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Journal Abstract Search
217 related items for PubMed ID: 23697606
1. The potential for drug supersaturation during intestinal processing of lipid-based formulations may be enhanced for basic drugs. Yeap YY, Trevaskis NL, Porter CJ. Mol Pharm; 2013 Jul 01; 10(7):2601-15. PubMed ID: 23697606 [Abstract] [Full Text] [Related]
2. Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation. Yeap YY, Trevaskis NL, Quach T, Tso P, Charman WN, Porter CJ. Mol Pharm; 2013 May 06; 10(5):1874-89. PubMed ID: 23480483 [Abstract] [Full Text] [Related]
4. Polymeric Precipitation Inhibitors Promote Fenofibrate Supersaturation and Enhance Drug Absorption from a Type IV Lipid-Based Formulation. Suys EJA, Chalmers DK, Pouton CW, Porter CJH. Mol Pharm; 2018 Jun 04; 15(6):2355-2371. PubMed ID: 29659287 [Abstract] [Full Text] [Related]
5. Transformation of poorly water-soluble drugs into lipophilic ionic liquids enhances oral drug exposure from lipid based formulations. Sahbaz Y, Williams HD, Nguyen TH, Saunders J, Ford L, Charman SA, Scammells PJ, Porter CJ. Mol Pharm; 2015 Jun 01; 12(6):1980-91. PubMed ID: 25905624 [Abstract] [Full Text] [Related]
6. In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine. Devraj R, Williams HD, Warren DB, Mohsin K, Porter CJ, Pouton CW. Eur J Pharm Sci; 2013 Jul 16; 49(4):748-60. PubMed ID: 23684915 [Abstract] [Full Text] [Related]
7. Toward the establishment of standardized in vitro tests for lipid-based formulations. 2. The effect of bile salt concentration and drug loading on the performance of type I, II, IIIA, IIIB, and IV formulations during in vitro digestion. Williams HD, Anby MU, Sassene P, Kleberg K, Bakala-N'Goma JC, Calderone M, Jannin V, Igonin A, Partheil A, Marchaud D, Jule E, Vertommen J, Maio M, Blundell R, Benameur H, Carrière F, Müllertz A, Pouton CW, Porter CJ. Mol Pharm; 2012 Nov 05; 9(11):3286-300. PubMed ID: 23030411 [Abstract] [Full Text] [Related]
8. Lipid absorption triggers drug supersaturation at the intestinal unstirred water layer and promotes drug absorption from mixed micelles. Yeap YY, Trevaskis NL, Porter CJ. Pharm Res; 2013 Dec 05; 30(12):3045-58. PubMed ID: 23793990 [Abstract] [Full Text] [Related]
9. Separation and characterization of the colloidal phases produced on digestion of common formulation lipids and assessment of their impact on the apparent solubility of selected poorly water-soluble drugs. Kossena GA, Boyd BJ, Porter CJ, Charman WN. J Pharm Sci; 2003 Mar 05; 92(3):634-48. PubMed ID: 12587125 [Abstract] [Full Text] [Related]
11. In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products. Devraj R, Williams HD, Warren DB, Mullertz A, Porter CJ, Pouton CW. Int J Pharm; 2013 Jan 30; 441(1-2):323-33. PubMed ID: 23178598 [Abstract] [Full Text] [Related]
12. Lipid digestion as a trigger for supersaturation: evaluation of the impact of supersaturation stabilization on the in vitro and in vivo performance of self-emulsifying drug delivery systems. Anby MU, Williams HD, McIntosh M, Benameur H, Edwards GA, Pouton CW, Porter CJ. Mol Pharm; 2012 Jul 02; 9(7):2063-79. PubMed ID: 22656917 [Abstract] [Full Text] [Related]
15. An in vitro digestion test that reflects rat intestinal conditions to probe the importance of formulation digestion vs first pass metabolism in Danazol bioavailability from lipid based formulations. Anby MU, Nguyen TH, Yeap YY, Feeney OM, Williams HD, Benameur H, Pouton CW, Porter CJ. Mol Pharm; 2014 Nov 03; 11(11):4069-83. PubMed ID: 25265395 [Abstract] [Full Text] [Related]
18. Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug. Larsen AT, Holm R, Müllertz A. Eur J Pharm Biopharm; 2017 Aug 03; 117():308-314. PubMed ID: 28465239 [Abstract] [Full Text] [Related]