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Journal Abstract Search

210 related items for PubMed ID: 23511419

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  • 3. An improved route to 19-substituted geldanamycins as novel Hsp90 inhibitors--potential therapeutics in cancer and neurodegeneration.
    Kitson RR, Moody CJ.
    Chem Commun (Camb); 2013 Oct 04; 49(76):8441-3. PubMed ID: 23770604
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  • 4. Design, synthesis and biological evaluation of 17-arylmethylamine-17-demethoxygeldanamycin derivatives as potent Hsp90 inhibitors.
    Li Z, Jia L, Wang J, Wu X, Hao H, Xu H, Wu Y, Shi G, Lu C, Shen Y.
    Eur J Med Chem; 2014 Oct 06; 85():359-70. PubMed ID: 25105924
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  • 5. Synthesis of benzoquinone ansamycin-inspired macrocyclic lactams from shikimic acid.
    Jeso V, Iqbal S, Hernandez P, Cameron MD, Park H, LoGrasso PV, Micalizio GC.
    Angew Chem Int Ed Engl; 2013 Apr 26; 52(18):4800-4. PubMed ID: 23554224
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  • 6. Mechanistic studies on Hsp90 inhibition by ansamycin derivatives.
    Onuoha SC, Mukund SR, Coulstock ET, Sengerovà B, Shaw J, McLaughlin SH, Jackson SE.
    J Mol Biol; 2007 Sep 14; 372(2):287-97. PubMed ID: 17662999
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  • 7. Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites.
    Lee K, Ryu JS, Jin Y, Kim W, Kaur N, Chung SJ, Jeon YJ, Park JT, Bang JS, Lee HS, Kim TY, Lee JJ, Hong YS.
    Org Biomol Chem; 2008 Jan 21; 6(2):340-8. PubMed ID: 18175003
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  • 10. Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy.
    Franke J, Eichner S, Zeilinger C, Kirschning A.
    Nat Prod Rep; 2013 Oct 11; 30(10):1299-323. PubMed ID: 23934201
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  • 14. Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.
    Ge J, Normant E, Porter JR, Ali JA, Dembski MS, Gao Y, Georges AT, Grenier L, Pak RH, Patterson J, Sydor JR, Tibbitts TT, Tong JK, Adams J, Palombella VJ.
    J Med Chem; 2006 Jul 27; 49(15):4606-15. PubMed ID: 16854066
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  • 15. Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.
    Kim T, Keum G, Pae AN.
    Expert Opin Ther Pat; 2013 Aug 27; 23(8):919-43. PubMed ID: 23641970
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  • 16. Design, synthesis, and structure--activity relationships for chimeric inhibitors of Hsp90.
    Shen G, Wang M, Welch TR, Blagg BS.
    J Org Chem; 2006 Sep 29; 71(20):7618-31. PubMed ID: 16995666
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  • 17. HSP90 inhibitors: multi-targeted antitumor effects and novel combinatorial therapeutic approaches in cancer therapy.
    Hwang M, Moretti L, Lu B.
    Curr Med Chem; 2009 Sep 29; 16(24):3081-92. PubMed ID: 19689285
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  • 18. Synthesis of reblastatin, autolytimycin, and non-benzoquinone analogues: potent inhibitors of heat shock protein 90.
    Wrona IE, Gozman A, Taldone T, Chiosis G, Panek JS.
    J Org Chem; 2010 May 07; 75(9):2820-35. PubMed ID: 20392070
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  • 19. Learning from nature: advances in geldanamycin- and radicicol-based inhibitors of Hsp90.
    Kitson RR, Moody CJ.
    J Org Chem; 2013 Jun 07; 78(11):5117-41. PubMed ID: 23496136
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  • 20. Conformational significance of EH21A1-A4, phenolic derivatives of geldanamycin, for Hsp90 inhibitory activity.
    Onodera H, Kaneko M, Takahashi Y, Uochi Y, Funahashi J, Nakashima T, Soga S, Suzuki M, Ikeda S, Yamashita Y, Rahayu ES, Kanda Y, Ichimura M.
    Bioorg Med Chem Lett; 2008 Mar 01; 18(5):1588-91. PubMed ID: 18243703
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