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Journal Abstract Search

790 related items for PubMed ID: 23508784

  • 1.
    ; . PubMed ID:
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  • 2. Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy.
    Witjas-Paalberends ER, Piroddi N, Stam K, van Dijk SJ, Oliviera VS, Ferrara C, Scellini B, Hazebroek M, ten Cate FJ, van Slegtenhorst M, dos Remedios C, Niessen HW, Tesi C, Stienen GJ, Heymans S, Michels M, Poggesi C, van der Velden J.
    Cardiovasc Res; 2013 Aug 01; 99(3):432-41. PubMed ID: 23674513
    [Abstract] [Full Text] [Related]

  • 3. Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function.
    van Dijk SJ, Paalberends ER, Najafi A, Michels M, Sadayappan S, Carrier L, Boontje NM, Kuster DW, van Slegtenhorst M, Dooijes D, dos Remedios C, ten Cate FJ, Stienen GJ, van der Velden J.
    Circ Heart Fail; 2012 Jan 01; 5(1):36-46. PubMed ID: 22178992
    [Abstract] [Full Text] [Related]

  • 4. ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.
    Sequeira V, Najafi A, Wijnker PJ, Dos Remedios CG, Michels M, Kuster DW, van der Velden J.
    Proc Natl Acad Sci U S A; 2015 Dec 15; 112(50):E7003-12. PubMed ID: 26621701
    [Abstract] [Full Text] [Related]

  • 5. Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model.
    Najafi A, Sequeira V, Helmes M, Bollen IA, Goebel M, Regan JA, Carrier L, Kuster DW, Van Der Velden J.
    Cardiovasc Res; 2016 May 15; 110(2):200-14. PubMed ID: 26825555
    [Abstract] [Full Text] [Related]

  • 6. Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations.
    Witjas-Paalberends ER, Güçlü A, Germans T, Knaapen P, Harms HJ, Vermeer AM, Christiaans I, Wilde AA, Dos Remedios C, Lammertsma AA, van Rossum AC, Stienen GJ, van Slegtenhorst M, Schinkel AF, Michels M, Ho CY, Poggesi C, van der Velden J.
    Cardiovasc Res; 2014 Jul 15; 103(2):248-57. PubMed ID: 24835277
    [Abstract] [Full Text] [Related]

  • 7. Hypertrophic cardiomyopathy mutations increase myofilament Ca2+ buffering, alter intracellular Ca2+ handling, and stimulate Ca2+-dependent signaling.
    Robinson P, Liu X, Sparrow A, Patel S, Zhang YH, Casadei B, Watkins H, Redwood C.
    J Biol Chem; 2018 Jul 06; 293(27):10487-10499. PubMed ID: 29760186
    [Abstract] [Full Text] [Related]

  • 8. Somatic MYH7, MYBPC3, TPM1, TNNT2 and TNNI3 mutations in sporadic hypertrophic cardiomyopathy.
    Núñez L, Gimeno-Blanes JR, Rodríguez-García MI, Monserrat L, Zorio E, Coats C, McGregor CG, Hernandez del Rincón JP, Castro-Beiras A, Hermida-Prieto M.
    Circ J; 2013 Jul 06; 77(9):2358-65. PubMed ID: 23782526
    [Abstract] [Full Text] [Related]

  • 9. Lifelong Clinical Impact of the Presence of Sarcomere Gene Mutation in Japanese Patients With Hypertrophic Cardiomyopathy.
    Nakashima Y, Kubo T, Sugiura K, Ochi Y, Takahashi A, Baba Y, Hirota T, Yamasaki N, Kimura A, Doi YL, Kitaoka H.
    Circ J; 2020 Sep 25; 84(10):1846-1853. PubMed ID: 32830170
    [Abstract] [Full Text] [Related]

  • 10. Diagnostic yield, interpretation, and clinical utility of mutation screening of sarcomere encoding genes in Danish hypertrophic cardiomyopathy patients and relatives.
    Andersen PS, Havndrup O, Hougs L, Sørensen KM, Jensen M, Larsen LA, Hedley P, Thomsen AR, Moolman-Smook J, Christiansen M, Bundgaard H.
    Hum Mutat; 2009 Mar 25; 30(3):363-70. PubMed ID: 19035361
    [Abstract] [Full Text] [Related]

