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Journal Abstract Search

186 related items for PubMed ID: 2344359

  • 1. Mechanism-based inactivation of monoamine oxidases A and B by tetrahydropyridines and dihydropyridines.
    Krueger MJ, McKeown K, Ramsay RR, Youngster SK, Singer TP.
    Biochem J; 1990 May 15; 268(1):219-24. PubMed ID: 2344359
    [Abstract] [Full Text] [Related]

  • 2. Inactivation of monoamine oxidase by 3,3-dimethyl analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenyl-2,3-dihydropyridinium ion. Dramatic effect of beta-mercaptoethanol on substrate turnover and enzyme inactivation.
    Hiebert CK, Sayre LM, Silverman RB.
    J Biol Chem; 1989 Dec 25; 264(36):21516-21. PubMed ID: 2600079
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  • 5. Interactions of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidases.
    Singer TP, Salach JI, Castagnoli N, Trevor A.
    Biochem J; 1986 May 01; 235(3):785-9. PubMed ID: 3489461
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  • 6. Oxidation of analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidases A and B and the inhibition of monoamine oxidases by the oxidation products.
    Youngster SK, McKeown KA, Jin YZ, Ramsay RR, Heikkila RE, Singer TP.
    J Neurochem; 1989 Dec 01; 53(6):1837-42. PubMed ID: 2809594
    [Abstract] [Full Text] [Related]

  • 7. Interactions of the neurotoxin MPTP and its demethylated derivative (PTP) with monoamine oxidase-B.
    Sullivan JP, Tipton KF.
    Neurochem Res; 1992 Aug 01; 17(8):791-6. PubMed ID: 1641061
    [Abstract] [Full Text] [Related]

  • 8. Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).
    Herraiz T, Arán VJ, Guillén H.
    Free Radic Res; 2009 Oct 01; 43(10):975-84. PubMed ID: 19669997
    [Abstract] [Full Text] [Related]

  • 9. Mechanistic studies on the monoamine oxidase B catalyzed oxidation of 1,4-disubstituted tetrahydropyridines.
    Kuttab S, Kalgutkar A, Castagnoli N.
    Chem Res Toxicol; 1994 Oct 01; 7(6):740-4. PubMed ID: 7696527
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of novel MPTP analogs as potential monoamine oxidase B (MAO-B) inhibitors.
    Kalgutkar AS, Castagnoli N.
    J Med Chem; 1992 Oct 30; 35(22):4165-74. PubMed ID: 1433219
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  • 11. Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
    Pretorius A, Ogunrombi MO, Terre'blanche G, Castagnoli N, Bergh JJ, Petzer JP.
    Bioorg Med Chem; 2008 Oct 01; 16(19):8813-7. PubMed ID: 18799315
    [Abstract] [Full Text] [Related]

  • 12. Analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as monoamine oxidase substrates: a second ring is not necessary.
    Gibb C, Willoughby J, Glover V, Sandler M, Testa B, Jenner P, Marsden CD.
    Neurosci Lett; 1987 May 19; 76(3):316-22. PubMed ID: 3495757
    [Abstract] [Full Text] [Related]

  • 13. Oxidation of 1-amino-4-phenyl-1,2,3,6-tetrahydropyridine, a 1-amino analog of MPTP, by type A and B monoamine oxidase.
    Umeda M, Aoyama S, Kaiya T, Kohda K, Maruyama W, Naoi M.
    J Neural Transm (Vienna); 1998 May 19; 105(10-12):1253-64. PubMed ID: 9928894
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  • 14. Probing the mechanism of bioactivation of MPTP type analogs by monoamine oxidase B: structure-activity studies on substituted 4-phenoxy-, 4-phenyl-, and 4-thiophenoxy-1-cyclopropyl-1,2,3,6-tetrahydropyridines.
    Rimoldi JM, Wang YX, Nimkar SK, Kuttab SH, Anderson AH, Burch H, Castagnoli N.
    Chem Res Toxicol; 1995 May 19; 8(5):703-10. PubMed ID: 7548753
    [Abstract] [Full Text] [Related]

  • 15. Metabolic studies on the nigrostriatal toxin MPTP and its MAO B generated dihydropyridinium metabolite MPDP+.
    Wu E, Shinka T, Caldera-Munoz P, Yoshizumi H, Trevor A, Castagnoli N.
    Chem Res Toxicol; 1988 May 19; 1(3):186-94. PubMed ID: 2979730
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  • 16. Studies on the 1-methyl-4-phenyl-2,3-dihydropyridinium species 2,3-MPDP+, the monoamine oxidase catalyzed oxidation product of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Peterson LA, Caldera PS, Trevor A, Chiba K, Castagnoli N.
    J Med Chem; 1985 Oct 19; 28(10):1432-6. PubMed ID: 3876442
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and monoamine oxidase B substrate properties of 1-methyl-4-heteroaryl-1,2,3,6-tetrahydropyridines.
    Yu J, Castagnoli N.
    Bioorg Med Chem; 1999 Dec 19; 7(12):2835-42. PubMed ID: 10658587
    [Abstract] [Full Text] [Related]

  • 18. Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP.
    Salach JI, Singer TP, Castagnoli N, Trevor A.
    Biochem Biophys Res Commun; 1984 Dec 14; 125(2):831-5. PubMed ID: 6335034
    [Abstract] [Full Text] [Related]

  • 19. Oxidation products arising from the action of monoamine oxidase B on 1-methyl-4-benzyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Sablin SO, Krueger MJ, Bachurin SO, Solyakov LS, Efange SM, Singer TP.
    J Neurochem; 1994 May 14; 62(5):2012-6. PubMed ID: 8158148
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to toxic pyridinium cations by monoamine oxidase (MAO) enzymes and its use to search for new MAO inhibitors and protective agents.
    Herraiz T.
    J Enzyme Inhib Med Chem; 2012 Dec 14; 27(6):810-7. PubMed ID: 21992679
    [Abstract] [Full Text] [Related]

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