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Journal Abstract Search

373 related items for PubMed ID: 23427297

  • 21. Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis.
    Zhang L, Wang H, Li W, Zhong J, Yu R, Huang X, Wang H, Tan Z, Wang J, Zhang Y.
    Oncotarget; 2017 Jan 10; 8(2):3289-3303. PubMed ID: 27924057
    [Abstract] [Full Text] [Related]

  • 22. Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis.
    Zeng KW, Li N, Dong X, Ma ZZ, Jiang Y, Jin HW, Tu PF.
    Eur J Pharmacol; 2013 Aug 15; 714(1-3):261-73. PubMed ID: 23684542
    [Abstract] [Full Text] [Related]

  • 23. Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways.
    Jiang JH, Pi J, Jin H, Cai JY.
    J Cell Biochem; 2019 Mar 15; 120(3):3736-3746. PubMed ID: 30229997
    [Abstract] [Full Text] [Related]

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  • 25. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Mar 15; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 26. Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway.
    Zhu Y, Zhong Y, Long X, Zhu Z, Zhou Y, Ye H, Zeng X, Zheng X.
    Pharm Biol; 2019 Dec 15; 57(1):412-423. PubMed ID: 31230505
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  • 28. The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1α expression.
    Park MS, Kim BR, Dong SM, Lee SH, Kim DY, Rho SB.
    Oncotarget; 2014 Jul 15; 5(13):4935-44. PubMed ID: 24952732
    [Abstract] [Full Text] [Related]

  • 29. α-santalol inhibits the angiogenesis and growth of human prostate tumor growth by targeting vascular endothelial growth factor receptor 2-mediated AKT/mTOR/P70S6K signaling pathway.
    Saraswati S, Kumar S, Alhaider AA.
    Mol Cancer; 2013 Nov 22; 12():147. PubMed ID: 24261856
    [Abstract] [Full Text] [Related]

  • 30. Ginsenoside Rd regulates the Akt/mTOR/p70S6K signaling cascade and suppresses angiogenesis and breast tumor growth.
    Zhang E, Shi H, Yang L, Wu X, Wang Z.
    Oncol Rep; 2017 Jul 22; 38(1):359-367. PubMed ID: 28534996
    [Abstract] [Full Text] [Related]

  • 31. Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.
    Qazi AK, Hussain A, Khan S, Aga MA, Behl A, Ali S, Singh SK, Taneja SC, Shah BA, Saxena AK, Mondhe DM, Hamid A.
    Cancer Lett; 2015 Apr 01; 359(1):47-56. PubMed ID: 25554016
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  • 33. Piperlongumine, a piper alkaloid targets Ras/PI3K/Akt/mTOR signaling axis to inhibit tumor cell growth and proliferation in DMH/DSS induced experimental colon cancer.
    Kumar S, Agnihotri N.
    Biomed Pharmacother; 2019 Jan 01; 109():1462-1477. PubMed ID: 30551398
    [Abstract] [Full Text] [Related]

  • 34. Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
    Martinelli E, Troiani T, D'Aiuto E, Morgillo F, Vitagliano D, Capasso A, Costantino S, Ciuffreda LP, Merolla F, Vecchione L, De Vriendt V, Tejpar S, Nappi A, Sforza V, Martini G, Berrino L, De Palma R, Ciardiello F.
    Int J Cancer; 2013 Nov 01; 133(9):2089-101. PubMed ID: 23629727
    [Abstract] [Full Text] [Related]

  • 35.
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  • 36. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 01; 9():575-601. PubMed ID: 25632225
    [Abstract] [Full Text] [Related]

  • 37. SKLB-M8 induces apoptosis through the AKT/mTOR signaling pathway in melanoma models and inhibits angiogenesis with decrease of ERK1/2 phosphorylation.
    Wang J, Yang Z, Wen J, Ma F, Wang F, Yu K, Tang M, Wu W, Dong Y, Cheng X, Nie C, Chen L.
    J Pharmacol Sci; 2014 Nov 01; 126(3):198-207. PubMed ID: 25341684
    [Abstract] [Full Text] [Related]

  • 38. Polyphyllin I Promoted Melanoma Cells Autophagy and Apoptosis via PI3K/Akt/mTOR Signaling Pathway.
    Long J, Pi X.
    Biomed Res Int; 2020 Nov 01; 2020():5149417. PubMed ID: 32733943
    [Abstract] [Full Text] [Related]

  • 39. Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.
    Hou G, Zhao Q, Zhang M, Fan T, Liu M, Shi X, Ren Y, Wang Y, Zhou J, Lu Z.
    Biomed Pharmacother; 2018 Oct 01; 106():1348-1356. PubMed ID: 30119206
    [Abstract] [Full Text] [Related]

  • 40. Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer.
    Chen X, Zhao M, Hao M, Sun X, Wang J, Mao Y, Zu L, Liu J, Shen Y, Wang J, Shen K.
    Mol Cancer Res; 2013 Oct 01; 11(10):1269-78. PubMed ID: 23814023
    [Abstract] [Full Text] [Related]

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