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297 related items for PubMed ID: 23426850

  • 1. mTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death, in human nasopharyngeal carcinoma cells.
    Cai Y, Xia Q, Su Q, Luo R, Sun Y, Shi Y, Jiang W.
    Int J Mol Med; 2013 Apr; 31(4):904-12. PubMed ID: 23426850
    [Abstract] [Full Text] [Related]

  • 2. The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines.
    Ma BB, Lui VW, Hui EP, Lau CP, Ho K, Ng MH, Cheng SH, Tsao SW, Chan AT.
    Invest New Drugs; 2010 Aug; 28(4):413-20. PubMed ID: 19471857
    [Abstract] [Full Text] [Related]

  • 3. Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro.
    Liu H, Scholz C, Zang C, Schefe JH, Habbel P, Regierer AC, Schulz CO, Possinger K, Eucker J.
    Anticancer Res; 2012 May; 32(5):1627-37. PubMed ID: 22593441
    [Abstract] [Full Text] [Related]

  • 4. The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway.
    Ji D, Zhang Z, Cheng L, Chang J, Wang S, Zheng B, Zheng R, Sun Z, Wang C, Zhang Z, Liu R, Zhang X, Liu X, Wang X, Li J.
    PLoS One; 2014 May; 9(1):e85116. PubMed ID: 24416349
    [Abstract] [Full Text] [Related]

  • 5. Autophagy inhibition enhances RAD001-induced cytotoxicity in human bladder cancer cells.
    Lin JF, Lin YC, Yang SC, Tsai TF, Chen HE, Chou KY, Hwang TI.
    Drug Des Devel Ther; 2016 May; 10():1501-13. PubMed ID: 27143856
    [Abstract] [Full Text] [Related]

  • 6. Sodium butyrate induces autophagic apoptosis of nasopharyngeal carcinoma cells by inhibiting AKT/mTOR signaling.
    Huang W, Zeng C, Liu J, Yuan L, Liu W, Wang L, Zhu H, Xu Y, Luo Y, Xie D, Jiang X, Ren C.
    Biochem Biophys Res Commun; 2019 Jun 18; 514(1):64-70. PubMed ID: 31023529
    [Abstract] [Full Text] [Related]

  • 7. Abrogation of Autophagy by Chloroquine Alone or in Combination with mTOR Inhibitors Induces Apoptosis in Neuroendocrine Tumor Cells.
    Avniel-Polak S, Leibowitz G, Riahi Y, Glaser B, Gross DJ, Grozinsky-Glasberg S.
    Neuroendocrinology; 2016 Jun 18; 103(6):724-37. PubMed ID: 26619207
    [Abstract] [Full Text] [Related]

  • 8. Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 in hepatocellular carcinoma.
    Kirstein MM, Boukouris AE, Pothiraju D, Buitrago-Molina LE, Marhenke S, Schütt J, Orlik J, Kühnel F, Hegermann J, Manns MP, Vogel A.
    Liver Int; 2013 May 18; 33(5):780-93. PubMed ID: 23489999
    [Abstract] [Full Text] [Related]

  • 9. Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma.
    Ewald F, Grabinski N, Grottke A, Windhorst S, Nörz D, Carstensen L, Staufer K, Hofmann BT, Diehl F, David K, Schumacher U, Nashan B, Jücker M.
    Int J Cancer; 2013 Nov 18; 133(9):2065-76. PubMed ID: 23588885
    [Abstract] [Full Text] [Related]

  • 10. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 18; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 11. The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro.
    Liu H, Zang C, Schefe JH, Schwarzlose-Schwarck S, Regierer AC, Elstner E, Schulz CO, Scholz C, Possinger K, Eucker J.
    Anticancer Res; 2011 Sep 18; 31(9):2713-22. PubMed ID: 21868512
    [Abstract] [Full Text] [Related]

  • 12. Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells.
    Treeck O, Wackwitz B, Haus U, Ortmann O.
    Gynecol Oncol; 2006 Aug 18; 102(2):292-9. PubMed ID: 16443261
    [Abstract] [Full Text] [Related]

  • 13. Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells.
    Chiong E, Lee IL, Dadbin A, Sabichi AL, Harris L, Urbauer D, McConkey DJ, Dickstein RJ, Cheng T, Grossman HB.
    Clin Cancer Res; 2011 May 01; 17(9):2863-73. PubMed ID: 21415218
    [Abstract] [Full Text] [Related]

  • 14. Attenuation of everolimus-induced cytotoxicity by a protective autophagic pathway involving ERK activation in renal cell carcinoma cells.
    Zeng Y, Tian X, Wang Q, He W, Fan J, Gou X.
    Drug Des Devel Ther; 2018 May 01; 12():911-920. PubMed ID: 29719377
    [Abstract] [Full Text] [Related]

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  • 16. In vivo and in vitro effects of RAD001 on bladder cancer.
    Vasconcelos-Nóbrega C, Pinto-Leite R, Arantes-Rodrigues R, Ferreira R, Brochado P, Cardoso ML, Palmeira C, Salvador A, Guedes-Teixeira CI, Colaço A, Palomino LF, Lopes C, Santos L, Oliveira PA.
    Urol Oncol; 2013 Oct 01; 31(7):1212-21. PubMed ID: 22169072
    [Abstract] [Full Text] [Related]

  • 17. The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line.
    Josset E, Burckel H, Noël G, Bischoff P.
    Anticancer Res; 2013 May 01; 33(5):1845-51. PubMed ID: 23645729
    [Abstract] [Full Text] [Related]

  • 18. Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001.
    Loehberg CR, Strissel PL, Dittrich R, Strick R, Dittmer J, Dittmer A, Fabry B, Kalender WA, Koch T, Wachter DL, Groh N, Polier A, Brandt I, Lotz L, Hoffmann I, Koppitz F, Oeser S, Mueller A, Fasching PA, Lux MP, Beckmann MW, Schrauder MG.
    Biochem Pharmacol; 2012 Feb 15; 83(4):480-8. PubMed ID: 22142888
    [Abstract] [Full Text] [Related]

  • 19. Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma.
    Rosich L, Xargay-Torrent S, López-Guerra M, Campo E, Colomer D, Roué G.
    Clin Cancer Res; 2012 Oct 01; 18(19):5278-89. PubMed ID: 22879389
    [Abstract] [Full Text] [Related]

  • 20. Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression.
    Djukom C, Porro LJ, Mrazek A, Townsend CM, Hellmich MR, Chao C.
    Pancreas; 2014 Jan 01; 43(1):88-92. PubMed ID: 24263107
    [Abstract] [Full Text] [Related]

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