These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Phospho-valproic acid (MDC-1112) reduces pancreatic cancer growth in patient-derived tumor xenografts and KPC mice: enhanced efficacy when combined with gemcitabine. Luo D, Digiovanni MG, Wei R, Lacomb JF, Williams JL, Rigas B, Mackenzie GG. Carcinogenesis; 2020 Jul 14; 41(7):927-939. PubMed ID: 31584613 [Abstract] [Full Text] [Related]
4. A novel Ras inhibitor (MDC-1016) reduces human pancreatic tumor growth in mice. Mackenzie GG, Bartels LE, Xie G, Papayannis I, Alston N, Vrankova K, Ouyang N, Rigas B. Neoplasia; 2013 Oct 14; 15(10):1184-95. PubMed ID: 24204197 [Abstract] [Full Text] [Related]
5. Phospho-valproic acid inhibits pancreatic cancer growth in mice: enhanced efficacy by its formulation in poly-(L)-lactic acid-poly(ethylene glycol) nanoparticles. Mattheolabakis G, Wang R, Rigas B, Mackenzie GG. Int J Oncol; 2017 Oct 14; 51(4):1035-1044. PubMed ID: 28849098 [Abstract] [Full Text] [Related]
9. Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro. Zhu WQ, Wang J, Guo XF, Liu Z, Dong WG. World J Gastroenterol; 2016 Apr 28; 22(16):4149-59. PubMed ID: 27122665 [Abstract] [Full Text] [Related]
10. Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells. Pathania D, Kuang Y, Sechi M, Neamati N. Br J Pharmacol; 2015 Jan 28; 172(1):50-63. PubMed ID: 25047070 [Abstract] [Full Text] [Related]
11. Mitochondrial ROS accumulation inhibiting JAK2/STAT3 pathway is a critical modulator of CYT997-induced autophagy and apoptosis in gastric cancer. Cao Y, Wang J, Tian H, Fu GH. J Exp Clin Cancer Res; 2020 Jun 23; 39(1):119. PubMed ID: 32576206 [Abstract] [Full Text] [Related]
15. Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells. Huang S, Sinicrope FA. Mol Cancer Ther; 2010 Mar 23; 9(3):742-50. PubMed ID: 20197401 [Abstract] [Full Text] [Related]
16. Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer. Kasiappan R, Jutooru I, Karki K, Hedrick E, Safe S. J Biol Chem; 2016 Dec 30; 291(53):27122-27133. PubMed ID: 27875298 [Abstract] [Full Text] [Related]
17. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells. Lin L, Hutzen B, Li PK, Ball S, Zuo M, DeAngelis S, Foust E, Sobo M, Friedman L, Bhasin D, Cen L, Li C, Lin J. Neoplasia; 2010 Jan 30; 12(1):39-50. PubMed ID: 20072652 [Abstract] [Full Text] [Related]
18. Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. Liu CY, Su JC, Ni MH, Tseng LM, Chu PY, Wang DS, Tai WT, Kao YP, Hung MH, Shiau CW, Chen KF. Breast Cancer Res Treat; 2014 Jul 30; 146(1):71-84. PubMed ID: 24903225 [Abstract] [Full Text] [Related]
19. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors. Cai G, Yu W, Song D, Zhang W, Guo J, Zhu J, Ren Y, Kong L. Eur J Med Chem; 2019 Jul 15; 174():236-251. PubMed ID: 31048139 [Abstract] [Full Text] [Related]
20. Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma. Sahu N, Chan E, Chu F, Pham T, Koeppen H, Forrest W, Merchant M, Settleman J. Mol Cancer Ther; 2017 Sep 15; 16(9):1729-1738. PubMed ID: 28619758 [Abstract] [Full Text] [Related] Page: [Next] [New Search]