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318 related items for PubMed ID: 2354436

  • 1. Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
    Kramer DL, Porter CW, Borchardt RT, Sufrin JR.
    Cancer Res; 1990 Jul 01; 50(13):3838-42. PubMed ID: 2354436
    [Abstract] [Full Text] [Related]

  • 2. Elucidation of the mechanism by which homocysteine potentiates the anti-vaccinia virus effects of the S-adenosylhomocysteine hydrolase inhibitor 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine.
    Hasobe M, McKee JG, Ishii H, Cools M, Borchardt RT, De Clercq E.
    Mol Pharmacol; 1989 Sep 01; 36(3):490-6. PubMed ID: 2779528
    [Abstract] [Full Text] [Related]

  • 3. Effects of 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine on the metabolism of S-adenosylhomocysteine in mouse L929 cells.
    Hasobe M, Mckee JG, Borcherding DR, Keller BT, Borchardt RT.
    Mol Pharmacol; 1988 Jun 01; 33(6):713-20. PubMed ID: 2454388
    [Abstract] [Full Text] [Related]

  • 4. Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation.
    Hermes M, Geisler H, Osswald H, Riehle R, Kloor D.
    Biochem Pharmacol; 2008 Jun 01; 75(11):2100-11. PubMed ID: 18395186
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  • 7. Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
    Huang Y, Komoto J, Konishi K, Takata Y, Ogawa H, Gomi T, Fujioka M, Takusagawa F.
    J Mol Biol; 2000 Apr 21; 298(1):149-62. PubMed ID: 10756111
    [Abstract] [Full Text] [Related]

  • 8. Effects of adenosine dialdehyde on S-adenosylhomocysteine hydrolase and S-adenosylmethionine-dependent transmethylations in mouse L929 cells.
    Bartel RL, Borchardt RT.
    Mol Pharmacol; 1984 May 21; 25(3):418-24. PubMed ID: 6727864
    [Abstract] [Full Text] [Related]

  • 9. Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes.
    Møller MT, Samari HR, Fengsrud M, Strømhaug PE, øStvold AC, Seglen PO.
    Biochem J; 2003 Jul 15; 373(Pt 2):505-13. PubMed ID: 12697024
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of transmethylation disturbs neurulation in chick embryos.
    Afman LA, Blom HJ, Drittij MJ, Brouns MR, van Straaten HW.
    Brain Res Dev Brain Res; 2005 Aug 08; 158(1-2):59-65. PubMed ID: 15996755
    [Abstract] [Full Text] [Related]

  • 11. S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
    Hershfield MS, Kredich NM, Koller CA, Mitchell BS, Kurtzberg J, Kinney TR, Falletta JM.
    Cancer Res; 1983 Jul 08; 43(7):3451-8. PubMed ID: 6601986
    [Abstract] [Full Text] [Related]

  • 12. Apoptosis and transmethylation metabolites in HL-60 cells.
    Endresen PC, Loennechen T, Kildalsen H, Aarbakke J.
    J Pharmacol Exp Ther; 1996 Sep 08; 278(3):1318-24. PubMed ID: 8819518
    [Abstract] [Full Text] [Related]

  • 13. Relative effects of S-adenosylmethionine depletion on nucleic acid methylation and polyamine biosynthesis.
    Kramer DL, Sufrin JR, Porter CW.
    Biochem J; 1987 Oct 15; 247(2):259-65. PubMed ID: 3426538
    [Abstract] [Full Text] [Related]

  • 14. Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
    Shivapurkar N, Poirier LA.
    Carcinogenesis; 1983 Aug 15; 4(8):1051-7. PubMed ID: 6872150
    [Abstract] [Full Text] [Related]

  • 15. The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
    Gill MW, Schatz RA.
    Res Commun Chem Pathol Pharmacol; 1985 Dec 15; 50(3):349-63. PubMed ID: 4081323
    [Abstract] [Full Text] [Related]

  • 16. S-adenosylmethionine synthetase is overexpressed in murine neuroblastoma cells resistant to nucleoside analogue inhibitors of S-adenosylhomocysteine hydrolase: a novel mechanism of drug resistance.
    Dwivedi RS, Wang LJ, Mirkin BL.
    Cancer Res; 1999 Apr 15; 59(8):1852-6. PubMed ID: 10213491
    [Abstract] [Full Text] [Related]

  • 17. Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism.
    Svardal AM, Djurhuus R, Refsum H, Ueland PM.
    Cancer Res; 1986 Oct 15; 46(10):5095-100. PubMed ID: 3756867
    [Abstract] [Full Text] [Related]

  • 18. S-Adenosylmethionine and S-adenosylhomocystein metabolism in isolated rat liver. Effects of L-methionine, L-homocystein, and adenosine.
    Hoffman DR, Marion DW, Cornatzer WE, Duerre JA.
    J Biol Chem; 1980 Nov 25; 255(22):10822-7. PubMed ID: 7430157
    [Abstract] [Full Text] [Related]

  • 19. Relationship between intracellular concentration of S-adenosylhomocysteine and inhibition of vaccinia virus replication and inhibition of murine L-929 cell growth.
    Hasobe M, McKee JG, Borchardt RT.
    Antimicrob Agents Chemother; 1989 Jun 25; 33(6):828-34. PubMed ID: 2764532
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of the impact of S-adenosylhomocysteine metabolic pools on cytosine methylation of the tobacco genome.
    Fojtová M, Kovarík A, Votruba I, Holý A.
    Eur J Biochem; 1998 Mar 15; 252(3):347-52. PubMed ID: 9546648
    [Abstract] [Full Text] [Related]

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