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Journal Abstract Search


166 related items for PubMed ID: 23322732

  • 1. Balanced Tiam1-rac1 and RhoA drives proliferation and invasion of pancreatic cancer cells.
    Guo X, Wang M, Jiang J, Xie C, Peng F, Li X, Tian R, Qin R.
    Mol Cancer Res; 2013 Mar; 11(3):230-9. PubMed ID: 23322732
    [Abstract] [Full Text] [Related]

  • 2. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P, Huynh-Do U.
    Cell Signal; 2014 Mar; 26(3):483-91. PubMed ID: 24308970
    [Abstract] [Full Text] [Related]

  • 3. Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration.
    Bourguignon LY, Zhu H, Shao L, Chen YW.
    J Cell Biol; 2000 Jul 10; 150(1):177-91. PubMed ID: 10893266
    [Abstract] [Full Text] [Related]

  • 4. Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions.
    Guillemot L, Paschoud S, Jond L, Foglia A, Citi S.
    Mol Biol Cell; 2008 Oct 10; 19(10):4442-53. PubMed ID: 18653465
    [Abstract] [Full Text] [Related]

  • 5. Integrin alpha 6 beta 4 promotes migration, invasion through Tiam1 upregulation, and subsequent Rac activation.
    Cruz-Monserrate Z, O'Connor KL.
    Neoplasia; 2008 May 10; 10(5):408-17. PubMed ID: 18472958
    [Abstract] [Full Text] [Related]

  • 6. Tiam1 methylation by NSD2 promotes Rac1 signaling activation and colon cancer metastasis.
    Song D, Hu F, Huang C, Lan J, She X, Zhao C, Wu H, Liu A, Wu Q, Chen Y, Luo X, Feng Y, Yang X, Xu C, Hu J, Wang G.
    Proc Natl Acad Sci U S A; 2023 Dec 26; 120(52):e2305684120. PubMed ID: 38113258
    [Abstract] [Full Text] [Related]

  • 7. Tiam1 promotes thyroid carcinoma metastasis by modulating EMT via Wnt/β-catenin signaling.
    Liu L, Wu B, Cai H, Li D, Ma Y, Zhu X, Lv Z, Fan Y, Zhang X.
    Exp Cell Res; 2018 Jan 15; 362(2):532-540. PubMed ID: 29277502
    [Abstract] [Full Text] [Related]

  • 8. Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphology.
    Matsuo N, Terao M, Nabeshima Y, Hoshino M.
    Mol Cell Neurosci; 2003 Sep 15; 24(1):69-81. PubMed ID: 14550769
    [Abstract] [Full Text] [Related]

  • 9. The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.
    Xu Z, Gakhar L, Bain FE, Spies M, Fuentes EJ.
    J Biol Chem; 2017 Oct 27; 292(43):17777-17793. PubMed ID: 28882897
    [Abstract] [Full Text] [Related]

  • 10. Clinical value of Tiam1-Rac1 signaling in primary gallbladder carcinoma.
    Du X, Wang S, Lu J, Wang Q, Song N, Yang T, Dong R, Zang L, Yang Y, Wu T, Wang C.
    Med Oncol; 2012 Sep 27; 29(3):1873-8. PubMed ID: 21853342
    [Abstract] [Full Text] [Related]

  • 11. ROCK1 feedback regulation of the upstream small GTPase RhoA.
    Tang AT, Campbell WB, Nithipatikom K.
    Cell Signal; 2012 Jul 27; 24(7):1375-80. PubMed ID: 22430126
    [Abstract] [Full Text] [Related]

  • 12. An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis.
    Zhu G, Fan Z, Ding M, Zhang H, Mu L, Ding Y, Zhang Y, Jia B, Chen L, Chang Z, Wu W.
    Oncogene; 2015 Dec 03; 34(49):5971-82. PubMed ID: 25746002
    [Abstract] [Full Text] [Related]

  • 13. Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons.
    Čajánek L, Ganji RS, Henriques-Oliveira C, Theofilopoulos S, Koník P, Bryja V, Arenas E.
    Mol Cell Biol; 2013 Jan 03; 33(1):59-70. PubMed ID: 23109420
    [Abstract] [Full Text] [Related]

  • 14. Tiam1 is recruited to β1-integrin complexes by 14-3-3ζ where it mediates integrin-induced Rac1 activation and motility.
    O'Toole TE, Bialkowska K, Li X, Fox JE.
    J Cell Physiol; 2011 Nov 03; 226(11):2965-78. PubMed ID: 21302295
    [Abstract] [Full Text] [Related]

  • 15. Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.
    Servitja JM, Marinissen MJ, Sodhi A, Bustelo XR, Gutkind JS.
    J Biol Chem; 2003 Sep 05; 278(36):34339-46. PubMed ID: 12810717
    [Abstract] [Full Text] [Related]

  • 16. 5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation.
    Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M.
    Cancer Sci; 2014 Mar 05; 105(3):290-6. PubMed ID: 24350867
    [Abstract] [Full Text] [Related]

  • 17. Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma.
    Yang W, Lv S, Liu X, Liu H, Yang W, Hu F.
    Jpn J Clin Oncol; 2010 Nov 05; 40(11):1053-9. PubMed ID: 20522449
    [Abstract] [Full Text] [Related]

  • 18. Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.
    Hofbauer SW, Krenn PW, Ganghammer S, Asslaber D, Pichler U, Oberascher K, Henschler R, Wallner M, Kerschbaum H, Greil R, Hartmann TN.
    Blood; 2014 Apr 03; 123(14):2181-8. PubMed ID: 24501217
    [Abstract] [Full Text] [Related]

  • 19. The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration.
    Saxena M, Dykes SS, Malyarchuk S, Wang AE, Cardelli JA, Pruitt K.
    Oncogene; 2015 Jan 08; 34(2):188-98. PubMed ID: 24362520
    [Abstract] [Full Text] [Related]

  • 20. Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components.
    Fleming IN, Gray A, Downes CP.
    Biochem J; 2000 Oct 01; 351(Pt 1):173-82. PubMed ID: 10998360
    [Abstract] [Full Text] [Related]


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