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Journal Abstract Search


1241 related items for PubMed ID: 23344663

  • 21. γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.
    Séveno C, Loussouarn D, Bréchet S, Campone M, Juin P, Barillé-Nion S.
    Breast Cancer Res; 2012 Jun 15; 14(3):R96. PubMed ID: 22703841
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  • 22. Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.
    Wesarg E, Hoffarth S, Wiewrodt R, Kröll M, Biesterfeld S, Huber C, Schuler M.
    Int J Cancer; 2007 Dec 01; 121(11):2387-94. PubMed ID: 17688235
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  • 23. Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737.
    Oakes SR, Vaillant F, Lim E, Lee L, Breslin K, Feleppa F, Deb S, Ritchie ME, Takano E, Ward T, Fox SB, Generali D, Smyth GK, Strasser A, Huang DC, Visvader JE, Lindeman GJ.
    Proc Natl Acad Sci U S A; 2012 Feb 21; 109(8):2766-71. PubMed ID: 21768359
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  • 24. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer.
    Nakajima W, Hicks MA, Tanaka N, Krystal GW, Harada H.
    Cell Death Dis; 2014 Feb 13; 5(2):e1052. PubMed ID: 24525728
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  • 25. 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
    Lin X, Morgan-Lappe S, Huang X, Li L, Zakula DM, Vernetti LA, Fesik SW, Shen Y.
    Oncogene; 2007 Jun 07; 26(27):3972-9. PubMed ID: 17173063
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  • 27. Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737.
    Okumura K, Huang S, Sinicrope FA.
    Clin Cancer Res; 2008 Dec 15; 14(24):8132-42. PubMed ID: 19088028
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  • 28. Mcl-1 is an important therapeutic target for oral squamous cell carcinomas.
    Maji S, Samal SK, Pattanaik L, Panda S, Quinn BA, Das SK, Sarkar D, Pellecchia M, Fisher PB, Dash R.
    Oncotarget; 2015 Jun 30; 6(18):16623-37. PubMed ID: 26009874
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  • 30. Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia.
    Iacovelli S, Ricciardi MR, Allegretti M, Mirabilii S, Licchetta R, Bergamo P, Rinaldo C, Zeuner A, Foà R, Milella M, McCubrey JA, Martelli AM, Tafuri A.
    Oncotarget; 2015 Oct 13; 6(31):32089-103. PubMed ID: 26392332
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  • 31. Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells.
    Pandey MK, Gowda K, Doi K, Sharma AK, Wang HG, Amin S.
    PLoS One; 2013 Oct 13; 8(11):e78570. PubMed ID: 24223823
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  • 33. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S, Dai Y, Harada H, Dent P, Grant S.
    Cancer Res; 2007 Jan 15; 67(2):782-91. PubMed ID: 17234790
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  • 36. Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1.
    Zall H, Weber A, Besch R, Zantl N, Häcker G.
    Mol Cancer; 2010 Jun 24; 9():164. PubMed ID: 20576107
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  • 37. Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1.
    Zhang S, Li G, Ma X, Wang Y, Liu G, Feng L, Zhao Y, Zhang G, Wu Y, Ye X, Qin B, Lu J.
    Cell Signal; 2012 Sep 24; 24(9):1803-9. PubMed ID: 22609455
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  • 40. Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells.
    Simonin K, Brotin E, Dufort S, Dutoit S, Goux D, N'diaye M, Denoyelle C, Gauduchon P, Poulain L.
    Mol Cancer Ther; 2009 Nov 24; 8(11):3162-70. PubMed ID: 19887550
    [Abstract] [Full Text] [Related]


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