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232 related items for PubMed ID: 23470529

  • 1. Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca2+/calmodulin signaling.
    Kaminskyy VO, Surova OV, Piskunova T, Zborovskaya IB, Tchevkina EM, Andera L, Zhivotovsky B.
    Cell Death Dis; 2013 Mar 07; 4(3):e522. PubMed ID: 23470529
    [Abstract] [Full Text] [Related]

  • 2. Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.
    Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG, Longley DB.
    Cell Death Differ; 2009 Oct 07; 16(10):1352-61. PubMed ID: 19543235
    [Abstract] [Full Text] [Related]

  • 3. Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.
    Van Geelen CM, Pennarun B, Ek WB, Le PT, Spierings DC, De Vries EG, De Jong S.
    Int J Oncol; 2010 Oct 07; 37(4):1031-41. PubMed ID: 20811726
    [Abstract] [Full Text] [Related]

  • 4. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X, Yue P, Chen S, Hu L, Lonial S, Khuri FR, Sun SY.
    Cancer Res; 2007 May 15; 67(10):4981-8. PubMed ID: 17510429
    [Abstract] [Full Text] [Related]

  • 5. Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions.
    Zhuang H, Jiang W, Zhang X, Qiu F, Gan Z, Cheng W, Zhang J, Guan S, Tang B, Huang Q, Wu X, Huang X, Jiang W, Hu Q, Lu M, Hua ZC.
    J Mol Med (Berl); 2013 Feb 15; 91(2):219-35. PubMed ID: 22948392
    [Abstract] [Full Text] [Related]

  • 6. Calmodulin inhibition contributes to sensitize TRAIL-induced apoptosis in human lung cancer H1299 cells.
    Hwang MK, Min YK, Kim SH.
    Biochem Cell Biol; 2009 Dec 15; 87(6):919-26. PubMed ID: 19935877
    [Abstract] [Full Text] [Related]

  • 7. Dissecting the roles of DR4, DR5 and c-FLIP in the regulation of geranylgeranyltransferase I inhibition-mediated augmentation of TRAIL-induced apoptosis.
    Chen S, Fu L, Raja SM, Yue P, Khuri FR, Sun SY.
    Mol Cancer; 2010 Jan 29; 9():23. PubMed ID: 20113484
    [Abstract] [Full Text] [Related]

  • 8. Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells.
    Zhu ZC, Liu JW, Yang C, Li MJ, Wu RJ, Xiong ZQ.
    Cell Death Dis; 2019 Feb 11; 10(2):118. PubMed ID: 30742128
    [Abstract] [Full Text] [Related]

  • 9. Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers.
    Nam SY, Jung GA, Hur GC, Chung HY, Kim WH, Seol DW, Lee BL.
    Cancer Sci; 2003 Dec 11; 94(12):1066-73. PubMed ID: 14662022
    [Abstract] [Full Text] [Related]

  • 10. High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde.
    Kim HB, Kim MJ, Kim DY, Lee JW, Bae JH, Kim DW, Kang CD, Kim SH.
    Mol Cancer; 2011 Apr 25; 10():46. PubMed ID: 21513580
    [Abstract] [Full Text] [Related]

  • 11. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.
    Mol Cancer Ther; 2007 Jul 25; 6(7):2029-38. PubMed ID: 17604333
    [Abstract] [Full Text] [Related]

  • 12. Protective effect of RIP and c-FLIP in preventing liver cancer cell apoptosis induced by TRAIL.
    Sun J, Luo H, Nie W, Xu X, Miao X, Huang F, Wu H, Jin X.
    Int J Clin Exp Pathol; 2015 Jul 25; 8(6):6519-25. PubMed ID: 26261530
    [Abstract] [Full Text] [Related]

  • 13. Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL.
    Gómez-Benito M, Martinez-Lorenzo MJ, Anel A, Marzo I, Naval J.
    Exp Cell Res; 2007 Jul 01; 313(11):2378-88. PubMed ID: 17462628
    [Abstract] [Full Text] [Related]

  • 14. Human embryonic and induced pluripotent stem cells express TRAIL receptors and can be sensitized to TRAIL-induced apoptosis.
    Vinarsky V, Krivanek J, Rankel L, Nahacka Z, Barta T, Jaros J, Andera L, Hampl A.
    Stem Cells Dev; 2013 Nov 15; 22(22):2964-74. PubMed ID: 23806100
    [Abstract] [Full Text] [Related]

  • 15. Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals.
    Seal S, Hockenbery DM, Spaulding EY, Kiem HP, Abbassi N, Deeg HJ.
    Exp Hematol; 2008 Dec 15; 36(12):1660-72. PubMed ID: 18838202
    [Abstract] [Full Text] [Related]

  • 16. Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation.
    Kim JY, Kim EH, Park SS, Lim JH, Kwon TK, Choi KS.
    J Cell Biochem; 2008 Dec 15; 105(6):1386-98. PubMed ID: 18980244
    [Abstract] [Full Text] [Related]

  • 17. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells.
    Wang X, Chen W, Zeng W, Bai L, Tesfaigzi Y, Belinsky SA, Lin Y.
    Mol Cancer Ther; 2008 May 15; 7(5):1156-63. PubMed ID: 18483303
    [Abstract] [Full Text] [Related]

  • 18. Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2.
    Lee SJ, Kim EA, Song KS, Kim MJ, Lee DH, Kwon TK, Lee TJ.
    Int J Oncol; 2012 Oct 15; 41(4):1425-30. PubMed ID: 22842544
    [Abstract] [Full Text] [Related]

  • 19. Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8.
    Chacko AD, Liberante F, Paul I, Longley DB, Fennell DA.
    BMC Cancer; 2010 Jul 20; 10():380. PubMed ID: 20646307
    [Abstract] [Full Text] [Related]

  • 20. Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
    Song JH, Bellail A, Tse MC, Yong VW, Hao C.
    J Neurosci; 2006 Mar 22; 26(12):3299-308. PubMed ID: 16554480
    [Abstract] [Full Text] [Related]

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