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197 related items for PubMed ID: 23443316

  • 1. Suppression of AKT phosphorylation restores rapamycin-based synthetic lethality in SMAD4-defective pancreatic cancer cells.
    Le Gendre O, Sookdeo A, Duliepre SA, Utter M, Frias M, Foster DA.
    Mol Cancer Res; 2013 May; 11(5):474-81. PubMed ID: 23443316
    [Abstract] [Full Text] [Related]

  • 2. Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle.
    Saqcena M, Patel D, Menon D, Mukhopadhyay S, Foster DA.
    Cell Cycle; 2015 May; 14(14):2285-92. PubMed ID: 25945415
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  • 3. Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest.
    Yellen P, Chatterjee A, Preda A, Foster DA.
    Cancer Lett; 2013 Jun 10; 333(2):239-43. PubMed ID: 23376634
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  • 4. Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-β/ Smad4 axis driving the cells towards lethal EMT.
    Mohd Faheem M, Rasool RU, Ahmad SM, Jamwal VL, Chakraborty S, Katoch A, Gandhi SG, Bhagat M, Goswami A.
    Eur J Cell Biol; 2020 May 10; 99(4):151076. PubMed ID: 32439219
    [Abstract] [Full Text] [Related]

  • 5. Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells.
    Soares HP, Ni Y, Kisfalvi K, Sinnett-Smith J, Rozengurt E.
    PLoS One; 2013 May 10; 8(2):e57289. PubMed ID: 23437362
    [Abstract] [Full Text] [Related]

  • 6. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2.
    Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E.
    Mol Cancer Ther; 2015 Apr 10; 14(4):1014-23. PubMed ID: 25673820
    [Abstract] [Full Text] [Related]

  • 7. High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.
    Yellen P, Saqcena M, Salloum D, Feng J, Preda A, Xu L, Rodrik-Outmezguine V, Foster DA.
    Cell Cycle; 2011 Nov 15; 10(22):3948-56. PubMed ID: 22071574
    [Abstract] [Full Text] [Related]

  • 8. Defective TGF-beta signaling sensitizes human cancer cells to rapamycin.
    Gadir N, Jackson DN, Lee E, Foster DA.
    Oncogene; 2008 Feb 14; 27(8):1055-62. PubMed ID: 17700525
    [Abstract] [Full Text] [Related]

  • 9. mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms.
    Wilson-Edell KA, Yevtushenko MA, Rothschild DE, Rogers AN, Benz CC.
    Breast Cancer Res Treat; 2014 Apr 14; 144(2):287-298. PubMed ID: 24562770
    [Abstract] [Full Text] [Related]

  • 10. Glucagon-like peptide-1 analog-mediated protection against cholesterol-induced apoptosis via mammalian target of rapamycin activation in pancreatic βTC-6 cells -1mTORβTC-6.
    Zhou J, Wu J, Zheng F, Jin M, Li H.
    J Diabetes; 2015 Mar 14; 7(2):231-9. PubMed ID: 24909811
    [Abstract] [Full Text] [Related]

  • 11. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
    Jiang S, Zou Z, Nie P, Wen R, Xiao Y, Tang J.
    PLoS One; 2015 Mar 14; 10(7):e0132880. PubMed ID: 26176608
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  • 15. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q, Qin S, Zhang H, Liu B, Qin J, Wang X, Zhang R, Liu C, Dong X, Zhang S, Huang S, Chen L.
    J Cell Physiol; 2018 Jan 14; 233(1):516-529. PubMed ID: 28300280
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  • 16. Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2.
    Gupta M, Ansell SM, Novak AJ, Kumar S, Kaufmann SH, Witzig TE.
    Blood; 2009 Oct 01; 114(14):2926-35. PubMed ID: 19641186
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  • 17. Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling.
    Fullerton PT, Creighton CJ, Matzuk MM.
    Mol Endocrinol; 2015 Oct 01; 29(10):1440-53. PubMed ID: 26284758
    [Abstract] [Full Text] [Related]

  • 18. Rapamycin can restore the negative regulatory function of transforming growth factor beta 1 in high grade lymphomas.
    Sebestyén A, Márk Á, Hajdu M, Nagy N, Molnár A, Végső G, Barna G, Kopper L.
    Cytokine; 2015 Jun 01; 73(2):219-24. PubMed ID: 25794661
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  • 19. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T, Nishioka C, Bandobashi K, Yang Y, Kuwayama Y, Adachi Y, Takeuchi T, Koeffler HP, Taguchi H.
    Leuk Res; 2007 May 01; 31(5):673-82. PubMed ID: 17007924
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