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Journal Abstract Search

48 related items for PubMed ID: 23343186

  • 1. [(3)H]metyrapol and 4-[(131)i]iodometomidate label overlapping, but not identical, binding sites on rat adrenal membranes.
    Berger ML, Hammerschmidt F, Qian R, Hahner S, Schirbel A, Stichelberger M, Schibli R, Yu J, Arion VB, Woschek A, Öhler E, Zolle IM.
    Mol Pharm; 2013 Mar 04; 10(3):1119-30. PubMed ID: 23343186
    [Abstract] [Full Text] [Related]

  • 2. New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
    Zolle IM, Berger ML, Hammerschmidt F, Hahner S, Schirbel A, Peric-Simov B.
    J Med Chem; 2008 Apr 10; 51(7):2244-53. PubMed ID: 18348518
    [Abstract] [Full Text] [Related]

  • 3. Stereoselective reductive metabolism of metyrapone and inhibitory activity of metyrapone metabolites, metyrapol enantiomers, on steroid 11 beta-hydroxylase in the rat.
    Nagamine S, Horisaka E, Fukuyama Y, Maetani K, Matsuzawa R, Iwakawa S, Asada S.
    Biol Pharm Bull; 1997 Feb 10; 20(2):188-92. PubMed ID: 9057984
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity relationship of etomidate derivatives at the GABA(A) receptor: Comparison with binding to 11beta-hydroxylase.
    Atucha E, Hammerschmidt F, Zolle I, Sieghart W, Berger ML.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4284-7. PubMed ID: 19497738
    [Abstract] [Full Text] [Related]

  • 5. Steroid 11beta-hydroxylation in beef adrenal cortex mitochondria. Binding affinity and capacity of specific (14C)steroids and for (3H)metyrapol, an inhibitor of the 11beta-hydroxylation reaction.
    Satre M, Vignais PV.
    Biochemistry; 1974 May 07; 13(10):2201-9. PubMed ID: 4826891
    [No Abstract] [Full Text] [Related]

  • 6. ( 3 H)metyrapol as a tool for studies of interactions of deoxycorticosterone with adrenal cortex mitochondria.
    Satre M, Lunardi J, Vignais PV.
    FEBS Lett; 1972 Oct 01; 26(1):193-6. PubMed ID: 4636729
    [No Abstract] [Full Text] [Related]

  • 7. 2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels.
    Husain SS, Ziebell MR, Ruesch D, Hong F, Arevalo E, Kosterlitz JA, Olsen RW, Forman SA, Cohen JB, Miller KW.
    J Med Chem; 2003 Mar 27; 46(7):1257-65. PubMed ID: 12646036
    [Abstract] [Full Text] [Related]

  • 8. In vitro and in vivo primate evaluation of carbon-11-etomidate and carbon-11-metomidate as potential tracers for PET imaging of the adrenal cortex and its tumors.
    Bergström M, Bonasera TA, Lu L, Bergström E, Backlin C, Juhlin C, Långström B.
    J Nucl Med; 1998 Jun 27; 39(6):982-9. PubMed ID: 9627330
    [Abstract] [Full Text] [Related]

  • 9. Sedative-hypnotic Binding to 11β-hydroxylase.
    Pejo E, Zhou X, Husain SS, Raines DE.
    Anesthesiology; 2016 Nov 27; 125(5):943-951. PubMed ID: 27541316
    [Abstract] [Full Text] [Related]

  • 10. Metabolism of metyrapone. III. Formation of an alpha-pyridone metabolite by rat hepatic soluble enzymes.
    Damani LA, Crooks PA, Cowan DA.
    Drug Metab Dispos; 1981 Nov 27; 9(3):270-3. PubMed ID: 6113939
    [Abstract] [Full Text] [Related]

  • 11. Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone.
    Rigel DF, Fu F, Beil M, Hu CW, Liang G, Jeng AY.
    J Pharmacol Exp Ther; 2010 Jul 27; 334(1):232-43. PubMed ID: 20354176
    [Abstract] [Full Text] [Related]

  • 12. Carboetomidate: an analog of etomidate that interacts weakly with 11β-hydroxylase.
    Shanmugasundararaj S, Zhou X, Neunzig J, Bernhardt R, Cotten JF, Ge R, Miller KW, Raines DE.
    Anesth Analg; 2013 Jun 27; 116(6):1249-56. PubMed ID: 23492967
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of metyrapone. 2-Chromatographic and mass spectral properties of the N-oxides of metyrapone and metyrapol.
    Damani LA, Crooks PA, Cowan DA.
    Biomed Mass Spectrom; 1981 Jun 27; 8(6):270-7. PubMed ID: 7260343
    [Abstract] [Full Text] [Related]

  • 14. Alteration of the inhibitory effect of metyrapone by reduction to metyrapol during the metabolism of methacetin in vivo in mice.
    Maser E, Legrum W.
    Naunyn Schmiedebergs Arch Pharmacol; 1985 Nov 27; 331(2-3):283-9. PubMed ID: 3937061
    [Abstract] [Full Text] [Related]

  • 15. Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells.
    Lamberts SW, Bons EG, Bruining HA, de Jong FH.
    J Pharmacol Exp Ther; 1987 Jan 27; 240(1):259-64. PubMed ID: 3027305
    [Abstract] [Full Text] [Related]

  • 16. New inhibitors of steroid 11beta-hydroxylase. Structure--activity relationship studies of metyrapone-like compounds.
    Napoli JL, Counsell RE.
    J Med Chem; 1977 Jun 27; 20(6):762-6. PubMed ID: 874952
    [Abstract] [Full Text] [Related]

  • 17. Dimethoxy-etomidate: A Nonhypnotic Etomidate Analog that Potently Inhibits Steroidogenesis.
    McGrath M, Ma C, Raines DE.
    J Pharmacol Exp Ther; 2018 Feb 27; 364(2):229-237. PubMed ID: 29203576
    [Abstract] [Full Text] [Related]

  • 18. The urinary metabolic profile of metyrapone in the rat. Identification of two novel isomeric metyrapol N-oxide metabolites.
    Usansky JI, Damani LA.
    Drug Metab Dispos; 1992 Feb 27; 20(1):64-9. PubMed ID: 1346999
    [Abstract] [Full Text] [Related]

  • 19. Assay of metyrapone, metyrapol and the isomeric mono-N-oxides of metyrapone in biological fluids by high-performance liquid chromatography.
    Usansky JI, Damani LA.
    J Chromatogr; 1991 Feb 15; 563(2):283-98. PubMed ID: 2055992
    [Abstract] [Full Text] [Related]

  • 20. Pharmacological characterization of a novel nonpeptide antagonist radioligand, (+/-)-N-[2-methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine ([3H]SN003) for corticotropin-releasing factor1 receptors.
    Zhang G, Huang N, Li YW, Qi X, Marshall AP, Yan XX, Hill G, Rominger C, Prakash SR, Bakthavatchalam R, Rominger DH, Gilligan PJ, Zaczek R.
    J Pharmacol Exp Ther; 2003 Apr 15; 305(1):57-69. PubMed ID: 12649353
    [Abstract] [Full Text] [Related]

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