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Journal Abstract Search


1837 related items for PubMed ID: 23526220

  • 1. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
    Lin CC, Yeh HH, Huang WL, Yan JJ, Lai WW, Su WP, Chen HH, Su WC.
    Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
    [Abstract] [Full Text] [Related]

  • 2. Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth.
    Rocha GZ, Dias MM, Ropelle ER, Osório-Costa F, Rossato FA, Vercesi AE, Saad MJ, Carvalheira JB.
    Clin Cancer Res; 2011 Jun 15; 17(12):3993-4005. PubMed ID: 21543517
    [Abstract] [Full Text] [Related]

  • 3. SIRT1 and AMPK mediate hypoxia-induced resistance of non-small cell lung cancers to cisplatin and doxorubicin.
    Shin DH, Choi YJ, Park JW.
    Cancer Res; 2014 Jan 01; 74(1):298-308. PubMed ID: 24240701
    [Abstract] [Full Text] [Related]

  • 4. Synergistic effects of metformin treatment in combination with gefitinib, a selective EGFR tyrosine kinase inhibitor, in LKB1 wild-type NSCLC cell lines.
    Morgillo F, Sasso FC, Della Corte CM, Vitagliano D, D'Aiuto E, Troiani T, Martinelli E, De Vita F, Orditura M, De Palma R, Ciardiello F.
    Clin Cancer Res; 2013 Jul 01; 19(13):3508-19. PubMed ID: 23695170
    [Abstract] [Full Text] [Related]

  • 5. Blockage of Stat3 enhances the sensitivity of NSCLC cells to PI3K/mTOR inhibition.
    Jin HO, Lee YH, Park JA, Kim JH, Hong SE, Kim HA, Kim EK, Noh WC, Kim BH, Ye SK, Chang YH, Hong SI, Hong YJ, Park IC, Lee JK.
    Biochem Biophys Res Commun; 2014 Feb 21; 444(4):502-8. PubMed ID: 24472538
    [Abstract] [Full Text] [Related]

  • 6. Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis.
    O'Brien AJ, Villani LA, Broadfield LA, Houde VP, Galic S, Blandino G, Kemp BE, Tsakiridis T, Muti P, Steinberg GR.
    Biochem J; 2015 Jul 15; 469(2):177-87. PubMed ID: 25940306
    [Abstract] [Full Text] [Related]

  • 7. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma.
    Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, Qiu B, Li Y, Guo L, Wu M, Feng G, Zou D, Wang H.
    Clin Cancer Res; 2013 Oct 01; 19(19):5372-80. PubMed ID: 23942093
    [Abstract] [Full Text] [Related]

  • 8. Metformin inhibits growth of human non-small cell lung cancer cells via liver kinase B-1-independent activation of adenosine monophosphate-activated protein kinase.
    Guo Q, Liu Z, Jiang L, Liu M, Ma J, Yang C, Han L, Nan K, Liang X.
    Mol Med Rep; 2016 Mar 01; 13(3):2590-6. PubMed ID: 26847819
    [Abstract] [Full Text] [Related]

  • 9. Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non small cell lung cancer cells.
    Memmott RM, Gills JJ, Hollingshead M, Powers MC, Chen Z, Kemp B, Kozikowski A, Dennis PA.
    Cancer Res; 2008 Jan 15; 68(2):580-8. PubMed ID: 18199555
    [Abstract] [Full Text] [Related]

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  • 11. A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.
    Yeh CT, Huang WC, Rao YK, Ye M, Lee WH, Wang LS, Tzeng DT, Wu CH, Shieh YS, Huang CY, Chen YJ, Hsiao M, Wu AT, Yang Z, Tzeng YM.
    Carcinogenesis; 2013 Dec 15; 34(12):2918-28. PubMed ID: 23880305
    [Abstract] [Full Text] [Related]

  • 12. Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion.
    Yeh HH, Lai WW, Chen HH, Liu HS, Su WC.
    Oncogene; 2006 Jul 20; 25(31):4300-9. PubMed ID: 16518408
    [Abstract] [Full Text] [Related]

  • 13. Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer.
    Dalwadi H, Krysan K, Heuze-Vourc'h N, Dohadwala M, Elashoff D, Sharma S, Cacalano N, Lichtenstein A, Dubinett S.
    Clin Cancer Res; 2005 Nov 01; 11(21):7674-82. PubMed ID: 16278387
    [Abstract] [Full Text] [Related]

  • 14. Metformin inhibits TNF-alpha-induced IkappaB kinase phosphorylation, IkappaB-alpha degradation and IL-6 production in endothelial cells through PI3K-dependent AMPK phosphorylation.
    Huang NL, Chiang SH, Hsueh CH, Liang YJ, Chen YJ, Lai LP.
    Int J Cardiol; 2009 May 15; 134(2):169-75. PubMed ID: 18597869
    [Abstract] [Full Text] [Related]

  • 15. Nootkatone, an AMPK activator derived from grapefruit, inhibits KRAS downstream pathway and sensitizes non-small-cell lung cancer A549 cells to adriamycin.
    Hung LVM, Moon JY, Ryu JY, Cho SK.
    Phytomedicine; 2019 Oct 15; 63():153000. PubMed ID: 31280139
    [Abstract] [Full Text] [Related]

  • 16. Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells.
    Kawashima I, Mitsumori T, Nozaki Y, Yamamoto T, Shobu-Sueki Y, Nakajima K, Kirito K.
    Exp Hematol; 2015 Jul 15; 43(7):524-33.e1. PubMed ID: 25846811
    [Abstract] [Full Text] [Related]

  • 17. Prognostic significance of STAT3 expression and its correlation with chemoresistance of non-small cell lung cancer cells.
    Yin Z, Zhang Y, Li Y, Lv T, Liu J, Wang X.
    Acta Histochem; 2012 Feb 15; 114(2):151-8. PubMed ID: 21549414
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  • 19. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
    Li CM, Narayanan R, Lu Y, Hurh E, Coss CC, Barrett CM, Miller DD, Dalton JT.
    Int J Oncol; 2010 Oct 15; 37(4):1023-30. PubMed ID: 20811725
    [Abstract] [Full Text] [Related]

  • 20. Metformin reduces cisplatin-mediated apoptotic death of cancer cells through AMPK-independent activation of Akt.
    Janjetovic K, Vucicevic L, Misirkic M, Vilimanovich U, Tovilovic G, Zogovic N, Nikolic Z, Jovanovic S, Bumbasirevic V, Trajkovic V, Harhaji-Trajkovic L.
    Eur J Pharmacol; 2011 Jan 25; 651(1-3):41-50. PubMed ID: 21114978
    [Abstract] [Full Text] [Related]


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