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248 related items for PubMed ID: 23688082
1. Acetohydroxyacid synthase: a target for antimicrobial drug discovery. Pue N, Guddat LW. Curr Pharm Des; 2014; 20(5):740-53. PubMed ID: 23688082 [Abstract] [Full Text] [Related]
2. Bacterial acetohydroxyacid synthase and its inhibitors--a summary of their structure, biological activity and current status. Gedi V, Yoon MY. FEBS J; 2012 Mar; 279(6):946-63. PubMed ID: 22284339 [Abstract] [Full Text] [Related]
3. Structure and mechanism of inhibition of plant acetohydroxyacid synthase. Duggleby RG, McCourt JA, Guddat LW. Plant Physiol Biochem; 2008 Mar; 46(3):309-24. PubMed ID: 18234503 [Abstract] [Full Text] [Related]
4. Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides. Garcia MD, Wang JG, Lonhienne T, Guddat LW. FEBS J; 2017 Jul; 284(13):2037-2051. PubMed ID: 28485824 [Abstract] [Full Text] [Related]
5. Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Garcia MD, Chua SMH, Low YS, Lee YT, Agnew-Francis K, Wang JG, Nouwens A, Lonhienne T, Williams CM, Fraser JA, Guddat LW. Proc Natl Acad Sci U S A; 2018 Oct 09; 115(41):E9649-E9658. PubMed ID: 30249642 [Abstract] [Full Text] [Related]
6. Triazolopyrimidines as a New Herbicidal Lead for Combating Weed Resistance Associated with Acetohydroxyacid Synthase Mutation. Liu YC, Qu RY, Chen Q, Yang JF, Cong-Wei N, Zhen X, Yang GF. J Agric Food Chem; 2016 Jun 22; 64(24):4845-57. PubMed ID: 27265721 [Abstract] [Full Text] [Related]
7. Biosynthesis of 2-aceto-2-hydroxy acids: acetolactate synthases and acetohydroxyacid synthases. Chipman D, Barak Z, Schloss JV. Biochim Biophys Acta; 1998 Jun 29; 1385(2):401-19. PubMed ID: 9655946 [Abstract] [Full Text] [Related]
8. Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors. Pang SS, Duggleby RG, Guddat LW. J Mol Biol; 2002 Mar 22; 317(2):249-62. PubMed ID: 11902841 [Abstract] [Full Text] [Related]
9. Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. Wang JG, Lee PK, Dong YH, Pang SS, Duggleby RG, Li ZM, Guddat LW. FEBS J; 2009 Mar 22; 276(5):1282-90. PubMed ID: 19187232 [Abstract] [Full Text] [Related]
10. Structural insights into the mechanism of inhibition of AHAS by herbicides. Lonhienne T, Garcia MD, Pierens G, Mobli M, Nouwens A, Guddat LW. Proc Natl Acad Sci U S A; 2018 Feb 27; 115(9):E1945-E1954. PubMed ID: 29440497 [Abstract] [Full Text] [Related]
11. Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors. Pham NC, Moon JY, Cho JH, Lee SJ, Park JS, Kim DE, Park Y, Yoon MY. Biosci Biotechnol Biochem; 2010 Feb 27; 74(11):2281-6. PubMed ID: 21071847 [Abstract] [Full Text] [Related]
12. Triazolopyrimidine herbicides are potent inhibitors of Aspergillus fumigatus acetohydroxyacid synthase and potential antifungal drug leads. Low YS, Garcia MD, Lonhienne T, Fraser JA, Schenk G, Guddat LW. Sci Rep; 2021 Oct 26; 11(1):21055. PubMed ID: 34702838 [Abstract] [Full Text] [Related]
16. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase. Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY. Biochimie; 2013 Jul 14; 95(7):1411-21. PubMed ID: 23523771 [Abstract] [Full Text] [Related]
18. Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. Lee YT, Cui CJ, Chow EW, Pue N, Lonhienne T, Wang JG, Fraser JA, Guddat LW. J Med Chem; 2013 Jan 10; 56(1):210-9. PubMed ID: 23237384 [Abstract] [Full Text] [Related]
19. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I. Belenky I, Steinmetz A, Vyazmensky M, Barak Z, Tittmann K, Chipman DM. FEBS J; 2012 Jun 10; 279(11):1967-79. PubMed ID: 22443469 [Abstract] [Full Text] [Related]
20. Identification and characterization of inhibitors of Haemophilus influenzae acetohydroxyacid synthase. Gedi V, Moon JY, Lim WM, Lee MY, Lee SC, Koo BS, Govindwar S, Yoon MY. Enzyme Microb Technol; 2011 Jun 10; 49(1):1-5. PubMed ID: 22112263 [Abstract] [Full Text] [Related] Page: [Next] [New Search]