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Journal Abstract Search


248 related items for PubMed ID: 23688082

  • 1. Acetohydroxyacid synthase: a target for antimicrobial drug discovery.
    Pue N, Guddat LW.
    Curr Pharm Des; 2014; 20(5):740-53. PubMed ID: 23688082
    [Abstract] [Full Text] [Related]

  • 2. Bacterial acetohydroxyacid synthase and its inhibitors--a summary of their structure, biological activity and current status.
    Gedi V, Yoon MY.
    FEBS J; 2012 Mar; 279(6):946-63. PubMed ID: 22284339
    [Abstract] [Full Text] [Related]

  • 3. Structure and mechanism of inhibition of plant acetohydroxyacid synthase.
    Duggleby RG, McCourt JA, Guddat LW.
    Plant Physiol Biochem; 2008 Mar; 46(3):309-24. PubMed ID: 18234503
    [Abstract] [Full Text] [Related]

  • 4. Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides.
    Garcia MD, Wang JG, Lonhienne T, Guddat LW.
    FEBS J; 2017 Jul; 284(13):2037-2051. PubMed ID: 28485824
    [Abstract] [Full Text] [Related]

  • 5. Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections.
    Garcia MD, Chua SMH, Low YS, Lee YT, Agnew-Francis K, Wang JG, Nouwens A, Lonhienne T, Williams CM, Fraser JA, Guddat LW.
    Proc Natl Acad Sci U S A; 2018 Oct 09; 115(41):E9649-E9658. PubMed ID: 30249642
    [Abstract] [Full Text] [Related]

  • 6. Triazolopyrimidines as a New Herbicidal Lead for Combating Weed Resistance Associated with Acetohydroxyacid Synthase Mutation.
    Liu YC, Qu RY, Chen Q, Yang JF, Cong-Wei N, Zhen X, Yang GF.
    J Agric Food Chem; 2016 Jun 22; 64(24):4845-57. PubMed ID: 27265721
    [Abstract] [Full Text] [Related]

  • 7. Biosynthesis of 2-aceto-2-hydroxy acids: acetolactate synthases and acetohydroxyacid synthases.
    Chipman D, Barak Z, Schloss JV.
    Biochim Biophys Acta; 1998 Jun 29; 1385(2):401-19. PubMed ID: 9655946
    [Abstract] [Full Text] [Related]

  • 8. Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors.
    Pang SS, Duggleby RG, Guddat LW.
    J Mol Biol; 2002 Mar 22; 317(2):249-62. PubMed ID: 11902841
    [Abstract] [Full Text] [Related]

  • 9. Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.
    Wang JG, Lee PK, Dong YH, Pang SS, Duggleby RG, Li ZM, Guddat LW.
    FEBS J; 2009 Mar 22; 276(5):1282-90. PubMed ID: 19187232
    [Abstract] [Full Text] [Related]

  • 10. Structural insights into the mechanism of inhibition of AHAS by herbicides.
    Lonhienne T, Garcia MD, Pierens G, Mobli M, Nouwens A, Guddat LW.
    Proc Natl Acad Sci U S A; 2018 Feb 27; 115(9):E1945-E1954. PubMed ID: 29440497
    [Abstract] [Full Text] [Related]

  • 11. Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.
    Pham NC, Moon JY, Cho JH, Lee SJ, Park JS, Kim DE, Park Y, Yoon MY.
    Biosci Biotechnol Biochem; 2010 Feb 27; 74(11):2281-6. PubMed ID: 21071847
    [Abstract] [Full Text] [Related]

  • 12. Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads.
    Low YS, Garcia MD, Lonhienne T, Fraser JA, Schenk G, Guddat LW.
    Sci Rep; 2021 Oct 26; 11(1):21055. PubMed ID: 34702838
    [Abstract] [Full Text] [Related]

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  • 14. Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families.
    Garcia MD, Nouwens A, Lonhienne TG, Guddat LW.
    Proc Natl Acad Sci U S A; 2017 Feb 14; 114(7):E1091-E1100. PubMed ID: 28137884
    [Abstract] [Full Text] [Related]

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  • 16. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase.
    Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY.
    Biochimie; 2013 Jul 14; 95(7):1411-21. PubMed ID: 23523771
    [Abstract] [Full Text] [Related]

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  • 18. Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase.
    Lee YT, Cui CJ, Chow EW, Pue N, Lonhienne T, Wang JG, Fraser JA, Guddat LW.
    J Med Chem; 2013 Jan 10; 56(1):210-9. PubMed ID: 23237384
    [Abstract] [Full Text] [Related]

  • 19. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I.
    Belenky I, Steinmetz A, Vyazmensky M, Barak Z, Tittmann K, Chipman DM.
    FEBS J; 2012 Jun 10; 279(11):1967-79. PubMed ID: 22443469
    [Abstract] [Full Text] [Related]

  • 20. Identification and characterization of inhibitors of Haemophilus influenzae acetohydroxyacid synthase.
    Gedi V, Moon JY, Lim WM, Lee MY, Lee SC, Koo BS, Govindwar S, Yoon MY.
    Enzyme Microb Technol; 2011 Jun 10; 49(1):1-5. PubMed ID: 22112263
    [Abstract] [Full Text] [Related]


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