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Journal Abstract Search

591 related items for PubMed ID: 23707573

  • 1. Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: molecular modeling with biological evaluation.
    Xu X, Lu Y, Chen L, Chen J, Luo X, Shen X.
    Steroids; 2013 Sep; 78(9):813-22. PubMed ID: 23707573
    [Abstract] [Full Text] [Related]

  • 2. Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor.
    Xu X, Xu X, Liu P, Zhu ZY, Chen J, Fu HA, Chen LL, Hu LH, Shen X.
    J Biol Chem; 2015 Aug 07; 290(32):19888-99. PubMed ID: 26100621
    [Abstract] [Full Text] [Related]

  • 3. Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.
    Owsley E, Chiang JY.
    Biochem Biophys Res Commun; 2003 Apr 25; 304(1):191-5. PubMed ID: 12705905
    [Abstract] [Full Text] [Related]

  • 4. The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma.
    Giri S, Rattan R, Singh AK, Singh I.
    J Immunol; 2004 Oct 15; 173(8):5196-208. PubMed ID: 15470065
    [Abstract] [Full Text] [Related]

  • 5. Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
    Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Patel NS, Di Paola R, Genovese T, Chatterjee PK, Di Rosa M, Caputi AP, Thiemermann C.
    Br J Pharmacol; 2003 Sep 15; 140(2):366-76. PubMed ID: 12970094
    [Abstract] [Full Text] [Related]

  • 6. The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate.
    Cui J, Heard TS, Yu J, Lo JL, Huang L, Li Y, Schaeffer JM, Wright SD.
    J Biol Chem; 2002 Jul 19; 277(29):25963-9. PubMed ID: 12004058
    [Abstract] [Full Text] [Related]

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  • 8. 15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells.
    Chen ZY, Tseng CC.
    Mol Pharmacol; 2005 Nov 19; 68(5):1203-13. PubMed ID: 16077033
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  • 10. Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.
    Hoeke MO, Plass JR, Heegsma J, Geuken M, van Rijsbergen D, Baller JF, Kuipers F, Moshage H, Jansen PL, Faber KN.
    Hepatology; 2009 Jan 19; 49(1):151-9. PubMed ID: 19111018
    [Abstract] [Full Text] [Related]

  • 11. 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) signals through retinoic acid receptor-related orphan receptor-alpha but not peroxisome proliferator-activated receptor-gamma in human vascular endothelial cells: the effect of 15d-PGJ2 on tumor necrosis factor-alpha-induced gene expression.
    Migita H, Morser J.
    Arterioscler Thromb Vasc Biol; 2005 Apr 19; 25(4):710-6. PubMed ID: 15662020
    [Abstract] [Full Text] [Related]

  • 12. Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.
    Deng R, Yang D, Yang J, Yan B.
    J Pharmacol Exp Ther; 2006 Apr 19; 317(1):317-25. PubMed ID: 16371446
    [Abstract] [Full Text] [Related]

  • 13. 15-Deoxy-Delta12,14-prostaglandin J2 inhibits IL-1beta-induced cyclooxygenase-2 expression in mesangial cells.
    Sawano H, Haneda M, Sugimoto T, Inoki K, Koya D, Kikkawa R.
    Kidney Int; 2002 Jun 19; 61(6):1957-67. PubMed ID: 12028436
    [Abstract] [Full Text] [Related]

  • 14. 15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma.
    Okano H, Shiraki K, Inoue H, Yamanaka Y, Kawakita T, Saitou Y, Yamaguchi Y, Enokimura N, Yamamoto N, Sugimoto K, Murata K, Nakano T.
    Lab Invest; 2003 Oct 19; 83(10):1529-39. PubMed ID: 14563954
    [Abstract] [Full Text] [Related]

  • 15. Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
    Pineda Torra I, Claudel T, Duval C, Kosykh V, Fruchart JC, Staels B.
    Mol Endocrinol; 2003 Feb 19; 17(2):259-72. PubMed ID: 12554753
    [Abstract] [Full Text] [Related]

  • 16. Bile acid nuclear receptor FXR and digestive system diseases.
    Ding L, Yang L, Wang Z, Huang W.
    Acta Pharm Sin B; 2015 Mar 19; 5(2):135-44. PubMed ID: 26579439
    [Abstract] [Full Text] [Related]

  • 17. SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes.
    Balasubramaniyan N, Luo Y, Sun AQ, Suchy FJ.
    J Biol Chem; 2013 May 10; 288(19):13850-62. PubMed ID: 23546875
    [Abstract] [Full Text] [Related]

  • 18. Peroxisome proliferator-activated receptor gamma is required for the inhibitory effect of ciglitazone but not 15-deoxy-Delta 12,14-prostaglandin J2 on the NFkappaB pathway in human endothelial cells.
    Kaplan J, Cook JA, O'Connor M, Zingarelli B.
    Shock; 2007 Dec 10; 28(6):722-726. PubMed ID: 17621259
    [Abstract] [Full Text] [Related]

  • 19. Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARgamma ligand-binding domain by multi-wavelength global fitting.
    Shiraki T, Kodama TS, Shiki S, Nakagawa T, Jingami H.
    Biochem J; 2006 Feb 01; 393(Pt 3):749-55. PubMed ID: 16236024
    [Abstract] [Full Text] [Related]

  • 20. Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages.
    Piraino G, Cook JA, O'Connor M, Hake PW, Burroughs TJ, Teti D, Zingarelli B.
    Shock; 2006 Aug 01; 26(2):146-53. PubMed ID: 16878022
    [Abstract] [Full Text] [Related]

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