  • 11. Mavacamten rescues increased myofilament calcium sensitivity and dysregulation of Ca2+ flux caused by thin filament hypertrophic cardiomyopathy mutations.
    Sparrow AJ, Watkins H, Daniels MJ, Redwood C, Robinson P.
    Am J Physiol Heart Circ Physiol; 2020 Mar 01; 318(3):H715-H722. PubMed ID: 32083971
    [Abstract] [Full Text] [Related]

  • 12. Clinical outcomes associated with sarcomere mutations in hypertrophic cardiomyopathy: a meta-analysis on 7675 individuals.
    Sedaghat-Hamedani F, Kayvanpour E, Tugrul OF, Lai A, Amr A, Haas J, Proctor T, Ehlermann P, Jensen K, Katus HA, Meder B.
    Clin Res Cardiol; 2018 Jan 01; 107(1):30-41. PubMed ID: 28840316
    [Abstract] [Full Text] [Related]

  • 13. Enhanced myofilament calcium sensitivity aggravates abnormal calcium handling and diastolic dysfunction in patient-specific induced pluripotent stem cell-derived cardiomyocytes with MYH7 mutation.
    Guo G, Wang L, Li X, Fu W, Cao J, Zhang J, Liu Y, Liu M, Wang M, Zhao G, Zhao X, Zhou Y, Niu S, Liu G, Zhang Y, Dong J, Tao H, Zhao X.
    Cell Calcium; 2024 Jan 01; 117():102822. PubMed ID: 38101154
    [Abstract] [Full Text] [Related]

  • 14. MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy.
    O'Leary TS, Snyder J, Sadayappan S, Day SM, Previs MJ.
    J Mol Cell Cardiol; 2019 Feb 01; 127():165-173. PubMed ID: 30550750
    [Abstract] [Full Text] [Related]

  • 15. Microvascular function is selectively impaired in patients with hypertrophic cardiomyopathy and sarcomere myofilament gene mutations.
    Olivotto I, Girolami F, Sciagrà R, Ackerman MJ, Sotgia B, Bos JM, Nistri S, Sgalambro A, Grifoni C, Torricelli F, Camici PG, Cecchi F.
    J Am Coll Cardiol; 2011 Aug 16; 58(8):839-48. PubMed ID: 21835320
    [Abstract] [Full Text] [Related]

  • 16. Prevalence and distribution of sarcomeric gene mutations in Japanese patients with familial hypertrophic cardiomyopathy.
    Otsuka H, Arimura T, Abe T, Kawai H, Aizawa Y, Kubo T, Kitaoka H, Nakamura H, Nakamura K, Okamoto H, Ichida F, Ayusawa M, Nunoda S, Isobe M, Matsuzaki M, Doi YL, Fukuda K, Sasaoka T, Izumi T, Ashizawa N, Kimura A.
    Circ J; 2012 Aug 16; 76(2):453-61. PubMed ID: 22112859
    [Abstract] [Full Text] [Related]

  • 17. Expression patterns of cardiac myofilament proteins: genomic and protein analysis of surgical myectomy tissue from patients with obstructive hypertrophic cardiomyopathy.
    Theis JL, Bos JM, Theis JD, Miller DV, Dearani JA, Schaff HV, Gersh BJ, Ommen SR, Moss RL, Ackerman MJ.
    Circ Heart Fail; 2009 Jul 16; 2(4):325-33. PubMed ID: 19808356
    [Abstract] [Full Text] [Related]

  • 18. Detection of mutations in symptomatic patients with hypertrophic cardiomyopathy in Taiwan.
    Chiou KR, Chu CT, Charng MJ.
    J Cardiol; 2015 Mar 16; 65(3):250-6. PubMed ID: 25086479
    [Abstract] [Full Text] [Related]

  • 19. Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity.
    Memo M, Leung MC, Ward DG, dos Remedios C, Morimoto S, Zhang L, Ravenscroft G, McNamara E, Nowak KJ, Marston SB, Messer AE.
    Cardiovasc Res; 2013 Jul 01; 99(1):65-73. PubMed ID: 23539503
    [Abstract] [Full Text] [Related]

  • 20. Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes.
    Schuldt M, Johnston JR, He H, Huurman R, Pei J, Harakalova M, Poggesi C, Michels M, Kuster DWD, Pinto JR, van der Velden J.
    J Mol Cell Cardiol; 2021 Jan 01; 150():77-90. PubMed ID: 33148509
    [Abstract] [Full Text] [Related]

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