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5. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1. Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC. Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261 [Abstract] [Full Text] [Related]
6. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP. J Neurosci; 2008 Oct 08; 28(41):10234-44. PubMed ID: 18842883 [Abstract] [Full Text] [Related]
7. Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1. Tokuda E, Okawa E, Watanabe S, Ono S. Hum Mol Genet; 2014 Mar 01; 23(5):1271-85. PubMed ID: 24163136 [Abstract] [Full Text] [Related]
9. A truncating SOD1 mutation, p.Gly141X, is associated with clinical and pathologic heterogeneity, including frontotemporal lobar degeneration. Nakamura M, Bieniek KF, Lin WL, Graff-Radford NR, Murray ME, Castanedes-Casey M, Desaro P, Baker MC, Rutherford NJ, Robertson J, Rademakers R, Dickson DW, Boylan KB. Acta Neuropathol; 2015 Jul 01; 130(1):145-57. PubMed ID: 25917047 [Abstract] [Full Text] [Related]
10. Galectin-1 deficiency improves axonal swelling of motor neurones in SOD1(G93A) transgenic mice. Kobayakawa Y, Sakumi K, Kajitani K, Kadoya T, Horie H, Kira J, Nakabeppu Y. Neuropathol Appl Neurobiol; 2015 Feb 01; 41(2):227-44. PubMed ID: 24707896 [Abstract] [Full Text] [Related]
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13. Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease. Nagai M, Aoki M, Miyoshi I, Kato M, Pasinelli P, Kasai N, Brown RH, Itoyama Y. J Neurosci; 2001 Dec 01; 21(23):9246-54. PubMed ID: 11717358 [Abstract] [Full Text] [Related]
14. Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation. Peviani M, Salvaneschi E, Bontempi L, Petese A, Manzo A, Rossi D, Salmona M, Collina S, Bigini P, Curti D. Neurobiol Dis; 2014 Feb 01; 62():218-32. PubMed ID: 24141020 [Abstract] [Full Text] [Related]
15. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. Science; 2003 Oct 03; 302(5642):113-7. PubMed ID: 14526083 [Abstract] [Full Text] [Related]
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19. Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice. Qiu L, Qiao T, Beers M, Tan W, Wang H, Yang B, Xu Z. Mol Neurodegener; 2013 Jan 03; 8():1. PubMed ID: 23281774 [Abstract] [Full Text] [Related]
20. Mitochondrial dysfunction and its role in motor neuron degeneration in ALS. Manfredi G, Xu Z. Mitochondrion; 2005 Apr 03; 5(2):77-87. PubMed ID: 16050975 [Abstract] [Full Text] [Related] Page: [Next] [New Search]