, Xing L, Rao T, Zhou L, Hao K, Xie L, Wang GJ.
    Phytomedicine; 2013 Aug 15; 20(11):1030-8. PubMed ID: 23731657
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationships.
    Bai J, Zhao S, Fan X, Chen Y, Zou X, Hu M, Wang B, Jin J, Wang X, Hu J, Zhang D, Li Y.
    Toxicol Appl Pharmacol; 2019 Apr 15; 369():49-59. PubMed ID: 30790579
    [Abstract] [Full Text] [Related]

  • 10. Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers.
    Troutman MD, Thakker DR.
    Pharm Res; 2003 Aug 15; 20(8):1200-9. PubMed ID: 12948018
    [Abstract] [Full Text] [Related]

  • 11. Effects of Fostamatinib on the Pharmacokinetics of Digoxin (a P-Glycoprotein Substrate): Results From in Vitro and Phase I Clinical Studies.
    Martin P, Gillen M, Millson D, Oliver S, Brealey C, Elsby R, Baluom M, Lau D, Mant T.
    Clin Ther; 2015 Dec 01; 37(12):2811-22. PubMed ID: 26514315
    [Abstract] [Full Text] [Related]

  • 12. P-gp is involved in the intestinal absorption and biliary excretion of afatinib in vitro and in rats.
    Zhang Y, Wang C, Liu Z, Meng Q, Huo X, Liu Q, Sun P, Yang X, Sun H, Ma X, Liu K.
    Pharmacol Rep; 2018 Apr 01; 70(2):243-250. PubMed ID: 29475007
    [Abstract] [Full Text] [Related]

  • 13. Species difference in intestinal absorption mechanism of etoposide and digoxin between cynomolgus monkey and rat.
    Nishimura T, Kato Y, Amano N, Ono M, Kubo Y, Kimura Y, Fujita H, Tsuji A.
    Pharm Res; 2008 Nov 01; 25(11):2467-76. PubMed ID: 18626752
    [Abstract] [Full Text] [Related]

  • 14. Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells.
    Zhang S, Morris ME.
    Pharm Res; 2003 Aug 01; 20(8):1184-91. PubMed ID: 12948016
    [Abstract] [Full Text] [Related]

  • 15. 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.
    Zhang J, Zhou F, Wu X, Gu Y, Ai H, Zheng Y, Li Y, Zhang X, Hao G, Sun J, Peng Y, Wang G.
    Drug Metab Dispos; 2010 Dec 01; 38(12):2179-87. PubMed ID: 20837659
    [Abstract] [Full Text] [Related]

  • 16. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption.
    Yoshitomo A, Asano S, Hozuki S, Tamemoto Y, Shibata Y, Hashimoto N, Takahashi K, Sasaki Y, Ozawa N, Kageyama M, Iijima T, Kazuki Y, Sato H, Hisaka A.
    Drug Metab Dispos; 2023 Mar 01; 51(3):318-328. PubMed ID: 36810197
    [Abstract] [Full Text] [Related]

  • 17. P-glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: ex vivo and in vivo studies.
    Rocha-Pereira C, Ghanem CI, Silva R, Casanova AG, Duarte-Araújo M, Gonçalves-Monteiro S, Sousa E, Bastos ML, Remião F.
    Toxicol Appl Pharmacol; 2020 Jan 01; 386():114832. PubMed ID: 31756430
    [Abstract] [Full Text] [Related]

  • 18. Quantitative prediction of P-glycoprotein-mediated drug-drug interactions and intestinal absorption using humanized mice.
    Miyake T, Tsutsui H, Haraya K, Tachibana T, Morimoto K, Takehara S, Ayabe M, Kobayashi K, Kazuki Y.
    Br J Pharmacol; 2021 Nov 01; 178(21):4335-4351. PubMed ID: 34232502
    [Abstract] [Full Text] [Related]

  • 19. Effect of green tea catechins on the pharmacokinetics of digoxin in humans.
    Kim TE, Shin KH, Park JE, Kim MG, Yun YM, Choi DH, Kwon KJ, Lee J.
    Drug Des Devel Ther; 2018 Nov 01; 12():2139-2147. PubMed ID: 30022812
    [Abstract] [Full Text] [Related]

  • 20. Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P-gp Inhibition.
    Chu X, Galetin A, Zamek-Gliszczynski MJ, Zhang L, Tweedie DJ, International Transporter Consortium.
    Clin Pharmacol Ther; 2018 Nov 01; 104(5):788-792. PubMed ID: 30238965
    [No Abstract] [Full Text] [Related]

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