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183 related items for PubMed ID: 23666879
1. A toxicity risk index, an index for warning idiosyncratic drug toxicity. Morimoto M, Samizo K, Ohta S, Mizuma T. J Pharm Sci; 2013 Sep; 102(9):3447-50. PubMed ID: 23666879 [Abstract] [Full Text] [Related]
3. Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States. Stepan AF, Walker DP, Bauman J, Price DA, Baillie TA, Kalgutkar AS, Aleo MD. Chem Res Toxicol; 2011 Sep 19; 24(9):1345-410. PubMed ID: 21702456 [Abstract] [Full Text] [Related]
5. Idiosyncratic toxicity: a convergence of risk factors. Ulrich RG. Annu Rev Med; 2007 Sep 19; 58():17-34. PubMed ID: 16958561 [Abstract] [Full Text] [Related]
6. A Survey of Neonatal Pharmacokinetic and Pharmacodynamic Studies in Pediatric Drug Development. Wang J, Avant D, Green D, Seo S, Fisher J, Mulberg AE, McCune SK, Burckart GJ. Clin Pharmacol Ther; 2015 Sep 19; 98(3):328-35. PubMed ID: 25975723 [Abstract] [Full Text] [Related]
9. In vitro evaluation of the potential for drug-induced toxicity based on (35)S-labeled glutathione adduct formation and daily dose. Miyaji Y, Makino C, Kurihara A, Suzuki W, Okazaki O. Bioanalysis; 2012 Feb 19; 4(3):263-9. PubMed ID: 22303830 [Abstract] [Full Text] [Related]
10. Predicting toxicities of reactive metabolite-positive drug candidates. Kalgutkar AS, Dalvie D. Annu Rev Pharmacol Toxicol; 2015 Feb 19; 55():35-54. PubMed ID: 25292426 [Abstract] [Full Text] [Related]
12. Detecting reactive drug metabolites for reducing the potential for drug toxicity. Grillo MP. Expert Opin Drug Metab Toxicol; 2015 Feb 19; 11(8):1281-302. PubMed ID: 26005795 [Abstract] [Full Text] [Related]
15. [FOOD - DRUG INTERACTIONS: TYPES AND MECHANISMS.]. Lemina EY, Churyukanov VV. Eksp Klin Farmakol; 2016 Feb 19; 79(11):41-44. PubMed ID: 29791108 [Abstract] [Full Text] [Related]
16. Idiosyncratic toxicity: the role of toxicophores and bioactivation. Williams DP, Park BK. Drug Discov Today; 2003 Nov 15; 8(22):1044-50. PubMed ID: 14690635 [Abstract] [Full Text] [Related]
17. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Walgren JL, Mitchell MD, Thompson DC. Crit Rev Toxicol; 2005 Nov 15; 35(4):325-61. PubMed ID: 15989140 [Abstract] [Full Text] [Related]
18. Should the incorporation of structural alerts be restricted in drug design? An analysis of structure-toxicity trends with aniline-based drugs. Kalgutkar AS. Curr Med Chem; 2015 Nov 15; 22(4):438-64. PubMed ID: 25388012 [Abstract] [Full Text] [Related]
20. Drugs in control samples in nonclinical safety studies: a reconsideration. Zimmer D. Bioanalysis; 2016 May 15; 8(10):1003-7. PubMed ID: 27080047 [No Abstract] [Full Text] [Related] Page: [Next] [New Search]