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158 related items for PubMed ID: 23570653

  • 1. Silibinin inhibits tumor growth through downregulation of extracellular signal-regulated kinase and Akt in vitro and in vivo in human ovarian cancer cells.
    Cho HJ, Suh DS, Moon SH, Song YJ, Yoon MS, Park DY, Choi KU, Kim YK, Kim KH.
    J Agric Food Chem; 2013 May 01; 61(17):4089-96. PubMed ID: 23570653
    [Abstract] [Full Text] [Related]

  • 2. Silibinin induces cell death through reactive oxygen species-dependent downregulation of notch-1/ERK/Akt signaling in human breast cancer cells.
    Kim TH, Woo JS, Kim YK, Kim KH.
    J Pharmacol Exp Ther; 2014 May 01; 349(2):268-78. PubMed ID: 24472723
    [Abstract] [Full Text] [Related]

  • 3. Silibinin inhibits glioma cell proliferation via Ca2+/ROS/MAPK-dependent mechanism in vitro and glioma tumor growth in vivo.
    Kim KW, Choi CH, Kim TH, Kwon CH, Woo JS, Kim YK.
    Neurochem Res; 2009 Aug 01; 34(8):1479-90. PubMed ID: 19263218
    [Abstract] [Full Text] [Related]

  • 4. Lycii cortex radicis extract inhibits glioma tumor growth in vitro and in vivo through downregulation of the Akt/ERK pathway.
    Jeong JC, Kim SJ, Kim YK, Kwon CH, Kim KH.
    Oncol Rep; 2012 May 01; 27(5):1467-74. PubMed ID: 22266745
    [Abstract] [Full Text] [Related]

  • 5. Kaempferol induces cell death through ERK and Akt-dependent down-regulation of XIAP and survivin in human glioma cells.
    Jeong JC, Kim MS, Kim TH, Kim YK.
    Neurochem Res; 2009 May 01; 34(5):991-1001. PubMed ID: 18949556
    [Abstract] [Full Text] [Related]

  • 6. The adenosine A3 receptor agonist Cl-IB-MECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells.
    Kim TH, Kim YK, Woo JS.
    Neurochem Res; 2012 Dec 01; 37(12):2667-77. PubMed ID: 22878643
    [Abstract] [Full Text] [Related]

  • 7. Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
    Mallikarjuna G, Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R.
    Cancer Res; 2004 Sep 01; 64(17):6349-56. PubMed ID: 15342425
    [Abstract] [Full Text] [Related]

  • 8. Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma.
    Li L, Gao Y, Zhang L, Zeng J, He D, Sun Y.
    Cancer Lett; 2008 Dec 08; 272(1):61-9. PubMed ID: 18723275
    [Abstract] [Full Text] [Related]

  • 9. Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis.
    Singh RP, Tyagi AK, Zhao J, Agarwal R.
    Carcinogenesis; 2002 Mar 08; 23(3):499-510. PubMed ID: 11895866
    [Abstract] [Full Text] [Related]

  • 10. Inhibitory effect of silibinin on EGFR signal-induced renal cell carcinoma progression via suppression of the EGFR/MMP-9 signaling pathway.
    Liang L, Li L, Zeng J, Gao Y, Chen YL, Wang ZQ, Wang XY, Chang LS, He D.
    Oncol Rep; 2012 Sep 08; 28(3):999-1005. PubMed ID: 22736024
    [Abstract] [Full Text] [Related]

  • 11. Interruption of mitochondrial complex IV activity and cytochrome c expression activated O₂·⁻-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways.
    Jiang YY, Huang H, Wang HJ, Wu D, Yang R, Tashiro S, Onodera S, Ikejima T.
    Eur J Pharmacol; 2011 Oct 01; 668(1-2):78-87. PubMed ID: 21703257
    [Abstract] [Full Text] [Related]

  • 12. Mulberry fruit (Moris fructus) extracts induce human glioma cell death in vitro through ROS-dependent mitochondrial pathway and inhibits glioma tumor growth in vivo.
    Jeong JC, Jang SW, Kim TH, Kwon CH, Kim YK.
    Nutr Cancer; 2010 Oct 01; 62(3):402-12. PubMed ID: 20358478
    [Abstract] [Full Text] [Related]

  • 13. Deltonin induces apoptosis in MDA‑MB‑231 human breast cancer cells via reactive oxygen species‑mediated mitochondrial dysfunction and ERK/AKT signaling pathways.
    Zhang S, He Y, Tong Q, Chen Q, Wu X, Huang W.
    Mol Med Rep; 2013 Mar 01; 7(3):1038-44. PubMed ID: 23314115
    [Abstract] [Full Text] [Related]

  • 14. Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway.
    Momeny M, Ghasemi R, Valenti G, Miranda M, Zekri A, Zarrinrad G, Javadikooshesh S, Yaghmaie M, Alimoghaddam K, Ghavamzadeh A, Ghaffari SH.
    Tumour Biol; 2016 Mar 01; 37(3):3913-23. PubMed ID: 26482609
    [Abstract] [Full Text] [Related]

  • 15. Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells.
    Liu B, Yang P, Ye Y, Zhou Y, Li L, Tashiro S, Onodera S, Ikejima T.
    Free Radic Res; 2011 Jul 01; 45(7):835-47. PubMed ID: 21568648
    [Abstract] [Full Text] [Related]

  • 16. Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy.
    Singh RP, Dhanalakshmi S, Agarwal C, Agarwal R.
    Oncogene; 2005 Feb 10; 24(7):1188-202. PubMed ID: 15558015
    [Abstract] [Full Text] [Related]

  • 17. Silibinin protects H9c2 cardiac cells from oxidative stress and inhibits phenylephrine-induced hypertrophy: potential mechanisms.
    Anestopoulos I, Kavo A, Tentes I, Kortsaris A, Panayiotidis M, Lazou A, Pappa A.
    J Nutr Biochem; 2013 Mar 10; 24(3):586-94. PubMed ID: 22818713
    [Abstract] [Full Text] [Related]

  • 18. Silibinin-induced glioma cell apoptosis by PI3K-mediated but Akt-independent downregulation of FoxM1 expression.
    Zhang M, Liu Y, Gao Y, Li S.
    Eur J Pharmacol; 2015 Oct 15; 765():346-54. PubMed ID: 26342429
    [Abstract] [Full Text] [Related]

  • 19. Underlying mechanism of quercetin-induced cell death in human glioma cells.
    Kim EJ, Choi CH, Park JY, Kang SK, Kim YK.
    Neurochem Res; 2008 Jun 15; 33(6):971-9. PubMed ID: 18322795
    [Abstract] [Full Text] [Related]

  • 20. Silibinin induces apoptosis through inhibition of the mTOR-GLI1-BCL2 pathway in renal cell carcinoma.
    Ma Z, Liu W, Zeng J, Zhou J, Guo P, Xie H, Yang Z, Zheng L, Xu S, Wang X, Chang LS, He D, Li L.
    Oncol Rep; 2015 Nov 15; 34(5):2461-8. PubMed ID: 26323996
    [Abstract] [Full Text] [Related]


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