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Journal Abstract Search


274 related items for PubMed ID: 23620398

  • 1. Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.
    Sun H, Schlondorff J, Higgs HN, Pollak MR.
    J Am Soc Nephrol; 2013 May; 24(6):917-29. PubMed ID: 23620398
    [Abstract] [Full Text] [Related]

  • 2. Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2).
    Sun H, Schlondorff JS, Brown EJ, Higgs HN, Pollak MR.
    Proc Natl Acad Sci U S A; 2011 Feb 15; 108(7):2933-8. PubMed ID: 21278336
    [Abstract] [Full Text] [Related]

  • 3. Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury.
    Subramanian B, Sun H, Yan P, Charoonratana VT, Higgs HN, Wang F, Lai KV, Valenzuela DM, Brown EJ, Schlöndorff JS, Pollak MR.
    Kidney Int; 2016 Aug 15; 90(2):363-372. PubMed ID: 27350175
    [Abstract] [Full Text] [Related]

  • 4. Role of formin INF2 in human diseases.
    Zhao Y, Zhang H, Wang H, Ye M, Jin X.
    Mol Biol Rep; 2022 Jan 15; 49(1):735-746. PubMed ID: 34698992
    [Abstract] [Full Text] [Related]

  • 5. FSGS-Causing INF2 Mutation Impairs Cleaved INF2 N-Fragment Functions in Podocytes.
    Subramanian B, Chun J, Perez-Gill C, Yan P, Stillman IE, Higgs HN, Alper SL, Schlöndorff JS, Pollak MR.
    J Am Soc Nephrol; 2020 Feb 15; 31(2):374-391. PubMed ID: 31924668
    [Abstract] [Full Text] [Related]

  • 6. Dysregulated Dynein-Mediated Trafficking of Nephrin Causes INF2-related Podocytopathy.
    Sun H, Perez-Gill C, Schlöndorff JS, Subramanian B, Pollak MR.
    J Am Soc Nephrol; 2021 Feb 15; 32(2):307-322. PubMed ID: 33443052
    [Abstract] [Full Text] [Related]

  • 7. Novel mutations in the inverted formin 2 gene of Chinese families contribute to focal segmental glomerulosclerosis.
    Xie J, Hao X, Azeloglu EU, Ren H, Wang Z, Ma J, Liu J, Ma X, Wang W, Pan X, Zhang W, Zhong F, Li Y, Meng G, Kiryluk K, He JC, Gharavi AG, Chen N.
    Kidney Int; 2015 Sep 15; 88(3):593-604. PubMed ID: 26039629
    [Abstract] [Full Text] [Related]

  • 8. Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2.
    Rollason R, Wherlock M, Heath JA, Heesom KJ, Saleem MA, Welsh GI.
    Biosci Rep; 2016 Jan 13; 36(1):e00302. PubMed ID: 26764407
    [Abstract] [Full Text] [Related]

  • 9. Mutations to the formin homology 2 domain of INF2 protein have unexpected effects on actin polymerization and severing.
    Ramabhadran V, Gurel PS, Higgs HN.
    J Biol Chem; 2012 Oct 05; 287(41):34234-45. PubMed ID: 22879592
    [Abstract] [Full Text] [Related]

  • 10. Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus.
    Sun H, Al-Romaih KI, MacRae CA, Pollak MR.
    EBioMedicine; 2014 Dec 05; 1(2-3):107-15. PubMed ID: 26086034
    [Abstract] [Full Text] [Related]

  • 11. A complex containing lysine-acetylated actin inhibits the formin INF2.
    A M, Fung TS, Kettenbach AN, Chakrabarti R, Higgs HN.
    Nat Cell Biol; 2019 May 05; 21(5):592-602. PubMed ID: 30962575
    [Abstract] [Full Text] [Related]

