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157 related items for PubMed ID: 23692140

  • 1. A mutational analysis of the active site loop residues in cis-3-Chloroacrylic acid dehalogenase.
    Schroeder GK, Huddleston JP, Johnson WH, Whitman CP.
    Biochemistry; 2013 Jun 18; 52(24):4204-16. PubMed ID: 23692140
    [Abstract] [Full Text] [Related]

  • 2. Inactivation of Cg10062, a cis-3-chloroacrylic acid dehalogenase homologue in Corynebacterium glutamicum, by (R)- and (S)-oxirane-2-carboxylate: analysis and implications.
    Robertson BA, Johnson WH, Lo HH, Whitman CP.
    Biochemistry; 2008 Aug 19; 47(33):8796-803. PubMed ID: 18646866
    [Abstract] [Full Text] [Related]

  • 3. Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily.
    Poelarends GJ, Serrano H, Person MD, Johnson WH, Whitman CP.
    Biochemistry; 2008 Aug 05; 47(31):8139-47. PubMed ID: 18598055
    [Abstract] [Full Text] [Related]

  • 4. Reactions of Cg10062, a cis-3-Chloroacrylic Acid Dehalogenase Homologue, with Acetylene and Allene Substrates: Evidence for a Hydration-Dependent Decarboxylation.
    Huddleston JP, Johnson WH, Schroeder GK, Whitman CP.
    Biochemistry; 2015 May 19; 54(19):3009-23. PubMed ID: 25894805
    [Abstract] [Full Text] [Related]

  • 5. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate.
    de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW.
    J Biol Chem; 2007 Jan 26; 282(4):2440-9. PubMed ID: 17121835
    [Abstract] [Full Text] [Related]

  • 6. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Implications for the catalytic and inactivation mechanisms.
    Guo Y, Serrano H, Johnson WH, Ernst S, Hackert ML, Whitman CP.
    Bioorg Chem; 2011 Feb 26; 39(1):1-9. PubMed ID: 21074239
    [Abstract] [Full Text] [Related]

  • 7. Characterization of a newly identified mycobacterial tautomerase with promiscuous dehalogenase and hydratase activities reveals a functional link to a recently diverged cis-3-chloroacrylic acid dehalogenase.
    Baas BJ, Zandvoort E, Wasiel AA, Quax WJ, Poelarends GJ.
    Biochemistry; 2011 Apr 12; 50(14):2889-99. PubMed ID: 21370851
    [Abstract] [Full Text] [Related]

  • 8. Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications.
    Poelarends GJ, Serrano H, Johnson WH, Whitman CP.
    Biochemistry; 2004 Jun 08; 43(22):7187-96. PubMed ID: 15170356
    [Abstract] [Full Text] [Related]

  • 9. Reaction of cis-3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine.
    Schroeder GK, Johnson WH, Huddleston JP, Serrano H, Johnson KA, Whitman CP.
    J Am Chem Soc; 2012 Jan 11; 134(1):293-304. PubMed ID: 22129074
    [Abstract] [Full Text] [Related]

  • 10. The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis.
    Azurmendi HF, Wang SC, Massiah MA, Poelarends GJ, Whitman CP, Mildvan AS.
    Biochemistry; 2004 Apr 13; 43(14):4082-91. PubMed ID: 15065850
    [Abstract] [Full Text] [Related]

  • 11. Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases.
    Poelarends GJ, Serrano H, Person MD, Johnson WH, Murzin AG, Whitman CP.
    Biochemistry; 2004 Jan 27; 43(3):759-72. PubMed ID: 14730981
    [Abstract] [Full Text] [Related]

  • 12. Pre-steady-state kinetic analysis of cis-3-chloroacrylic acid dehalogenase: analysis and implications.
    Robertson BA, Schroeder GK, Jin Z, Johnson KA, Whitman CP.
    Biochemistry; 2009 Dec 15; 48(49):11737-44. PubMed ID: 19856961
    [Abstract] [Full Text] [Related]

  • 13. Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?
    Poelarends GJ, Johnson WH, Serrano H, Whitman CP.
    Biochemistry; 2007 Aug 21; 46(33):9596-604. PubMed ID: 17661448
    [Abstract] [Full Text] [Related]

  • 14. Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily.
    LeVieux JA, Baas BJ, Kaoud TS, Davidson R, Babbitt PC, Zhang YJ, Whitman CP.
    Arch Biochem Biophys; 2017 Dec 15; 636():50-56. PubMed ID: 29111295
    [Abstract] [Full Text] [Related]

  • 15. trans-3-Chloroacrylic acid dehalogenase from Pseudomonas pavonaceae 170 shares structural and mechanistic similarities with 4-oxalocrotonate tautomerase.
    Poelarends GJ, Saunier R, Janssen DB.
    J Bacteriol; 2001 Jul 15; 183(14):4269-77. PubMed ID: 11418568
    [Abstract] [Full Text] [Related]

  • 16. Cg10062 Catalysis Forges a Link between Acetylenecarboxylic Acid and Bacterial Metabolism.
    Mathes Hewage A, Nayebi Gavgani H, Chi D, Qiu B, Geiger JH, Draths K.
    Biochemistry; 2021 Dec 28; 60(51):3879-3886. PubMed ID: 34910871
    [Abstract] [Full Text] [Related]

  • 17. A pre-steady state kinetic analysis of the αY60W mutant of trans-3-chloroacrylic acid dehalogenase: implications for the mechanism of the wild-type enzyme.
    Huddleston JP, Schroeder GK, Johnson KA, Whitman CP.
    Biochemistry; 2012 Nov 20; 51(46):9420-35. PubMed ID: 23110338
    [Abstract] [Full Text] [Related]

  • 18. Resolution of the uncertainty in the kinetic mechanism for the trans-3-Chloroacrylic acid dehalogenase-catalyzed reaction.
    Huddleston JP, Wang SC, Johnson KA, Whitman CP.
    Arch Biochem Biophys; 2017 Jun 01; 623-624():9-19. PubMed ID: 28499743
    [Abstract] [Full Text] [Related]

  • 19. The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily.
    de Jong RM, Brugman W, Poelarends GJ, Whitman CP, Dijkstra BW.
    J Biol Chem; 2004 Mar 19; 279(12):11546-52. PubMed ID: 14701869
    [Abstract] [Full Text] [Related]

  • 20. Reaction mechanism of cis-3-chloroacrylic acid dehalogenase: a theoretical study.
    Sevastik R, Whitman CP, Himo F.
    Biochemistry; 2009 Oct 13; 48(40):9641-9. PubMed ID: 19725565
    [Abstract] [Full Text] [Related]

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