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238 related items for PubMed ID: 2344370
21. The role of NAD(P)H: quinone reductase (EC 1.6.99.2, DT-diaphorase) in the reductive bioactivation of the novel indoloquinone antitumor agent EO9. Walton MI, Smith PJ, Workman P. Cancer Commun; 1991 Jul; 3(7):199-206. PubMed ID: 1714284 [Abstract] [Full Text] [Related]
22. Reductive metabolism of the nitroimidazole-based hypoxia-selective cytotoxin NLCQ-1 (NSC 709257). Papadopoulou MV, Ji M, Rao MK, Bloomer WD. Oncol Res; 2003 Jul; 14(1):21-9. PubMed ID: 14552588 [Abstract] [Full Text] [Related]
23. Adaptation of human tumor cells to tirapazamine under aerobic conditions: implications of increased antioxidant enzyme activity to mechanism of aerobic cytotoxicity. Elwell JH, Siim BG, Evans JW, Brown JM. Biochem Pharmacol; 1997 Jul 15; 54(2):249-57. PubMed ID: 9271329 [Abstract] [Full Text] [Related]
24. Enzymology of the reduction of the novel fused pyrazine mono-n-oxide bioreductive drug, RB90740 roles for P450 reductase and cytochrome b5 reductase. Barham HM, Stratford IJ. Biochem Pharmacol; 1996 Mar 22; 51(6):829-37. PubMed ID: 8602879 [Abstract] [Full Text] [Related]
25. Genotoxic effects of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and nitrogen mustard-N-oxide (nitromin) in Walker carcinoma cells under aerobic and hypoxic conditions. Cahill A, Jenkins TC, Pickering P, White IN. Chem Biol Interact; 1995 Mar 30; 95(1-2):97-107. PubMed ID: 7697757 [Abstract] [Full Text] [Related]
26. Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy. Stiborová M, Frei E, Sopko B, Wiessler M, Schmeiser HH. Carcinogenesis; 2002 Apr 30; 23(4):617-25. PubMed ID: 11960915 [Abstract] [Full Text] [Related]
27. Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR 4233). Patterson AV, Barham HM, Chinje EC, Adams GE, Harris AL, Stratford IJ. Br J Cancer; 1995 Nov 30; 72(5):1144-50. PubMed ID: 7577460 [Abstract] [Full Text] [Related]
28. Acute lesions in rats caused by 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) or nitromin: a comparison with rates of reduction in microsomal systems from target organs. White IN, Cahill A, Davies A, Carthew P. Arch Toxicol; 1992 Nov 30; 66(2):100-6. PubMed ID: 1605723 [Abstract] [Full Text] [Related]
30. Epoxide reductase activity of mammalian liver cytosols and aldehyde oxidase. Hirao Y, Kitamura S, Tatsumi K. Carcinogenesis; 1994 Apr 30; 15(4):739-43. PubMed ID: 8149489 [Abstract] [Full Text] [Related]
31. Neonicotinoid insecticides: reduction and cleavage of imidacloprid nitroimine substituent by liver microsomal and cytosolic enzymes. Schulz-Jander DA, Leimkuehler WM, Casida JE. Chem Res Toxicol; 2002 Sep 30; 15(9):1158-65. PubMed ID: 12230409 [Abstract] [Full Text] [Related]
32. NAD(P)H: quinone oxidoreductase (DT-diaphorase) in chick embryo liver. Comparison to activity in rat and guinea pig liver and differences in co-induction with 7-ethoxyresorufin deethylase by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Spencer CB, Rifkind AB. Biochem Pharmacol; 1990 Jan 15; 39(2):327-35. PubMed ID: 2105732 [Abstract] [Full Text] [Related]
33. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1. Keyes SR, Fracasso PM, Heimbrook DC, Rockwell S, Sligar SG, Sartorelli AC. Cancer Res; 1984 Dec 15; 44(12 Pt 1):5638-43. PubMed ID: 6437671 [Abstract] [Full Text] [Related]
34. Bioreductive metabolism of SR-4233 (WIN 59075) by whole cell suspensions under aerobic and hypoxic conditions: role of the pentose cycle and implications for the mechanism of cytotoxicity observed in air. Tuttle SW, Hazard L, Koch CJ, Mitchell JB, Coleman CN, Biaglow JE. Int J Radiat Oncol Biol Phys; 1994 May 15; 29(2):357-62. PubMed ID: 8195033 [Abstract] [Full Text] [Related]
35. Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved? Aiyar J, De Flora S, Wetterhahn KE. Carcinogenesis; 1992 Jul 15; 13(7):1159-66. PubMed ID: 1379126 [Abstract] [Full Text] [Related]
36. Aerobic 2- and 4-nitroreduction of CB 1954 by human liver. Tang MH, Helsby NA, Wilson WR, Tingle MD. Toxicology; 2005 Dec 15; 216(2-3):129-39. PubMed ID: 16129536 [Abstract] [Full Text] [Related]
38. Lack of competition between cytochrome c and anthraquinone type drugs for the reductive sites of NADH dehydrogenase. Tarasiuk J, Garnier-Suillerot A, Borowski E. Biochem Pharmacol; 1989 Jul 15; 38(14):2285-9. PubMed ID: 2546562 [Abstract] [Full Text] [Related]
39. Reductive metabolism of the sanguinarine iminium bond by rat liver preparations. Wu Y, Liu ZY, Cao Y, Chen XJ, Zeng JG, Sun ZL. Pharmacol Rep; 2013 Jul 15; 65(5):1391-400. PubMed ID: 24399736 [Abstract] [Full Text] [Related]
40. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells. Siegel D, Gibson NW, Preusch PC, Ross D. Cancer Res; 1990 Nov 15; 50(22):7293-300. PubMed ID: 2121335 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]