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Journal Abstract Search

478 related items for PubMed ID: 23597704

  • 1. Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases.
    Tan CY, Hagen T.
    Int J Biochem Cell Biol; 2013 Jul; 45(7):1489-98. PubMed ID: 23597704
    [Abstract] [Full Text] [Related]

  • 2. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
    Lan H, Tang Z, Jin H, Sun Y.
    Sci Rep; 2016 Apr 11; 6():24218. PubMed ID: 27063292
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of NEDD8-activating enzyme induces rereplication and apoptosis in human tumor cells consistent with deregulating CDT1 turnover.
    Milhollen MA, Narayanan U, Soucy TA, Veiby PO, Smith PG, Amidon B.
    Cancer Res; 2011 Apr 15; 71(8):3042-51. PubMed ID: 21487042
    [Abstract] [Full Text] [Related]

  • 4. Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage.
    Hall JR, Kow E, Nevis KR, Lu CK, Luce KS, Zhong Q, Cook JG.
    Mol Biol Cell; 2007 Sep 15; 18(9):3340-50. PubMed ID: 17567951
    [Abstract] [Full Text] [Related]

  • 5. Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization.
    Chew EH, Poobalasingam T, Hawkey CJ, Hagen T.
    Cell Signal; 2007 May 15; 19(5):1071-80. PubMed ID: 17254749
    [Abstract] [Full Text] [Related]

  • 6. Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.
    Luo Z, Pan Y, Jeong LS, Liu J, Jia L.
    Autophagy; 2012 Nov 15; 8(11):1677-9. PubMed ID: 22874562
    [Abstract] [Full Text] [Related]

  • 7. Suppression of glioblastoma by targeting the overactivated protein neddylation pathway.
    Hua W, Li C, Yang Z, Li L, Jiang Y, Yu G, Zhu W, Liu Z, Duan S, Chu Y, Yang M, Zhang Y, Mao Y, Jia L.
    Neuro Oncol; 2015 Oct 15; 17(10):1333-43. PubMed ID: 25904638
    [Abstract] [Full Text] [Related]

  • 8. CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway.
    Saito N, Sakakibara K, Sato T, Friedman JM, Kufe DW, VonHoff DD, Kawabe T.
    Mol Cancer Ther; 2014 Dec 15; 13(12):3013-23. PubMed ID: 25253782
    [Abstract] [Full Text] [Related]

  • 9. NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells.
    Lin JJ, Milhollen MA, Smith PG, Narayanan U, Dutta A.
    Cancer Res; 2010 Dec 15; 70(24):10310-20. PubMed ID: 21159650
    [Abstract] [Full Text] [Related]

  • 10. Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
    Larance M, Kirkwood KJ, Xirodimas DP, Lundberg E, Uhlen M, Lamond AI.
    Mol Cell Proteomics; 2012 Mar 15; 11(3):M111.014407. PubMed ID: 22038470
    [Abstract] [Full Text] [Related]

  • 11. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
    Yao WT, Wu JF, Yu GY, Wang R, Wang K, Li LH, Chen P, Jiang YN, Cheng H, Lee HW, Yu J, Qi H, Yu XJ, Wang P, Chu YW, Yang M, Hua ZC, Ying HQ, Hoffman RM, Jeong LS, Jia LJ.
    Cell Death Dis; 2014 Feb 13; 5(2):e1059. PubMed ID: 24525735
    [Abstract] [Full Text] [Related]

  • 12. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.
    Wang Y, Luo Z, Pan Y, Wang W, Zhou X, Jeong LS, Chu Y, Liu J, Jia L.
    Cancer Biol Ther; 2015 Feb 13; 16(3):420-9. PubMed ID: 25782162
    [Abstract] [Full Text] [Related]

  • 13. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
    Bornstein G, Ganoth D, Hershko A.
    Proc Natl Acad Sci U S A; 2006 Aug 01; 103(31):11515-20. PubMed ID: 16861300
    [Abstract] [Full Text] [Related]

  • 14. Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy.
    Zhao Y, Morgan MA, Sun Y.
    Antioxid Redox Signal; 2014 Dec 10; 21(17):2383-400. PubMed ID: 24410571
    [Abstract] [Full Text] [Related]

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  • 17. Norcantharidin promotes cancer radiosensitization through Cullin1 neddylation-mediated CDC6 protein degradation.
    Deng T, Zhu Q, Xie L, Liu Y, Peng Y, Yin L, Gao Y, Cao T, Fu Y, Qi X, Zhang S, Peng Y, Hou Y, Li X.
    Mol Carcinog; 2022 Aug 10; 61(8):812-824. PubMed ID: 35652616
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  • 20. Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer.
    Pan WW, Zhou JJ, Yu C, Xu Y, Guo LJ, Zhang HY, Zhou D, Song FZ, Fan HY.
    J Biol Chem; 2013 Oct 11; 288(41):29680-91. PubMed ID: 23995842
    [Abstract] [Full Text] [Related]

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