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Journal Abstract Search

231 related items for PubMed ID: 23584048

  • 1. Analytical power of LLE-HPLC-PDA-MS/MS in drug metabolism studies: identification of new nabumetone metabolites.
    Nobilis M, Mikušek J, Szotáková B, Jirásko R, Holčapek M, Chamseddin C, Jira T, Kučera R, Kuneš J, Pour M.
    J Pharm Biomed Anal; 2013 Jun; 80():164-72. PubMed ID: 23584048
    [Abstract] [Full Text] [Related]

  • 2. Role of human flavin-containing monooxygenase (FMO) 5 in the metabolism of nabumetone: Baeyer-Villiger oxidation in the activation of the intermediate metabolite, 3-hydroxy nabumetone, to the active metabolite, 6-methoxy-2-naphthylacetic acid in vitro.
    Matsumoto K, Hasegawa T, Ohara K, Kamei T, Koyanagi J, Akimoto M.
    Xenobiotica; 2021 Feb; 51(2):155-166. PubMed ID: 33146575
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  • 3. A metabolic pathway for the prodrug nabumetone to the pharmacologically active metabolite, 6-methoxy-2-naphthylacetic acid (6-MNA) by non-cytochrome P450 enzymes.
    Matsumoto K, Hasegawa T, Ohara K, Takei C, Kamei T, Koyanagi J, Takahashi T, Akimoto M.
    Xenobiotica; 2020 Jul; 50(7):783-792. PubMed ID: 31855101
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  • 4. Comparative biotransformation and disposition studies of nabumetone in humans and minipigs using high-performance liquid chromatography with ultraviolet, fluorescence and mass spectrometric detection.
    Nobilis M, Kopecký J, Kvetina J, Svoboda Z, Pour M, Kunes J, Holcapek M, Kolárová L.
    J Pharm Biomed Anal; 2003 Aug 08; 32(4-5):641-56. PubMed ID: 12899954
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  • 6. [Determination of nabumetone and 6-methoxy-2-naphthylacetic acid in plasma using HPLC with UV and MS detection].
    Nespesná L, Stícha M, Matousková O, Perlík F, Slanar O.
    Ceska Slov Farm; 2011 Feb 08; 60(1):17-24. PubMed ID: 21650014
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  • 11. [Determination of 6-methoxy-2-naphthylacetic acid, a major metabolite of nabumetone, in human plasma by HPLC].
    Qin Y, Zou Y, Liang M, Huang Y, Yu Q.
    Hua Xi Yi Ke Da Xue Xue Bao; 1999 Dec 08; 30(4):452-4. PubMed ID: 11387968
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  • 12. A novel injection strategy of flurbiprofen axetil by inhibiting protein binding with 6-methoxy-2-naphthylacetic acid.
    Ogata K, Takamura N, Tokunaga J, Ikeda T, Setoguchi N, Tanda K, Yamasaki T, Nishio T, Kawai K.
    Eur J Drug Metab Pharmacokinet; 2016 Apr 08; 41(2):179-86. PubMed ID: 25537338
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  • 13. Disposition and excretion of 6-methoxy-2-naphthylacetic acid, the active metabolite of nabumetone in horses.
    Soma LR, Uboh CE, Rudy JA, Smith MS.
    Am J Vet Res; 1996 Apr 08; 57(4):517-21. PubMed ID: 8712517
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  • 14. Simultaneous analysis of naproxen, nabumetone and its major metabolite 6-methoxy-2-naphthylacetic acid in pharmaceuticals and human urine by high-performance liquid chromatography.
    Mikami E, Goto T, Ohno T, Matsumoto H, Nishida M.
    J Pharm Biomed Anal; 2000 Oct 08; 23(5):917-25. PubMed ID: 11022916
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  • 15. Nonsteroidal anti-inflammatory drug therapy and gastric side effects. Does nabumetone provide a solution?
    Dandona P, Jeremy JY.
    Drugs; 1990 Oct 08; 40 Suppl 5():16-24. PubMed ID: 2081487
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  • 17. Carbon-carbon bond cleavage in activation of the prodrug nabumetone.
    Varfaj F, Zulkifli SN, Park HG, Challinor VL, De Voss JJ, Ortiz de Montellano PR.
    Drug Metab Dispos; 2014 May 08; 42(5):828-38. PubMed ID: 24584631
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  • 18. Nabumetone. Evidence for the lack of enterohepatic circulation of the active metabolite 6-MNA in humans.
    Brett MA, Buscher G, Ellrich E, Greb WH, Kurth HJ, Rülander G, Schmerenbeck B, Haddock RE, Thawley AR.
    Drugs; 1990 May 08; 40 Suppl 5():67-70. PubMed ID: 2081498
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  • 19. Role of carbonyl reducing enzymes in the phase I biotransformation of the non-steroidal anti-inflammatory drug nabumetone in vitro.
    Skarydova L, Nobilis M, Wsól V.
    Xenobiotica; 2013 Apr 08; 43(4):346-54. PubMed ID: 23020786
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  • 20. Extractionless determination of 6-methoxy-2-naphthylacetic acid, a major metabolite of nabumetone, in human plasma by high-performance liquid chromatography.
    de Jager AD, Hundt HK, Hundt AF, Swart KJ, Knight M, Roberts J.
    J Chromatogr B Biomed Sci Appl; 2000 Apr 14; 740(2):247-51. PubMed ID: 10821411
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