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137 related items for PubMed ID: 2353941

  • 21. pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH.
    Sierra EE, Brigle KE, Spinella MJ, Goldman ID.
    Biochem Pharmacol; 1997 Jan 24; 53(2):223-31. PubMed ID: 9037255
    [Abstract] [Full Text] [Related]

  • 22. Relationships between carrier-mediated transport of folate compounds by L1210 leukemia cells: evidence for multiplicity of entry routes with different kinetic properties expressed in plasma membrane vesicles.
    Yang CH, Dembo M, Sirotnak FM.
    J Membr Biol; 1983 Jan 24; 75(1):11-20. PubMed ID: 6887234
    [Abstract] [Full Text] [Related]

  • 23. Identification of cholate as a shared substrate for the unidirectional efflux systems for methotrexate in L1210 mouse cells.
    Henderson GB, Tsuji JM.
    Biochim Biophys Acta; 1990 Jan 23; 1051(1):60-70. PubMed ID: 2297542
    [Abstract] [Full Text] [Related]

  • 24. Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor.
    Theti DS, Bavetsias V, Skelton LA, Titley J, Gibbs D, Jansen G, Jackman AL.
    Cancer Res; 2003 Jul 01; 63(13):3612-8. PubMed ID: 12839949
    [Abstract] [Full Text] [Related]

  • 25. The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Jackman AL, Newell DR, Gibson W, Jodrell DI, Taylor GA, Bishop JA, Hughes LR, Calvert AH.
    Biochem Pharmacol; 1991 Oct 24; 42(10):1885-95. PubMed ID: 1741766
    [Abstract] [Full Text] [Related]

  • 26. Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivo.
    Jackman AL, Taylor GA, O'Connor BM, Bishop JA, Moran RG, Calvert AH.
    Cancer Res; 1990 Sep 01; 50(17):5212-8. PubMed ID: 2386929
    [Abstract] [Full Text] [Related]

  • 27. Effects of folate receptor expression following stable transfection into wild type and methotrexate transport-deficient ZR-75-1 human breast cancer cells.
    Dixon KH, Mulligan T, Chung KN, Elwood PC, Cowan KH.
    J Biol Chem; 1992 Nov 25; 267(33):24140-7. PubMed ID: 1429743
    [Abstract] [Full Text] [Related]

  • 28. Transport of the antitumor antibiotic Cl-920 into L1210 leukemia cells by the reduced folate carrier system.
    Fry DW, Besserer JA, Boritzki TJ.
    Cancer Res; 1984 Aug 25; 44(8):3366-70. PubMed ID: 6547636
    [Abstract] [Full Text] [Related]

  • 29. Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells.
    Sierra EE, Brigle KE, Spinella MJ, Goldman ID.
    Biochem Pharmacol; 1995 Oct 12; 50(8):1287-94. PubMed ID: 7488246
    [Abstract] [Full Text] [Related]

  • 30. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors.
    Jansen G, Schornagel JH, Westerhof GR, Rijksen G, Newell DR, Jackman AL.
    Cancer Res; 1990 Dec 01; 50(23):7544-8. PubMed ID: 2253202
    [Abstract] [Full Text] [Related]

  • 31. ATP-dependent efflux of 2,4-dinitrophenyl-S-glutathione. Properties of two distinct transport systems in inside-out vesicles from L1210 cells and a variant subline with altered efflux of methotrexate and cholate.
    Saxena M, Henderson GB.
    J Biol Chem; 1995 Mar 10; 270(10):5312-9. PubMed ID: 7890643
    [Abstract] [Full Text] [Related]

  • 32. Membrane transport of folate compounds.
    Huennekens FM, Vitols KS, Pope LE, Fan J.
    J Nutr Sci Vitaminol (Tokyo); 1992 Mar 10; Spec No():52-7. PubMed ID: 1297801
    [Abstract] [Full Text] [Related]

  • 33. 5'-Cholesteryl-phosphorothioate oligodeoxynucleotides: potent inhibition of methotrexate transport and antagonism of methotrexate toxicity in cells containing the reduced-folate carrier.
    Henderson GB, Stein CA.
    Nucleic Acids Res; 1995 Sep 25; 23(18):3726-31. PubMed ID: 7479003
    [Abstract] [Full Text] [Related]

  • 34. Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukemia cell extracts.
    Thorndike J, Gaumont Y, Kisliuk RL, Sirotnak FM, Murthy BR, Nair MG, Piper JR.
    Cancer Res; 1989 Jan 01; 49(1):158-63. PubMed ID: 2521177
    [Abstract] [Full Text] [Related]

  • 35. Evidence for a localized conversion of endogenous tetrahydrofolate cofactors to dihydrofolate as an important element in antifolate action in murine leukemia cells.
    Matherly LH, Muench SP.
    Biochem Pharmacol; 1990 Jun 15; 39(12):2005-14. PubMed ID: 2141258
    [Abstract] [Full Text] [Related]

  • 36. Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier.
    Brigle KE, Seither RL, Westin EH, Goldman ID.
    J Biol Chem; 1994 Feb 11; 269(6):4267-72. PubMed ID: 8307991
    [Abstract] [Full Text] [Related]

  • 37. Extent of the requirement for folate transport by L1210 cells for growth and leukemogenesis in vivo.
    Sirotnak FM, Goutas LJ, Mines LS.
    Cancer Res; 1985 Oct 11; 45(10):4732-4. PubMed ID: 3875399
    [Abstract] [Full Text] [Related]

  • 38. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A, Galivan J, Beardsley GP, Bader H, O'Connor BM, Russello O, Moroson BA, DeYarman MT, Kerwar SS, Freisheim JH.
    Cancer Res; 1992 Apr 15; 52(8):2148-55. PubMed ID: 1313737
    [Abstract] [Full Text] [Related]

  • 39. The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate.
    Zhao R, Babani S, Gao F, Liu L, Goldman ID.
    Clin Cancer Res; 2000 Sep 15; 6(9):3687-95. PubMed ID: 10999762
    [Abstract] [Full Text] [Related]

  • 40. Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier.
    Zhao R, Gao F, Goldman ID.
    Biochem Pharmacol; 1999 Nov 15; 58(10):1615-24. PubMed ID: 10535753
    [Abstract] [Full Text] [Related]

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