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Journal Abstract Search

236 related items for PubMed ID: 23580643

  • 1. Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes.
    Nakamura T, Aizawa T, Kariya R, Okada S, Demura M, Kawano K, Makabe K, Kuwajima K.
    J Biol Chem; 2013 May 17; 288(20):14408-14416. PubMed ID: 23580643
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  • 2. Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.
    Mossberg AK, Hun Mok K, Morozova-Roche LA, Svanborg C.
    FEBS J; 2010 Nov 17; 277(22):4614-25. PubMed ID: 20977665
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  • 3. alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.
    Pettersson J, Mossberg AK, Svanborg C.
    Biochem Biophys Res Commun; 2006 Jun 23; 345(1):260-70. PubMed ID: 16678133
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  • 4. alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.
    Pettersson-Kastberg J, Mossberg AK, Trulsson M, Yong YJ, Min S, Lim Y, O'Brien JE, Svanborg C, Mok KH.
    J Mol Biol; 2009 Dec 18; 394(5):994-1010. PubMed ID: 19766653
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  • 5. Applications of site-specific labeling to study HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.
    Mercer N, Ramakrishnan B, Boeggeman E, Qasba PK.
    PLoS One; 2011 Dec 18; 6(10):e26093. PubMed ID: 22016817
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  • 6. Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death.
    Ho JC, Storm P, Rydström A, Bowen B, Alsin F, Sullivan L, Ambite I, Mok KH, Northen T, Svanborg C.
    J Biol Chem; 2013 Jun 14; 288(24):17460-71. PubMed ID: 23629662
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  • 7. Compact oleic acid in HAMLET.
    Fast J, Mossberg AK, Nilsson H, Svanborg C, Akke M, Linse S.
    FEBS Lett; 2005 Nov 07; 579(27):6095-100. PubMed ID: 16229842
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  • 9. Structure and Potential Cellular Targets of HAMLET-like Anti-Cancer Compounds made from Milk Components.
    Rath EM, Duff AP, Håkansson AP, Vacher CS, Liu GJ, Knott RB, Church WB.
    J Pharm Pharm Sci; 2015 Nov 07; 18(4):773-824. PubMed ID: 26626257
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  • 14. A novel method for preparation of HAMLET-like protein complexes.
    Permyakov SE, Knyazeva EL, Leonteva MV, Fadeev RS, Chekanov AV, Zhadan AP, Håkansson AP, Akatov VS, Permyakov EA.
    Biochimie; 2011 Sep 07; 93(9):1495-501. PubMed ID: 21596091
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  • 15. Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications.
    Xie Y, Min S, Harte NP, Kirk H, O'Brien JE, Voorheis HP, Svanborg C, Hun Mok K.
    Proteins; 2013 Jan 07; 81(1):1-17. PubMed ID: 22777854
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  • 16. Oleic acid is a key cytotoxic component of HAMLET-like complexes.
    Permyakov SE, Knyazeva EL, Khasanova LM, Fadeev RS, Zhadan AP, Roche-Hakansson H, Håkansson AP, Akatov VS, Permyakov EA.
    Biol Chem; 2012 Jan 07; 393(1-2):85-92. PubMed ID: 22628302
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  • 17. Lipids as cofactors in protein folding: stereo-specific lipid-protein interactions are required to form HAMLET (human alpha-lactalbumin made lethal to tumor cells).
    Svensson M, Mossberg AK, Pettersson J, Linse S, Svanborg C.
    Protein Sci; 2003 Dec 07; 12(12):2805-14. PubMed ID: 14627740
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  • 19. HAMLET in human milk is resistant to digestion and carries essential free long chain polyunsaturated fatty acids and oleic acid.
    Chetta KE, Forconi M, Newton DA, Wagner CL, Baatz JE.
    Food Chem; 2023 Nov 30; 427():136752. PubMed ID: 37392621
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  • 20. Cytotoxicity of bovine α-lactalbumin: oleic acid complexes correlates with the disruption of lipid membranes.
    Wen H, Glomm WR, Halskau O.
    Biochim Biophys Acta; 2013 Nov 30; 1828(11):2691-9. PubMed ID: 23916586
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