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281 related items for PubMed ID: 23486205
1. Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability. Fritz E, Izaurieta P, Weiss A, Mir FR, Rojas P, Gonzalez D, Rojas F, Brown RH, Madrid R, van Zundert B. J Neurophysiol; 2013 Jun; 109(11):2803-14. PubMed ID: 23486205 [Abstract] [Full Text] [Related]
2. Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress. Rojas F, Cortes N, Abarzua S, Dyrda A, van Zundert B. Front Cell Neurosci; 2014 Jun; 8():24. PubMed ID: 24570655 [Abstract] [Full Text] [Related]
3. Chronic infusion of SOD1G93A astrocyte-secreted factors induces spinal motoneuron degeneration and neuromuscular dysfunction in healthy rats. Ramírez-Jarquín UN, Rojas F, van Zundert B, Tapia R. J Cell Physiol; 2017 Oct; 232(10):2610-2615. PubMed ID: 28128448 [Abstract] [Full Text] [Related]
4. Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Rojas F, Gonzalez D, Cortes N, Ampuero E, Hernández DE, Fritz E, Abarzua S, Martinez A, Elorza AA, Alvarez A, Court F, van Zundert B. Front Cell Neurosci; 2015 Oct; 9():203. PubMed ID: 26106294 [Abstract] [Full Text] [Related]
5. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1. Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC. Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261 [Abstract] [Full Text] [Related]
6. Expression of mutant SOD1 in astrocytes induces functional deficits in motoneuron mitochondria. Bilsland LG, Nirmalananthan N, Yip J, Greensmith L, Duchen MR. J Neurochem; 2008 Dec; 107(5):1271-83. PubMed ID: 18808448 [Abstract] [Full Text] [Related]
7. Voltage-gated calcium channels are abnormal in cultured spinal motoneurons in the G93A-SOD1 transgenic mouse model of ALS. Chang Q, Martin LJ. Neurobiol Dis; 2016 Sep; 93():78-95. PubMed ID: 27151771 [Abstract] [Full Text] [Related]
8. The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes. König HG, Coughlan KS, Kinsella S, Breen BA, Prehn JH. Neurobiol Dis; 2014 Oct; 70():99-107. PubMed ID: 24956542 [Abstract] [Full Text] [Related]
9. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S. Nat Neurosci; 2007 May; 10(5):615-22. PubMed ID: 17435755 [Abstract] [Full Text] [Related]
10. IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1. Aebischer J, Cassina P, Otsmane B, Moumen A, Seilhean D, Meininger V, Barbeito L, Pettmann B, Raoul C. Cell Death Differ; 2011 May; 18(5):754-68. PubMed ID: 21072055 [Abstract] [Full Text] [Related]
12. Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. Lino MM, Schneider C, Caroni P. J Neurosci; 2002 Jun 15; 22(12):4825-32. PubMed ID: 12077179 [Abstract] [Full Text] [Related]
13. Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis. Quinlan KA, Schuster JE, Fu R, Siddique T, Heckman CJ. J Physiol; 2011 May 01; 589(Pt 9):2245-60. PubMed ID: 21486770 [Abstract] [Full Text] [Related]
14. Inhibitory synaptic regulation of motoneurons: a new target of disease mechanisms in amyotrophic lateral sclerosis. Martin LJ, Chang Q. Mol Neurobiol; 2012 Feb 01; 45(1):30-42. PubMed ID: 22072396 [Abstract] [Full Text] [Related]
15. Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons. Lautenschläger J, Prell T, Ruhmer J, Weidemann L, Witte OW, Grosskreutz J. Exp Neurol; 2013 Sep 01; 247():91-100. PubMed ID: 23578819 [Abstract] [Full Text] [Related]
16. Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice. Kuo JJ, Schonewille M, Siddique T, Schults AN, Fu R, Bär PR, Anelli R, Heckman CJ, Kroese AB. J Neurophysiol; 2004 Jan 01; 91(1):571-5. PubMed ID: 14523070 [Abstract] [Full Text] [Related]
17. Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis. Miquel E, Cassina A, Martínez-Palma L, Bolatto C, Trías E, Gandelman M, Radi R, Barbeito L, Cassina P. PLoS One; 2012 Jan 01; 7(4):e34776. PubMed ID: 22509356 [Abstract] [Full Text] [Related]
18. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis. Beqollari D, Romberg CF, Dobrowolny G, Martini M, Voss AA, Musarò A, Bannister RA. Skelet Muscle; 2016 Jan 01; 6():24. PubMed ID: 27340545 [Abstract] [Full Text] [Related]