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401 related items for PubMed ID: 23708869

  • 1. Induction of apoptosis and antitumor effects of a small molecule inhibitor of Bcl-2 and Bcl-xl, gossypol acetate, in multiple myeloma in vitro and in vivo.
    Lin J, Wu Y, Yang D, Zhao Y.
    Oncol Rep; 2013 Aug; 30(2):731-8. PubMed ID: 23708869
    [Abstract] [Full Text] [Related]

  • 2. [Effect of apogossypolone on induction apoptosis in multiple myeloma cells and its mechanisms].
    Lin J, Wu YJ, Yang DJ, Zhao YQ.
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2009 Feb; 17(1):92-8. PubMed ID: 19236755
    [Abstract] [Full Text] [Related]

  • 3. ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells.
    Sun J, Li ZM, Hu ZY, Lin XB, Zhou NN, Xian LJ, Yang DJ, Jiang WQ.
    Anticancer Drugs; 2008 Nov; 19(10):967-74. PubMed ID: 18827561
    [Abstract] [Full Text] [Related]

  • 4. ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells.
    Xin J, Zhan YH, Xia LM, Zhu HW, Nie YZ, Liang JM, Tian J.
    Biomed Pharmacother; 2013 Feb; 67(1):88-95. PubMed ID: 23201009
    [Abstract] [Full Text] [Related]

  • 5. [Effect of gossypol acetate on proliferation and apoptosis in Raji lymphoblastoid cell line].
    Cheng W, Li YM, Yang DJ, Zhao YQ.
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2009 Oct; 31(5):527-32. PubMed ID: 19968063
    [Abstract] [Full Text] [Related]

  • 6. Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.
    Sun Y, Wu J, Aboukameel A, Banerjee S, Arnold AA, Chen J, Nikolovska-Coleska Z, Lin Y, Ling X, Yang D, Wang S, Al-Katib A, Mohammad RM.
    Cancer Biol Ther; 2008 Sep; 7(9):1418-26. PubMed ID: 18769131
    [Abstract] [Full Text] [Related]

  • 7. Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2.
    Lei X, Chen Y, Du G, Yu W, Wang X, Qu H, Xia B, He H, Mao J, Zong W, Liao X, Mehrpour M, Hao X, Chen Q.
    FASEB J; 2006 Oct; 20(12):2147-9. PubMed ID: 16935937
    [Abstract] [Full Text] [Related]

  • 8. [Effects of CPUY013, a novel Topo I inhibitor, on human gastric adenocarcinoma BGC823 cells in vitro and in vivo].
    Ji YB, Zhou JH, Zuo MX, You QD.
    Yao Xue Xue Bao; 2008 Aug; 43(8):811-8. PubMed ID: 18956773
    [Abstract] [Full Text] [Related]

  • 9. Nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL, (-)-Gossypol, enhances biological effect of genistein against BxPC-3 human pancreatic cancer cell line.
    Mohammad RM, Wang S, Banerjee S, Wu X, Chen J, Sarkar FH.
    Pancreas; 2005 Nov; 31(4):317-24. PubMed ID: 16258364
    [Abstract] [Full Text] [Related]

  • 10. Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma.
    Mi JX, Wang GF, Wang HB, Sun XQ, Ni XY, Zhang XW, Tang JM, Yang DJ.
    Acta Pharmacol Sin; 2008 Dec; 29(12):1467-77. PubMed ID: 19026166
    [Abstract] [Full Text] [Related]

  • 11. Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa.
    Meng Y, Tang W, Dai Y, Wu X, Liu M, Ji Q, Ji M, Pienta K, Lawrence T, Xu L.
    Mol Cancer Ther; 2008 Jul; 7(7):2192-202. PubMed ID: 18645028
    [Abstract] [Full Text] [Related]

  • 12. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
    Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.
    Hepatology; 2010 Oct; 52(4):1310-21. PubMed ID: 20799354
    [Abstract] [Full Text] [Related]

  • 13. Aspirin inhibits proliferation and induces apoptosis of multiple myeloma cells through regulation of Bcl-2 and Bax and suppression of VEGF.
    Ding JH, Yuan LY, Huang RB, Chen GA.
    Eur J Haematol; 2014 Oct; 93(4):329-39. PubMed ID: 24766194
    [Abstract] [Full Text] [Related]

  • 14. [Apoptosis of multiple myeloma cells induced by gossypol acetic acid in vitro and its mechanism].
    Wang WQ, Li R, Bai QX, Zhang WP, Wang JH, Wang Z, Chen XQ, Huang GS.
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2009 Dec; 17(6):1459-63. PubMed ID: 20030926
    [Abstract] [Full Text] [Related]

  • 15. Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis.
    Zhao J, Chen X, Lin W, Wu G, Zhuang Q, Zhong X, Hong Z, Peng J.
    Int J Oncol; 2013 Mar; 42(3):971-8. PubMed ID: 23338043
    [Abstract] [Full Text] [Related]

  • 16. AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model.
    McGregor N, Patel L, Craig M, Weidner S, Wang S, Pienta KJ.
    J Cell Biochem; 2010 Aug 01; 110(5):1187-94. PubMed ID: 20589722
    [Abstract] [Full Text] [Related]

  • 17. Resveratrol as a novel agent for treatment of multiple myeloma with matrix metalloproteinase inhibitory activity.
    Sun CY, Hu Y, Guo T, Wang HF, Zhang XP, He WJ, Tan H.
    Acta Pharmacol Sin; 2006 Nov 01; 27(11):1447-52. PubMed ID: 17049120
    [Abstract] [Full Text] [Related]

  • 18. A novel NF-kappaB inhibitor DHMEQ selectively targets constitutive NF-kappaB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo.
    Watanabe M, Dewan MZ, Okamura T, Sasaki M, Itoh K, Higashihara M, Mizoguchi H, Honda M, Sata T, Watanabe T, Yamamoto N, Umezawa K, Horie R.
    Int J Cancer; 2005 Mar 10; 114(1):32-8. PubMed ID: 15523684
    [Abstract] [Full Text] [Related]

  • 19. Molecular mechanisms of (-)-gossypol-induced apoptosis in human prostate cancer cells.
    Huang YW, Wang LS, Chang HL, Ye W, Dowd MK, Wan PJ, Lin YC.
    Anticancer Res; 2006 Mar 10; 26(3A):1925-33. PubMed ID: 16827126
    [Abstract] [Full Text] [Related]

  • 20. [Homoharringtonine combined arsenic trioxide induced apoptosis in human multiple myeloma cell line RPMI 8226: an experimental research].
    Zhou XJ, Zhou YH, Chen XH, Qian WB.
    Zhongguo Zhong Xi Yi Jie He Za Zhi; 2013 Jun 10; 33(6):834-9. PubMed ID: 23980369
    [Abstract] [Full Text] [Related]

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