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1093 related items for PubMed ID: 23546866

  • 1. Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis.
    Ahn J, Won M, Choi JH, Kim YS, Jung CR, Im DS, Kyun ML, Lee K, Song KB, Chung KS.
    Apoptosis; 2013 Jul; 18(7):870-81. PubMed ID: 23546866
    [Abstract] [Full Text] [Related]

  • 2. Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells.
    Kuo PL, Chen CY, Hsu YL.
    Cancer Res; 2007 Aug 01; 67(15):7406-20. PubMed ID: 17671211
    [Abstract] [Full Text] [Related]

  • 3. Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways.
    Chen Y, Zheng L, Liu J, Zhou Z, Cao X, Lv X, Chen F.
    Int Immunopharmacol; 2014 Aug 01; 21(2):447-55. PubMed ID: 24905636
    [Abstract] [Full Text] [Related]

  • 4. Clostridium difficile toxin A-induced colonocyte apoptosis involves p53-dependent p21(WAF1/CIP1) induction via p38 mitogen-activated protein kinase.
    Kim H, Kokkotou E, Na X, Rhee SH, Moyer MP, Pothoulakis C, Lamont JT.
    Gastroenterology; 2005 Dec 01; 129(6):1875-88. PubMed ID: 16344056
    [Abstract] [Full Text] [Related]

  • 5. Reactive oxygen species-activated Akt/ASK1/p38 signaling pathway in nickel compound-induced apoptosis in BEAS 2B cells.
    Pan J, Chang Q, Wang X, Son Y, Zhang Z, Chen G, Luo J, Bi Y, Chen F, Shi X.
    Chem Res Toxicol; 2010 Mar 15; 23(3):568-77. PubMed ID: 20112989
    [Abstract] [Full Text] [Related]

  • 6. Induction of p21(Waf1/Cip1) by garcinol via downregulation of p38-MAPK signaling in p53-independent H1299 lung cancer.
    Yu SY, Liao CH, Chien MH, Tsai TY, Lin JK, Weng MS.
    J Agric Food Chem; 2014 Mar 05; 62(9):2085-95. PubMed ID: 24533688
    [Abstract] [Full Text] [Related]

  • 7. BBR induces apoptosis in HepG2 cell through an Akt-ASK1-ROS-p38MAPKs-linked cascade.
    Hyun MS, Hur JM, Mun YJ, Kim D, Woo WH.
    J Cell Biochem; 2010 Feb 01; 109(2):329-38. PubMed ID: 19950206
    [Abstract] [Full Text] [Related]

  • 8. DDTD, an isoflavone derivative, induces cell apoptosis through the reactive oxygen species/apoptosis signal-regulating kinase 1 pathway in human osteosarcoma cells.
    Chen JT, Fong YC, Li TM, Liu JF, Hsu CW, Chang CS, Tang CH.
    Eur J Pharmacol; 2008 Nov 12; 597(1-3):19-26. PubMed ID: 18822283
    [Abstract] [Full Text] [Related]

  • 9. Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells.
    Ouyang M, Shen X.
    J Neurochem; 2006 Apr 12; 97(1):234-44. PubMed ID: 16515547
    [Abstract] [Full Text] [Related]

  • 10. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Apr 12; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 11. Role of apoptosis signal-regulating kinase 1 in complement-mediated glomerular epithelial cell injury.
    Ren G, Huynh C, Bijian K, Cybulsky AV.
    Mol Immunol; 2008 Apr 12; 45(8):2236-46. PubMed ID: 18178252
    [Abstract] [Full Text] [Related]

  • 12. Apoptosis signal-regulating kinase 1-mediated sustained p38 mitogen-activated protein kinase activation regulates mycoplasmal lipoprotein- and staphylococcal peptidoglycan-triggered Toll-like receptor 2 signalling pathways.
    Into T, Shibata K.
    Cell Microbiol; 2005 Sep 12; 7(9):1305-17. PubMed ID: 16098218
    [Abstract] [Full Text] [Related]

  • 13. Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).
    Meng LH, Kohn KW, Pommier Y.
    Oncogene; 2007 Jul 19; 26(33):4806-16. PubMed ID: 17297446
    [Abstract] [Full Text] [Related]

  • 14. Activation of the p38 MAPK/Akt/ERK1/2 signal pathways is required for the protein stabilization of CDC6 and cyclin D1 in low-dose arsenite-induced cell proliferation.
    Liu Y, Hock JM, Sullivan C, Fang G, Cox AJ, Davis KT, Davis BH, Li X.
    J Cell Biochem; 2010 Dec 15; 111(6):1546-55. PubMed ID: 20862710
    [Abstract] [Full Text] [Related]

  • 15. Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation.
    Asada M, Yamada T, Ichijo H, Delia D, Miyazono K, Fukumuro K, Mizutani S.
    EMBO J; 1999 Mar 01; 18(5):1223-34. PubMed ID: 10064589
    [Abstract] [Full Text] [Related]

  • 16. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.
    Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL.
    Cancer Lett; 2008 Jan 18; 259(1):82-98. PubMed ID: 18023967
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.
    Mochizuki T, Furuta S, Mitsushita J, Shang WH, Ito M, Yokoo Y, Yamaura M, Ishizone S, Nakayama J, Konagai A, Hirose K, Kiyosawa K, Kamata T.
    Oncogene; 2006 Jun 22; 25(26):3699-707. PubMed ID: 16532036
    [Abstract] [Full Text] [Related]

  • 18. Obatoclax induces G1/G0-phase arrest via p38/p21(waf1/Cip1) signaling pathway in human esophageal cancer cells.
    Zhong D, Gu C, Shi L, Xun T, Li X, Liu S, Yu L.
    J Cell Biochem; 2014 Sep 22; 115(9):1624-35. PubMed ID: 24788582
    [Abstract] [Full Text] [Related]

  • 19. Heat shock protein 27 protects L929 cells from cisplatin-induced apoptosis by enhancing Akt activation and abating suppression of thioredoxin reductase activity.
    Zhang Y, Shen X.
    Clin Cancer Res; 2007 May 15; 13(10):2855-64. PubMed ID: 17504983
    [Abstract] [Full Text] [Related]

  • 20. Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells.
    Cordero-Herrera I, Martín MA, Bravo L, Goya L, Ramos S.
    Nutr Cancer; 2013 May 15; 65(5):718-28. PubMed ID: 23859040
    [Abstract] [Full Text] [Related]

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