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222 related items for PubMed ID: 23612977

  • 1. NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells.
    Yang J, Singh V, Cha B, Chen TE, Sarker R, Murtazina R, Jin S, Zachos NC, Patterson GH, Tse CM, Kovbasnjuk O, Li X, Donowitz M.
    J Biol Chem; 2013 Jun 07; 288(23):16960-16974. PubMed ID: 23612977
    [Abstract] [Full Text] [Related]

  • 2. NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol.
    Yang J, Singh V, Chen TE, Sarker R, Xiong L, Cha B, Jin S, Li X, Tse CM, Zachos NC, Donowitz M.
    J Biol Chem; 2014 Jul 18; 289(29):20039-53. PubMed ID: 24867958
    [Abstract] [Full Text] [Related]

  • 3. Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling.
    Cha B, Chen T, Sarker R, Yang J, Raben D, Tse CM, Kovbasnjuk O, Donowitz M.
    Am J Physiol Cell Physiol; 2014 Jul 01; 307(1):C55-65. PubMed ID: 24760985
    [Abstract] [Full Text] [Related]

  • 4. Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca2+, cGMP, and lysophosphatidic acid.
    Avula LR, Chen T, Kovbasnjuk O, Donowitz M.
    Am J Physiol Gastrointest Liver Physiol; 2018 Jan 01; 314(1):G81-G90. PubMed ID: 28882822
    [Abstract] [Full Text] [Related]

  • 5. NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid.
    Cha B, Zhu XC, Chen W, Jones M, Ryoo S, Zachos NC, Chen TE, Lin R, Sarker R, Kenworthy AK, Tse M, Kovbasnjuk O, Donowitz M.
    J Cell Sci; 2010 Jul 15; 123(Pt 14):2434-43. PubMed ID: 20571054
    [Abstract] [Full Text] [Related]

  • 6. D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process.
    Lin R, Murtazina R, Cha B, Chakraborty M, Sarker R, Chen TE, Lin Z, Hogema BM, de Jonge HR, Seidler U, Turner JR, Li X, Kovbasnjuk O, Donowitz M.
    Gastroenterology; 2011 Feb 15; 140(2):560-71. PubMed ID: 20977906
    [Abstract] [Full Text] [Related]

  • 7. NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.
    Sarker R, Valkhoff VE, Zachos NC, Lin R, Cha B, Chen TE, Guggino S, Zizak M, de Jonge H, Hogema B, Donowitz M.
    Am J Physiol Cell Physiol; 2011 Apr 15; 300(4):C771-82. PubMed ID: 21191106
    [Abstract] [Full Text] [Related]

  • 8. The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP.
    Cha B, Kenworthy A, Murtazina R, Donowitz M.
    J Cell Sci; 2004 Jul 01; 117(Pt 15):3353-65. PubMed ID: 15226406
    [Abstract] [Full Text] [Related]

  • 9. Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 proteins in opossum kidney (OK) cell microvilli.
    Zhu X, Cha B, Zachos NC, Sarker R, Chakraborty M, Chen TE, Kovbasnjuk O, Donowitz M.
    J Biol Chem; 2011 Oct 07; 286(40):34486-96. PubMed ID: 21799002
    [Abstract] [Full Text] [Related]

  • 10. The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity.
    Yang J, Sarker R, Singh V, Sarker P, Yin J, Chen TE, Chaerkady R, Li X, Tse CM, Donowitz M.
    Biochem J; 2015 Aug 15; 470(1):77-90. PubMed ID: 26251448
    [Abstract] [Full Text] [Related]

  • 11. Differential association of the Na+/H+ Exchanger Regulatory Factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3.
    Sultan A, Luo M, Yu Q, Riederer B, Xia W, Chen M, Lissner S, Gessner JE, Donowitz M, Yun CC, deJonge H, Lamprecht G, Seidler U.
    Cell Physiol Biochem; 2013 Aug 15; 32(5):1386-402. PubMed ID: 24297041
    [Abstract] [Full Text] [Related]

  • 12. Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism.
    Zachos NC, Hodson C, Kovbasnjuk O, Li X, Thelin WR, Cha B, Milgram S, Donowitz M.
    Cell Physiol Biochem; 2008 Aug 15; 22(5-6):693-704. PubMed ID: 19088451
    [Abstract] [Full Text] [Related]

  • 13. The epithelial brush border Na+/H+ exchanger NHE3 associates with the actin cytoskeleton by binding to ezrin directly and via PDZ domain-containing Na+/H+ exchanger regulatory factor (NHERF) proteins.
    Cha B, Donowitz M.
    Clin Exp Pharmacol Physiol; 2008 Aug 15; 35(8):863-71. PubMed ID: 18430067
    [Abstract] [Full Text] [Related]

  • 14. Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK.
    Wade JB, Welling PA, Donowitz M, Shenolikar S, Weinman EJ.
    Am J Physiol Cell Physiol; 2001 Jan 15; 280(1):C192-8. PubMed ID: 11121391
    [Abstract] [Full Text] [Related]

  • 15. Na+-H+ exchanger regulatory factor 1 (NHERF1) PDZ scaffold binds an internal binding site in the scavenger receptor megalin.
    Slattery C, Jenkin KA, Lee A, Simcocks AC, McAinch AJ, Poronnik P, Hryciw DH.
    Cell Physiol Biochem; 2011 Jan 15; 27(2):171-8. PubMed ID: 21325834
    [Abstract] [Full Text] [Related]

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  • 17. Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells.
    Weinman EJ, Steplock D, Wade JB, Shenolikar S.
    Am J Physiol Renal Physiol; 2001 Aug 15; 281(2):F374-80. PubMed ID: 11457730
    [Abstract] [Full Text] [Related]

  • 18. NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum.
    Murtazina R, Kovbasnjuk O, Chen TE, Zachos NC, Chen Y, Kocinsky HS, Hogema BM, Seidler U, de Jonge HR, Donowitz M.
    Am J Physiol Cell Physiol; 2011 Jul 15; 301(1):C126-36. PubMed ID: 21430287
    [Abstract] [Full Text] [Related]

  • 19. Regulation of albumin endocytosis by PSD95/Dlg/ZO-1 (PDZ) scaffolds. Interaction of Na+-H+ exchange regulatory factor-2 with ClC-5.
    Hryciw DH, Ekberg J, Ferguson C, Lee A, Wang D, Parton RG, Pollock CA, Yun CC, Poronnik P.
    J Biol Chem; 2006 Jun 09; 281(23):16068-77. PubMed ID: 16601121
    [Abstract] [Full Text] [Related]

  • 20. Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2.
    Lin S, Yeruva S, He P, Singh AK, Zhang H, Chen M, Lamprecht G, de Jonge HR, Tse M, Donowitz M, Hogema BM, Chun J, Seidler U, Yun CC.
    Gastroenterology; 2010 Feb 09; 138(2):649-58. PubMed ID: 19800338
    [Abstract] [Full Text] [Related]

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