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Journal Abstract Search

203 related items for PubMed ID: 2338944

  • 1. Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3'-azido-3'-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM).
    Fridland A, Connelly MC, Ashmun R.
    Mol Pharmacol; 1990 May; 37(5):665-70. PubMed ID: 2338944
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  • 2. Cytotoxicity of 3'-azido-3'-deoxythymidine correlates with 3'-azidothymidine-5'-monophosphate (AZTMP) levels, whereas anti-human immunodeficiency virus (HIV) activity correlates with 3'-azidothymidine-5'-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells.
    Törnevik Y, Ullman B, Balzarini J, Wahren B, Eriksson S.
    Biochem Pharmacol; 1995 Mar 15; 49(6):829-37. PubMed ID: 7702641
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  • 3. 2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine.
    Törnevik Y, Eriksson S.
    Mol Pharmacol; 1990 Aug 15; 38(2):237-43. PubMed ID: 2166904
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  • 4. Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).
    Balzarini J, Naesens L, Aquaro S, Knispel T, Perno C, De Clercq E, Meier C.
    Mol Pharmacol; 1999 Dec 15; 56(6):1354-61. PubMed ID: 10570065
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  • 5. 3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8.
    Darnowski JW, Goulette FA.
    Biochem Pharmacol; 1994 Nov 01; 48(9):1797-805. PubMed ID: 7980649
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  • 6. 3'-Azido-3'-deoxythymidine-(5')-tetraphospho-(5')-adenosine, the product of ATP-mediated excision of chain-terminating AZTMP, is a potent chain-terminating substrate for HIV-1 reverse transcriptase.
    Dharmasena S, Pongracz Z, Arnold E, Sarafianos SG, Parniak MA.
    Biochemistry; 2007 Jan 23; 46(3):828-36. PubMed ID: 17223704
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  • 7. The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.
    Boyer PL, Sarafianos SG, Arnold E, Hughes SH.
    J Virol; 2002 Apr 23; 76(7):3248-56. PubMed ID: 11884549
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  • 10. Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells.
    Frick LW, Nelson DJ, St Clair MH, Furman PA, Krenitsky TA.
    Biochem Biophys Res Commun; 1988 Jul 15; 154(1):124-9. PubMed ID: 3164996
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  • 11. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
    Kerr SG, Anderson KS.
    Biochemistry; 1997 Nov 18; 36(46):14064-70. PubMed ID: 9369478
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  • 14. Mutants from V79 fibroblasts exhibiting hypersensitivity to aphidicolin and 3'-azido-3'-deoxythymidine.
    Liu PK, Norwood TH.
    Somat Cell Mol Genet; 1991 Jan 18; 17(1):1-13. PubMed ID: 1900132
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  • 17. Metabolism of 3'-azido-3'-deoxythymidine (AZT) in human placental trophoblasts and Hofbauer cells.
    Qian M, Bui T, Ho RJ, Unadkat JD.
    Biochem Pharmacol; 1994 Jul 19; 48(2):383-9. PubMed ID: 8053935
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  • 18. Effects of 3'-azido-3'-deoxythymidine metabolites on simian virus 40 origin-dependent replication and heteroduplex repair in HeLa cell extracts.
    Bebenek K, Thomas DC, Roberts JD, Eckstein F, Kunkel TA.
    Mol Pharmacol; 1993 Jan 19; 43(1):57-63. PubMed ID: 8380884
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  • 19. Effect of gallium on DNA synthesis by human T-cell lymphoblasts.
    Hedley DW, Tripp EH, Slowiaczek P, Mann GJ.
    Cancer Res; 1988 Jun 01; 48(11):3014-8. PubMed ID: 3259158
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  • 20. Evidence of in vitro development of drug resistance to azidothymidine in T-lymphocytic leukemia cell lines (Jurkat E6-1/AZT-100) and in pediatric patients with HIV-1 infection.
    Avramis VI, Kwock R, Solorzano MM, Gomperts E.
    J Acquir Immune Defic Syndr (1988); 1993 Dec 01; 6(12):1287-96. PubMed ID: 8254464
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