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Journal Abstract Search
171 related items for PubMed ID: 23480856
21. Design and synthesis of bicyclic acetals as Beta Secretase (BACE1) inhibitors. Innocenti R, Lenci E, Menchi G, Pupi A, Trabocchi A. Bioorg Med Chem; 2017 Oct 01; 25(19):5077-5083. PubMed ID: 28359674 [Abstract] [Full Text] [Related]
22. The selective BACE1 inhibitor VIa reduces amyloid-β production in cell and mouse models of Alzheimer's disease. Cheng X, Zhou Y, Gu W, Wu J, Nie A, Cheng J, Zhou J, Zhou W, Zhang Y. J Alzheimers Dis; 2013 Oct 01; 37(4):823-34. PubMed ID: 23948917 [Abstract] [Full Text] [Related]
29. Dynamic Simulation, Docking and DFT Studies Applied to a Set of Anti-Acetylcholinesterase Inhibitors in the enzyme β-Secretase (BACE-1): An Important Therapeutic Target in Alzheimer`s disease. Silva-Junior EF, Barcellos Franca PH, Quintans-Junior LJ, Mendonca-Junior FJB, Scotti L, Scotti MT, de Aquino TM, de Araujo-Junior JX. Curr Comput Aided Drug Des; 2017 Nov 10; 13(4):266-274. PubMed ID: 28382866 [Abstract] [Full Text] [Related]
30. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis. Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W. Eur J Neurosci; 2013 Jun 10; 37(12):1962-9. PubMed ID: 23773065 [Abstract] [Full Text] [Related]
31. Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors. Volgraf M, Chan L, Huestis MP, Purkey HE, Burkard M, Geck Do M, Harris J, Hunt KW, Liu X, Lyssikatos JP, Rana S, Thomas AA, Vigers GP, Siu M. Bioorg Med Chem Lett; 2014 Jun 01; 24(11):2477-80. PubMed ID: 24780121 [Abstract] [Full Text] [Related]
32. Interaction mechanism exploration of HEA derivatives as BACE1 inhibitors by in silico analysis. Wu Q, Li X, Gao Q, Wang J, Li Y, Yang L. Mol Biosyst; 2016 Apr 01; 12(4):1151-65. PubMed ID: 26915506 [Abstract] [Full Text] [Related]