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Journal Abstract Search


271 related items for PubMed ID: 23413029

  • 1. Prolyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathway.
    Song D, Li LS, Heaton-Johnson KJ, Arsenault PR, Master SR, Lee FS.
    J Biol Chem; 2013 Apr 05; 288(14):9662-9674. PubMed ID: 23413029
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  • 2. Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing.
    Song D, Li LS, Arsenault PR, Tan Q, Bigham AW, Heaton-Johnson KJ, Master SR, Lee FS.
    J Biol Chem; 2014 May 23; 289(21):14656-65. PubMed ID: 24711448
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  • 3. Identification of Small-Molecule PHD2 Zinc Finger Inhibitors that Activate Hypoxia Inducible Factor.
    Arsenault PR, Song D, Bergkamp M, Ravaschiere AM, Navalsky BE, Lieberman PM, Lee FS.
    Chembiochem; 2016 Dec 14; 17(24):2316-2323. PubMed ID: 27770548
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  • 6. Inhibition of the catalytic activity of hypoxia-inducible factor-1alpha-prolyl-hydroxylase 2 by a MYND-type zinc finger.
    Choi KO, Lee T, Lee N, Kim JH, Yang EG, Yoon JM, Kim JH, Lee TG, Park H.
    Mol Pharmacol; 2005 Dec 14; 68(6):1803-9. PubMed ID: 16155211
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  • 8. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, Jelkmann W, Jaakkola P, Metzen E.
    Biochem J; 2004 Aug 01; 381(Pt 3):761-7. PubMed ID: 15104534
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  • 9. Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.
    Spinella F, Rosanò L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, Bagnato A.
    PLoS One; 2010 Jun 21; 5(6):e11241. PubMed ID: 20574527
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  • 10. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
    Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, Ratcliffe PJ, Gleadle JM.
    J Biol Chem; 2004 Sep 10; 279(37):38458-65. PubMed ID: 15247232
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  • 12. Hypoxia-inducible factor prolyl-hydroxylase 2 senses high-salt intake to increase hypoxia inducible factor 1alpha levels in the renal medulla.
    Wang Z, Zhu Q, Xia M, Li PL, Hinton SJ, Li N.
    Hypertension; 2010 May 10; 55(5):1129-36. PubMed ID: 20308610
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  • 13. Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
    Kageyama Y, Koshiji M, To KK, Tian YM, Ratcliffe PJ, Huang LE.
    FASEB J; 2004 Jun 10; 18(9):1028-30. PubMed ID: 15084514
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  • 14. Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.
    Berchner-Pfannschmidt U, Yamac H, Trinidad B, Fandrey J.
    J Biol Chem; 2007 Jan 19; 282(3):1788-96. PubMed ID: 17060326
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  • 15. Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
    Pientka FK, Hu J, Schindler SG, Brix B, Thiel A, Jöhren O, Fandrey J, Berchner-Pfannschmidt U, Depping R.
    J Cell Sci; 2012 Nov 01; 125(Pt 21):5168-76. PubMed ID: 22946054
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  • 16. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
    Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ.
    J Biol Chem; 2004 Oct 08; 279(41):42719-25. PubMed ID: 15302861
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  • 17. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
    Berra E, Benizri E, Ginouvès A, Volmat V, Roux D, Pouysségur J.
    EMBO J; 2003 Aug 15; 22(16):4082-90. PubMed ID: 12912907
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  • 18. The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
    Barth S, Nesper J, Hasgall PA, Wirthner R, Nytko KJ, Edlich F, Katschinski DM, Stiehl DP, Wenger RH, Camenisch G.
    Mol Cell Biol; 2007 May 15; 27(10):3758-68. PubMed ID: 17353276
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  • 19. Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
    Hewitson KS, Schofield CJ, Ratcliffe PJ.
    Methods Enzymol; 2007 May 15; 435():25-42. PubMed ID: 17998047
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  • 20. Assays to Study Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (PHD2), a Key Human Oxygen Sensing Protein.
    Chan YY, Mbenza NM, Chan MC, Leung IKH.
    Methods Mol Biol; 2023 May 15; 2648():187-206. PubMed ID: 37039992
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