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Journal Abstract Search

266 related items for PubMed ID: 23562731

  • 1. The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop.
    Forsman H, Bylund J, Oprea TI, Karlsson A, Boulay F, Rabiet MJ, Dahlgren C.
    Biochim Biophys Acta; 2013 Aug; 1833(8):1914-23. PubMed ID: 23562731
    [Abstract] [Full Text] [Related]

  • 2. A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead.
    Winther M, Gabl M, Welin A, Dahlgren C, Forsman H.
    FEBS Lett; 2015 Jul 08; 589(15):1832-9. PubMed ID: 26071379
    [Abstract] [Full Text] [Related]

  • 3. A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism.
    Gabl M, Holdfeldt A, Winther M, Oprea T, Bylund J, Dahlgren C, Forsman H.
    Biochim Biophys Acta; 2016 Jun 08; 1863(6 Pt A):1228-37. PubMed ID: 26996596
    [Abstract] [Full Text] [Related]

  • 4. Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question.
    Winther M, Holdfeldt A, Sundqvist M, Rajabkhani Z, Gabl M, Bylund J, Dahlgren C, Forsman H.
    PLoS One; 2017 Jun 08; 12(9):e0185132. PubMed ID: 28934373
    [Abstract] [Full Text] [Related]

  • 5. Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin.
    Forsman H, Andréasson E, Karlsson J, Boulay F, Rabiet MJ, Dahlgren C.
    J Immunol; 2012 Jul 15; 189(2):629-37. PubMed ID: 22706076
    [Abstract] [Full Text] [Related]

  • 6. A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2.
    Gabl M, Winther M, Skovbakke SL, Bylund J, Dahlgren C, Forsman H.
    PLoS One; 2014 Jul 15; 9(10):e109516. PubMed ID: 25303226
    [Abstract] [Full Text] [Related]

  • 7. Peptide length and folding state govern the capacity of staphylococcal β-type phenol-soluble modulins to activate human formyl-peptide receptors 1 or 2.
    Kretschmer D, Rautenberg M, Linke D, Peschel A.
    J Leukoc Biol; 2015 Apr 15; 97(4):689-97. PubMed ID: 25724390
    [Abstract] [Full Text] [Related]

  • 8. The PAR4-derived pepducin P4Pal10 lacks effect on neutrophil GPCRs that couple to Gαq for signaling but distinctly modulates function of the Gαi-coupled FPR2 and FFAR2.
    Holdfeldt A, Lind S, Hesse C, Dahlgren C, Forsman H.
    Biochem Pharmacol; 2020 Oct 15; 180():114143. PubMed ID: 32653592
    [Abstract] [Full Text] [Related]

  • 9. A membrane-tethering pepducin that inhibits formyl peptide receptor 2-induced signaling.
    Lee HY, Kim H, Lee SY, Jung YS, Kim SD, Bae YS.
    Pharmazie; 2014 Apr 15; 69(4):293-6. PubMed ID: 24791594
    [Abstract] [Full Text] [Related]

  • 10. FPR2 signaling without β-arrestin recruitment alters the functional repertoire of neutrophils.
    Gabl M, Holdfeldt A, Sundqvist M, Lomei J, Dahlgren C, Forsman H.
    Biochem Pharmacol; 2017 Dec 01; 145():114-122. PubMed ID: 28855087
    [Abstract] [Full Text] [Related]

  • 11. The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels.
    Karlsson J, Stenfeldt AL, Rabiet MJ, Bylund J, Forsman HF, Dahlgren C.
    Cell Calcium; 2009 May 01; 45(5):431-8. PubMed ID: 19282028
    [Abstract] [Full Text] [Related]

  • 12. Mitocryptide-2: Identification of Its Minimum Structure for Specific Activation of FPR2-Possible Receptor Switching from FPR2 to FPR1 by Its Physiological C-terminal Cleavages.
    Marutani T, Nishino K, Miyaji T, Kamada K, Ohura K, Kiso Y, Mukai H.
    Int J Mol Sci; 2021 Apr 15; 22(8):. PubMed ID: 33920954
    [Abstract] [Full Text] [Related]

  • 13. Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group.
    Forsman H, Winther M, Gabl M, Skovbakke SL, Boulay F, Rabiet MJ, Dahlgren C.
    Biochim Biophys Acta; 2015 Jan 15; 1853(1):192-200. PubMed ID: 25447672
    [Abstract] [Full Text] [Related]

  • 14. Identification of C-terminal phosphorylation sites of N-formyl peptide receptor-1 (FPR1) in human blood neutrophils.
    Maaty WS, Lord CI, Gripentrog JM, Riesselman M, Keren-Aviram G, Liu T, Dratz EA, Bothner B, Jesaitis AJ.
    J Biol Chem; 2013 Sep 20; 288(38):27042-27058. PubMed ID: 23873933
    [Abstract] [Full Text] [Related]

  • 15. The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2.
    Skovbakke SL, Heegaard PM, Larsen CJ, Franzyk H, Forsman H, Dahlgren C.
    Biochem Pharmacol; 2015 Jan 15; 93(2):182-95. PubMed ID: 25462815
    [Abstract] [Full Text] [Related]

  • 16. Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria.
    Dahlgren C, Gabl M, Holdfeldt A, Winther M, Forsman H.
    Biochem Pharmacol; 2016 Aug 15; 114():22-39. PubMed ID: 27131862
    [Abstract] [Full Text] [Related]

  • 17. Antibacterial activity of pepducins, allosterical modulators of formyl peptide receptor signaling.
    Winther M, Gabl M, Oprea TI, Jönsson B, Boulay F, Bylund J, Dahlgren C, Forsman H.
    Antimicrob Agents Chemother; 2014 May 15; 58(5):2985-8. PubMed ID: 24590483
    [Abstract] [Full Text] [Related]

  • 18. Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.
    Schepetkin IA, Kirpotina LN, Khlebnikov AI, Jutila MA, Quinn MT.
    Mol Pharmacol; 2011 Jan 15; 79(1):77-90. PubMed ID: 20943772
    [Abstract] [Full Text] [Related]

  • 19. Structural Determinants in the Staphylococcus aureus-Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation.
    Viklund M, Fredriksson J, Holdfeldt A, Lind S, Franzyk H, Dahlgren C, Sundqvist M, Forsman H.
    J Immunol; 2022 Apr 01; 208(7):1632-1641. PubMed ID: 35321878
    [Abstract] [Full Text] [Related]

  • 20. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands.
    He HQ, Troksa EL, Caltabiano G, Pardo L, Ye RD.
    J Biol Chem; 2014 Jan 24; 289(4):2295-306. PubMed ID: 24285541
    [Abstract] [Full Text] [Related]

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