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369 related items for PubMed ID: 23507969

  • 1. FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
    Wang R, Wang Y, Liu N, Ren C, Jiang C, Zhang K, Yu S, Chen Y, Tang H, Deng Q, Fu C, Wang Y, Li R, Liu M, Pan W, Wang P.
    Cell Res; 2013 Jun; 23(6):803-19. PubMed ID: 23507969
    [Abstract] [Full Text] [Related]

  • 2. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M.
    J Biol Chem; 2015 Apr 17; 290(16):10368-81. PubMed ID: 25670854
    [Abstract] [Full Text] [Related]

  • 3. The FBW7-KLF2 axis regulates endothelial functions.
    Zhao Y, Sun Y.
    Cell Res; 2013 Jun 17; 23(6):741-3. PubMed ID: 23567558
    [Abstract] [Full Text] [Related]

  • 4. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB, Dodard-Friedman I, Blank V.
    J Biol Chem; 2015 Oct 23; 290(43):26292-302. PubMed ID: 26306035
    [Abstract] [Full Text] [Related]

  • 5. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.
    Nature; 2011 Mar 03; 471(7336):104-9. PubMed ID: 21368833
    [Abstract] [Full Text] [Related]

  • 6. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
    Liu N, Li H, Li S, Shen M, Xiao N, Chen Y, Wang Y, Wang W, Wang R, Wang Q, Sun J, Wang P.
    J Biol Chem; 2010 Jun 11; 285(24):18858-67. PubMed ID: 20388706
    [Abstract] [Full Text] [Related]

  • 7. A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).
    Bialkowska AB, Liu Y, Nandan MO, Yang VW.
    J Biol Chem; 2014 Feb 28; 289(9):5997-6005. PubMed ID: 24398687
    [Abstract] [Full Text] [Related]

  • 8. E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
    Lochab S, Pal P, Kapoor I, Kanaujiya JK, Sanyal S, Behre G, Trivedi AK.
    Biochim Biophys Acta; 2013 Dec 28; 1833(12):2639-2652. PubMed ID: 23820376
    [Abstract] [Full Text] [Related]

  • 9. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K, Hiramatsu Y, Uchida C, Isobe T, Hattori T, Oda T, Shibata K, Nakamura S, Kikuchi A, Kitagawa M.
    Oncogene; 2009 Jun 25; 28(25):2393-405. PubMed ID: 19421138
    [Abstract] [Full Text] [Related]

  • 10. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
    Zhao D, Zheng HQ, Zhou Z, Chen C.
    Cancer Res; 2010 Jun 01; 70(11):4728-38. PubMed ID: 20484041
    [Abstract] [Full Text] [Related]

  • 11. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.
    Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W.
    Cell Rep; 2012 May 31; 1(5):434-43. PubMed ID: 22708077
    [Abstract] [Full Text] [Related]

  • 12. Physiological Functions of FBW7 in Metabolism.
    Zhang J, Kong DH, Huang X, Yu R, Yang Y.
    Horm Metab Res; 2022 May 31; 54(5):280-287. PubMed ID: 35533672
    [Abstract] [Full Text] [Related]

  • 13. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE.
    Proc Natl Acad Sci U S A; 2004 Jun 15; 101(24):9085-90. PubMed ID: 15150404
    [Abstract] [Full Text] [Related]

  • 14. FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
    Suryo Rahmanto A, Savov V, Brunner A, Bolin S, Weishaupt H, Malyukova A, Rosén G, Čančer M, Hutter S, Sundström A, Kawauchi D, Jones DT, Spruck C, Taylor MD, Cho YJ, Pfister SM, Kool M, Korshunov A, Swartling FJ, Sangfelt O.
    EMBO J; 2016 Oct 17; 35(20):2192-2212. PubMed ID: 27625374
    [Abstract] [Full Text] [Related]

  • 15. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T, Hattori T, Kitagawa K, Uchida C, Kotake Y, Kosugi I, Oda T, Kitagawa M.
    J Biol Chem; 2009 Oct 09; 284(41):27766-27779. PubMed ID: 19679664
    [Abstract] [Full Text] [Related]

  • 16. The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
    Biswas M, Phan D, Watanabe M, Chan JY.
    J Biol Chem; 2011 Nov 11; 286(45):39282-9. PubMed ID: 21953459
    [Abstract] [Full Text] [Related]

  • 17. Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3β-Dependent Manner.
    Kumar Y, Shukla N, Thacker G, Kapoor I, Lochab S, Bhatt ML, Chattopadhyay N, Sanyal S, Trivedi AK.
    Mol Cancer Res; 2016 Nov 11; 14(11):1097-1109. PubMed ID: 27470268
    [Abstract] [Full Text] [Related]

  • 18. CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion.
    Jin X, Yang C, Fan P, Xiao J, Zhang W, Zhan S, Liu T, Wang D, Wu H.
    J Biol Chem; 2017 Apr 14; 292(15):6269-6280. PubMed ID: 28242758
    [Abstract] [Full Text] [Related]

  • 19. GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α.
    Flügel D, Görlach A, Kietzmann T.
    Blood; 2012 Feb 02; 119(5):1292-301. PubMed ID: 22144179
    [Abstract] [Full Text] [Related]

  • 20. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
    Xu Y, Sengupta T, Kukreja L, Minella AC.
    J Biol Chem; 2010 Nov 05; 285(45):34439-46. PubMed ID: 20826802
    [Abstract] [Full Text] [Related]

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