  • 12. Actin monomers activate inverted formin 2 by competing with its autoinhibitory interaction.
    Ramabhadran V, Hatch AL, Higgs HN.
    J Biol Chem; 2013 Sep 13; 288(37):26847-55. PubMed ID: 23921379
    [Abstract] [Full Text] [Related]

  • 13. New Paradigm for Cytoskeletal Organization in Podocytes: Proteolytic Fragments of INF2 Formin Function Independently of INF2 Actin Regulatory Activity.
    Krendel M, Pruyne D.
    J Am Soc Nephrol; 2020 Feb 13; 31(2):235-236. PubMed ID: 31924669
    [No Abstract] [Full Text] [Related]

  • 14. Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis.
    Brown EJ, Schlöndorff JS, Becker DJ, Tsukaguchi H, Tonna SJ, Uscinski AL, Higgs HN, Henderson JM, Pollak MR.
    Nat Genet; 2010 Jan 13; 42(1):72-6. PubMed ID: 20023659
    [Abstract] [Full Text] [Related]

  • 15. DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation.
    Schneider R, Deutsch K, Hoeprich GJ, Marquez J, Hermle T, Braun DA, Seltzsam S, Kitzler TM, Mao Y, Buerger F, Majmundar AJ, Onuchic-Whitford AC, Kolvenbach CM, Schierbaum L, Schneider S, Halawi AA, Nakayama M, Mann N, Connaughton DM, Klämbt V, Wagner M, Riedhammer KM, Renders L, Katsura Y, Thumkeo D, Soliman NA, Mane S, Lifton RP, Shril S, Khokha MK, Hoefele J, Goode BL, Hildebrandt F.
    Am J Hum Genet; 2020 Dec 03; 107(6):1113-1128. PubMed ID: 33232676
    [Abstract] [Full Text] [Related]

  • 16. Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin.
    Venkatareddy M, Cook L, Abuarquob K, Verma R, Garg P.
    PLoS One; 2011 Dec 03; 6(12):e28710. PubMed ID: 22194892
    [Abstract] [Full Text] [Related]

  • 17. Mutations in INF2 are a major cause of autosomal dominant focal segmental glomerulosclerosis.
    Boyer O, Benoit G, Gribouval O, Nevo F, Tête MJ, Dantal J, Gilbert-Dussardier B, Touchard G, Karras A, Presne C, Grunfeld JP, Legendre C, Joly D, Rieu P, Mohsin N, Hannedouche T, Moal V, Gubler MC, Broutin I, Mollet G, Antignac C.
    J Am Soc Nephrol; 2011 Feb 03; 22(2):239-45. PubMed ID: 21258034
    [Abstract] [Full Text] [Related]

  • 18. INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy.
    Boyer O, Nevo F, Plaisier E, Funalot B, Gribouval O, Benoit G, Huynh Cong E, Arrondel C, Tête MJ, Montjean R, Richard L, Karras A, Pouteil-Noble C, Balafrej L, Bonnardeaux A, Canaud G, Charasse C, Dantal J, Deschenes G, Deteix P, Dubourg O, Petiot P, Pouthier D, Leguern E, Guiochon-Mantel A, Broutin I, Gubler MC, Saunier S, Ronco P, Vallat JM, Alonso MA, Antignac C, Mollet G.
    N Engl J Med; 2011 Dec 22; 365(25):2377-88. PubMed ID: 22187985
    [Abstract] [Full Text] [Related]

  • 19. The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1).
    Chen A, Arora PD, Lai CC, Copeland JW, Moraes TF, McCulloch CA, Lavoie BD, Wilde A.
    J Biol Chem; 2020 Mar 06; 295(10):3134-3147. PubMed ID: 32005666
    [Abstract] [Full Text] [Related]

  • 20. An mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells.
    Bartolini F, Andres-Delgado L, Qu X, Nik S, Ramalingam N, Kremer L, Alonso MA, Gundersen GG.
    Mol Biol Cell; 2016 Jun 01; 27(11):1797-808. PubMed ID: 27030671
    [Abstract] [Full Text] [Related]


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