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566 related items for PubMed ID: 23669278

  • 1. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo.
    Wang X, Wu D, Yang L, Gan L, Cederbaum AI.
    Free Radic Biol Med; 2013 Oct; 63():175-86. PubMed ID: 23669278
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.
    Wu D, Cederbaum AI.
    Redox Biol; 2013 Oct; 1(1):552-65. PubMed ID: 24273738
    [Abstract] [Full Text] [Related]

  • 3. Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice.
    Lu Y, Wu D, Wang X, Ward SC, Cederbaum AI.
    Free Radic Biol Med; 2010 Nov 15; 49(9):1406-16. PubMed ID: 20692331
    [Abstract] [Full Text] [Related]

  • 4. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1.
    Lu Y, Cederbaum AI.
    Toxicol Sci; 2006 Feb 15; 89(2):515-23. PubMed ID: 16251482
    [Abstract] [Full Text] [Related]

  • 5. Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy.
    Wu D, Wang X, Zhou R, Yang L, Cederbaum AI.
    Free Radic Biol Med; 2012 Sep 15; 53(6):1346-57. PubMed ID: 22819980
    [Abstract] [Full Text] [Related]

  • 6. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity.
    Cederbaum AI.
    Dig Dis; 2010 Sep 15; 28(6):802-11. PubMed ID: 21525766
    [Abstract] [Full Text] [Related]

  • 7. Autophagy Protects against CYP2E1/Chronic Ethanol-Induced Hepatotoxicity.
    Lu Y, Cederbaum AI.
    Biomolecules; 2015 Oct 16; 5(4):2659-74. PubMed ID: 26501338
    [Abstract] [Full Text] [Related]

  • 8. CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis.
    Abdelmegeed MA, Banerjee A, Jang S, Yoo SH, Yun JW, Gonzalez FJ, Keshavarzian A, Song BJ.
    Free Radic Biol Med; 2013 Dec 16; 65():1238-1245. PubMed ID: 24064383
    [Abstract] [Full Text] [Related]

  • 9. Binge alcohol promotes hypoxic liver injury through a CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans.
    Yun JW, Son MJ, Abdelmegeed MA, Banerjee A, Morgan TR, Yoo SH, Song BJ.
    Free Radic Biol Med; 2014 Dec 16; 77():183-94. PubMed ID: 25236742
    [Abstract] [Full Text] [Related]

  • 10. Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB.
    Román J, Colell A, Blasco C, Caballeria J, Parés A, Rodés J, Fernández-Checa JC.
    Hepatology; 1999 Dec 16; 30(6):1473-80. PubMed ID: 10573527
    [Abstract] [Full Text] [Related]

  • 11. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
    Gong P, Cederbaum AI, Nieto N.
    Mol Pharmacol; 2004 Jan 16; 65(1):130-8. PubMed ID: 14722244
    [Abstract] [Full Text] [Related]

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  • 13. Nrf2 and antioxidant defense against CYP2E1 toxicity.
    Cederbaum A.
    Expert Opin Drug Metab Toxicol; 2009 Oct 16; 5(10):1223-44. PubMed ID: 19671018
    [Abstract] [Full Text] [Related]

  • 14. Nrf2 and antioxidant defense against CYP2E1 toxicity.
    Cederbaum AI.
    Subcell Biochem; 2013 Oct 16; 67():105-30. PubMed ID: 23400918
    [Abstract] [Full Text] [Related]

  • 15. Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
    Gong P, Cederbaum AI, Nieto N.
    Free Radic Biol Med; 2004 Feb 01; 36(3):307-18. PubMed ID: 15036350
    [Abstract] [Full Text] [Related]

  • 16. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase.
    Wang X, Lu Y, Xie B, Cederbaum AI.
    Free Radic Biol Med; 2009 Sep 01; 47(5):518-28. PubMed ID: 19477265
    [Abstract] [Full Text] [Related]

  • 17. CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment.
    Cederbaum AI.
    Drug Metabol Drug Interact; 2012 Sep 01; 27(3):125-44. PubMed ID: 23104821
    [Abstract] [Full Text] [Related]

  • 18. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity.
    Wu D, Cederbaum A.
    Mol Pharmacol; 2004 Sep 01; 66(3):749-60. PubMed ID: 15322268
    [Abstract] [Full Text] [Related]

  • 19. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway.
    Gong P, Cederbaum AI, Nieto N.
    J Biol Chem; 2003 Aug 08; 278(32):29693-700. PubMed ID: 12777398
    [Abstract] [Full Text] [Related]

  • 20. Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity.
    Pérez MJ, Cederbaum AI.
    Free Radic Biol Med; 2003 Feb 15; 34(4):443-55. PubMed ID: 12566070
    [Abstract] [Full Text] [Related]

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