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Journal Abstract Search

95 related items for PubMed ID: 23505041

  • 1. Design and testing of bicyclic inhibitors of Grb7--are two cycles better than one?
    Gunzburg MJ, Ambaye ND, Del Borgo MP, Perlmutter P, Wilce JA.
    Biopolymers; 2013 Sep; 100(5):543-9. PubMed ID: 23505041
    [Abstract] [Full Text] [Related]

  • 2. Interaction of the non-phosphorylated peptide G7-18NATE with Grb7-SH2 domain requires phosphate for enhanced affinity and specificity.
    Gunzburg MJ, Ambaye ND, Del Borgo MP, Pero SC, Krag DN, Wilce MC, Wilce JA.
    J Mol Recognit; 2012 Jan; 25(1):57-67. PubMed ID: 22213451
    [Abstract] [Full Text] [Related]

  • 3. Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.
    Porter CJ, Matthews JM, Mackay JP, Pursglove SE, Schmidberger JW, Leedman PJ, Pero SC, Krag DN, Wilce MC, Wilce JA.
    BMC Struct Biol; 2007 Sep 25; 7():58. PubMed ID: 17894853
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  • 4. Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity.
    Sang J, Kulkarni K, Watson GM, Ma X, Craik DJ, Henriques ST, Poth AG, Benfield AH, Wilce JA.
    Molecules; 2019 Oct 17; 24(20):. PubMed ID: 31627265
    [Abstract] [Full Text] [Related]

  • 5. Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression.
    Ambaye ND, Pero SC, Gunzburg MJ, Yap M, Clayton DJ, Del Borgo MP, Perlmutter P, Aguilar MI, Shukla GS, Peletskaya E, Cookson MM, Krag DN, Wilce MC, Wilce JA.
    J Mol Biol; 2011 Sep 23; 412(3):397-411. PubMed ID: 21802427
    [Abstract] [Full Text] [Related]

  • 6. Uptake of a cell permeable G7-18NATE contruct into cells and binding with the Grb-7-SH2 domain.
    Ambaye ND, Lim RC, Clayton DJ, Gunzburg MJ, Price JT, Pero SC, Krag DN, Wilce MC, Aguilar MI, Perlmutter P, Wilce JA.
    Biopolymers; 2011 Sep 23; 96(2):181-8. PubMed ID: 20564009
    [Abstract] [Full Text] [Related]

  • 7. Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
    Watson GM, Gunzburg MJ, Ambaye ND, Lucas WA, Traore DA, Kulkarni K, Cergol KM, Payne RJ, Panjikar S, Pero SC, Perlmutter P, Wilce MC, Wilce JA.
    J Med Chem; 2015 Oct 08; 58(19):7707-18. PubMed ID: 26359549
    [Abstract] [Full Text] [Related]

  • 8. Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
    Watson GM, Kulkarni K, Sang J, Ma X, Gunzburg MJ, Perlmutter P, Wilce MCJ, Wilce JA.
    J Med Chem; 2017 Nov 22; 60(22):9349-9359. PubMed ID: 29083893
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  • 13. Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability.
    Sturre NP, Colson RN, Shah N, Watson GM, Yang X, Wilce MCJ, Price JT, Wilce JA.
    Biomedicines; 2022 May 16; 10(5):. PubMed ID: 35625882
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  • 15. Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells.
    Pero SC, Shukla GS, Cookson MM, Flemer S, Krag DN.
    Br J Cancer; 2007 May 21; 96(10):1520-5. PubMed ID: 17426702
    [Abstract] [Full Text] [Related]

  • 16. Specific peptide ligand for Grb7 signal transduction protein and pancreatic cancer metastasis.
    Tanaka S, Pero SC, Taguchi K, Shimada M, Mori M, Krag DN, Arii S.
    J Natl Cancer Inst; 2006 Apr 05; 98(7):491-8. PubMed ID: 16595785
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  • 18. Direct Interaction between Calmodulin and the Grb7 RA-PH Domain.
    Watson GM, Wilce JA.
    Int J Mol Sci; 2020 Feb 17; 21(4):. PubMed ID: 32079204
    [Abstract] [Full Text] [Related]

  • 19. Development of binding assays for the SH2 domain of Grb7 and Grb2 using fluorescence polarization.
    Luzy JP, Chen H, Gril B, Liu WQ, Vidal M, Perdereau D, Burnol AF, Garbay C.
    J Biomol Screen; 2008 Feb 17; 13(2):112-9. PubMed ID: 18216394
    [Abstract] [Full Text] [Related]

  • 20. Calorimetric investigation of phosphorylated and non-phosphorylated peptide ligand binding to the human Grb7-SH2 domain.
    Spuches AM, Argiros HJ, Lee KH, Haas LL, Pero SC, Krag DN, Roller PP, Wilcox DE, Lyons BA.
    J Mol Recognit; 2007 Feb 17; 20(4):245-52. PubMed ID: 17705331
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