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Journal Abstract Search

376 related items for PubMed ID: 23416158

  • 1. Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma.
    Sharma A, Madhunapantula SV, Gowda R, Berg A, Neves RI, Robertson GP.
    Am J Pathol; 2013 Apr; 182(4):1151-62. PubMed ID: 23416158
    [Abstract] [Full Text] [Related]

  • 2. HI-511 overcomes melanoma drug resistance via targeting AURKB and BRAF V600E.
    Chang X, Zhang T, Wang Q, Rathore MG, Reddy K, Chen H, Shin SH, Ma WY, Bode AM, Dong Z.
    Theranostics; 2020 Apr; 10(21):9721-9740. PubMed ID: 32863956
    [Abstract] [Full Text] [Related]

  • 3. Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma.
    Jalili A, Wagner C, Pashenkov M, Pathria G, Mertz KD, Widlund HR, Lupien M, Brunet JP, Golub TR, Stingl G, Fisher DE, Ramaswamy S, Wagner SN.
    J Natl Cancer Inst; 2012 Nov 07; 104(21):1673-9. PubMed ID: 22997239
    [Abstract] [Full Text] [Related]

  • 4. Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases.
    Sharma A, Tran MA, Liang S, Sharma AK, Amin S, Smith CD, Dong C, Robertson GP.
    Cancer Res; 2006 Aug 15; 66(16):8200-9. PubMed ID: 16912199
    [Abstract] [Full Text] [Related]

  • 5. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
    Nazarian R, Shi H, Wang Q, Kong X, Koya RC, Lee H, Chen Z, Lee MK, Attar N, Sazegar H, Chodon T, Nelson SF, McArthur G, Sosman JA, Ribas A, Lo RS.
    Nature; 2010 Dec 16; 468(7326):973-7. PubMed ID: 21107323
    [Abstract] [Full Text] [Related]

  • 6. Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development.
    Cheung M, Sharma A, Madhunapantula SV, Robertson GP.
    Cancer Res; 2008 May 01; 68(9):3429-39. PubMed ID: 18451171
    [Abstract] [Full Text] [Related]

  • 7. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.
    Cesi G, Walbrecq G, Zimmer A, Kreis S, Haan C.
    Mol Cancer; 2017 Jun 08; 16(1):102. PubMed ID: 28595656
    [Abstract] [Full Text] [Related]

  • 8. Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.
    Bonet C, Giuliano S, Ohanna M, Bille K, Allegra M, Lacour JP, Bahadoran P, Rocchi S, Ballotti R, Bertolotto C.
    J Biol Chem; 2012 Aug 24; 287(35):29887-98. PubMed ID: 22767597
    [Abstract] [Full Text] [Related]

  • 9. Antitumor efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression.
    Hoeflich KP, Herter S, Tien J, Wong L, Berry L, Chan J, O'Brien C, Modrusan Z, Seshagiri S, Lackner M, Stern H, Choo E, Murray L, Friedman LS, Belvin M.
    Cancer Res; 2009 Apr 01; 69(7):3042-51. PubMed ID: 19276360
    [Abstract] [Full Text] [Related]

  • 10. Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth.
    Hao H, Muniz-Medina VM, Mehta H, Thomas NE, Khazak V, Der CJ, Shields JM.
    Mol Cancer Ther; 2007 Aug 01; 6(8):2220-9. PubMed ID: 17699719
    [Abstract] [Full Text] [Related]

  • 11. Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.
    Tran MA, Gowda R, Sharma A, Park EJ, Adair J, Kester M, Smith NB, Robertson GP.
    Cancer Res; 2008 Sep 15; 68(18):7638-49. PubMed ID: 18794153
    [Abstract] [Full Text] [Related]

  • 12. BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB.
    McNeal AS, Belote RL, Zeng H, Urquijo M, Barker K, Torres R, Curtin M, Shain AH, Andtbacka RH, Holmen S, Lum DH, McCalmont TH, VanBrocklin MW, Grossman D, Wei ML, Lang UE, Judson-Torres RL.
    Elife; 2021 Nov 23; 10():. PubMed ID: 34812139
    [Abstract] [Full Text] [Related]

  • 13. Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway.
    Siwak DR, Shishodia S, Aggarwal BB, Kurzrock R.
    Cancer; 2005 Aug 15; 104(4):879-90. PubMed ID: 16007726
    [Abstract] [Full Text] [Related]

  • 14. Combinatorial treatments that overcome PDGFRβ-driven resistance of melanoma cells to V600EB-RAF inhibition.
    Shi H, Kong X, Ribas A, Lo RS.
    Cancer Res; 2011 Aug 01; 71(15):5067-74. PubMed ID: 21803746
    [Abstract] [Full Text] [Related]

  • 15. B-Raf(V600E) signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells.
    Cui Y, Guadagno TM.
    Oncogene; 2008 May 15; 27(22):3122-33. PubMed ID: 18071315
    [Abstract] [Full Text] [Related]

  • 16. Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells.
    Calipel A, Mouriaux F, Glotin AL, Malecaze F, Faussat AM, Mascarelli F.
    J Biol Chem; 2006 Apr 07; 281(14):9238-50. PubMed ID: 16452469
    [Abstract] [Full Text] [Related]

  • 17. Human melanoma cells expressing V600E B-RAF are susceptible to IGF1R targeting by small interfering RNAs.
    Yeh AH, Bohula EA, Macaulay VM.
    Oncogene; 2006 Oct 26; 25(50):6574-81. PubMed ID: 16715137
    [Abstract] [Full Text] [Related]

  • 18. Identification of WEE1 as a target to make AKT inhibition more effective in melanoma.
    Kuzu OF, Gowda R, Sharma A, Noory MA, Kardos G, Madhunapantula SV, Drabick JJ, Robertson GP.
    Cancer Biol Ther; 2018 Jan 02; 19(1):53-62. PubMed ID: 28853983
    [Abstract] [Full Text] [Related]

  • 19. RAF265 inhibits the growth of advanced human melanoma tumors.
    Su Y, Vilgelm AE, Kelley MC, Hawkins OE, Liu Y, Boyd KL, Kantrow S, Splittgerber RC, Short SP, Sobolik T, Zaja-Milatovic S, Dahlman KB, Amiri KI, Jiang A, Lu P, Shyr Y, Stuart DD, Levy S, Sosman JA, Richmond A.
    Clin Cancer Res; 2012 Apr 15; 18(8):2184-98. PubMed ID: 22351689
    [Abstract] [Full Text] [Related]

  • 20. Modulation of Brahma expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation.
    Mehrotra A, Saladi SV, Trivedi AR, Aras S, Qi H, Jayanthy A, Setaluri V, de la Serna IL.
    Arch Biochem Biophys; 2014 Dec 01; 563():125-35. PubMed ID: 25026375
    [Abstract] [Full Text] [Related]

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