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222 related items for PubMed ID: 23633549
1. Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB. Uebelhoer M, Nätynki M, Kangas J, Mendola A, Nguyen HL, Soblet J, Godfraind C, Boon LM, Eklund L, Limaye N, Vikkula M. Hum Mol Genet; 2013 Sep 01; 22(17):3438-48. PubMed ID: 23633549 [Abstract] [Full Text] [Related]
2. AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations. Si Y, Huang J, Li X, Fu Y, Xu R, Du Y, Cheng J, Jiang H. Cell Commun Signal; 2020 Aug 31; 18(1):139. PubMed ID: 32867785 [Abstract] [Full Text] [Related]
3. Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression. Hu HT, Huang YH, Chang YA, Lee CK, Jiang MJ, Wu LW. J Invest Dermatol; 2008 Sep 31; 128(9):2325-33. PubMed ID: 18401423 [Abstract] [Full Text] [Related]
4. Review of the endothelial pathogenic mechanism of TIE2-related venous malformation. Du Z, Zheng J, Zhang Z, Wang Y. J Vasc Surg Venous Lymphat Disord; 2017 Sep 31; 5(5):740-748. PubMed ID: 28818232 [Abstract] [Full Text] [Related]
5. STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production. Huang YH, Wu MP, Pan SC, Su WC, Chen YW, Wu LW. Angiogenesis; 2013 Jan 31; 16(1):207-22. PubMed ID: 23086340 [Abstract] [Full Text] [Related]
6. Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malformations. Limaye N, Wouters V, Uebelhoer M, Tuominen M, Wirkkala R, Mulliken JB, Eklund L, Boon LM, Vikkula M. Nat Genet; 2009 Jan 31; 41(1):118-24. PubMed ID: 19079259 [Abstract] [Full Text] [Related]
10. Common and specific effects of TIE2 mutations causing venous malformations. Nätynki M, Kangas J, Miinalainen I, Sormunen R, Pietilä R, Soblet J, Boon LM, Vikkula M, Limaye N, Eklund L. Hum Mol Genet; 2015 Nov 15; 24(22):6374-89. PubMed ID: 26319232 [Abstract] [Full Text] [Related]
11. Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations. Morris PN, Dunmore BJ, Tadros A, Marchuk DA, Darland DC, D'Amore PA, Brindle NP. J Mol Med (Berl); 2005 Jan 15; 83(1):58-63. PubMed ID: 15526080 [Abstract] [Full Text] [Related]
12. Constitutive Active Mutant TIE2 Induces Enlarged Vascular Lumen Formation with Loss of Apico-basal Polarity and Pericyte Recruitment. Cai Y, Schrenk S, Goines J, Davis GE, Boscolo E. Sci Rep; 2019 Aug 26; 9(1):12352. PubMed ID: 31451744 [Abstract] [Full Text] [Related]
13. A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity. Kennedy MA, Xu Z, Wu Y, Sohl CD. Biochem Biophys Res Commun; 2019 Feb 19; 509(4):898-902. PubMed ID: 30638931 [Abstract] [Full Text] [Related]
14. Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1. Fukuhara S, Sako K, Minami T, Noda K, Kim HZ, Kodama T, Shibuya M, Takakura N, Koh GY, Mochizuki N. Nat Cell Biol; 2008 May 19; 10(5):513-26. PubMed ID: 18425120 [Abstract] [Full Text] [Related]
15. Transgenic Expression of A Venous Malformation Related Mutation, TIE2-R849W, Significantly Induces Multiple Malformations of Zebrafish. Du Z, Ma HL, Zhang ZY, Zheng JW, Wang YA. Int J Med Sci; 2018 May 19; 15(4):385-394. PubMed ID: 29511374 [Abstract] [Full Text] [Related]
16. Lipid rafts serve as signaling platforms for Tie2 receptor tyrosine kinase in vascular endothelial cells. Katoh SY, Kamimoto T, Yamakawa D, Takakura N. Exp Cell Res; 2009 Oct 01; 315(16):2818-23. PubMed ID: 19615361 [Abstract] [Full Text] [Related]
17. Hereditary cutaneomucosal venous malformations are caused by TIE2 mutations with widely variable hyper-phosphorylating effects. Wouters V, Limaye N, Uebelhoer M, Irrthum A, Boon LM, Mulliken JB, Enjolras O, Baselga E, Berg J, Dompmartin A, Ivarsson SA, Kangesu L, Lacassie Y, Murphy J, Teebi AS, Penington A, Rieu P, Vikkula M. Eur J Hum Genet; 2010 Apr 01; 18(4):414-20. PubMed ID: 19888299 [Abstract] [Full Text] [Related]
18. Mutant Tie2 causing venous malformation signals through Shc. Morris PN, Dunmore BJ, Brindle NP. Biochem Biophys Res Commun; 2006 Jul 21; 346(1):335-8. PubMed ID: 16756945 [Abstract] [Full Text] [Related]
19. Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells. Daly C, Pasnikowski E, Burova E, Wong V, Aldrich TH, Griffiths J, Ioffe E, Daly TJ, Fandl JP, Papadopoulos N, McDonald DM, Thurston G, Yancopoulos GD, Rudge JS. Proc Natl Acad Sci U S A; 2006 Oct 17; 103(42):15491-6. PubMed ID: 17030814 [Abstract] [Full Text] [Related]
20. A xenograft model for venous malformation. Goines J, Li X, Cai Y, Mobberley-Schuman P, Metcalf M, Fishman SJ, Adams DM, Hammill AM, Boscolo E. Angiogenesis; 2018 Nov 17; 21(4):725-735. PubMed ID: 29786783 [Abstract] [Full Text] [Related] Page: [Next] [New Search]