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221 related items for PubMed ID: 23709189

  • 1. Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells.
    Goldberg AA, Titorenko VI, Beach A, Abdelbaqi K, Safe S, Sanderson JT.
    Invest New Drugs; 2014 Feb; 32(1):25-36. PubMed ID: 23709189
    [Abstract] [Full Text] [Related]

  • 2. Antiandrogenic and growth inhibitory effects of ring-substituted analogs of 3,3'-diindolylmethane (ring-DIMs) in hormone-responsive LNCaP human prostate cancer cells.
    Abdelbaqi K, Lack N, Guns ET, Kotha L, Safe S, Sanderson JT.
    Prostate; 2011 Sep 15; 71(13):1401-12. PubMed ID: 21321979
    [Abstract] [Full Text] [Related]

  • 3. Diindolylmethane and its halogenated derivatives induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK).
    Draz H, Goldberg AA, Titorenko VI, Tomlinson Guns ES, Safe SH, Sanderson JT.
    Cell Signal; 2017 Dec 15; 40():172-182. PubMed ID: 28923415
    [Abstract] [Full Text] [Related]

  • 4. 3,3'-Diindolylmethane (DIM) and its ring-substituted halogenated analogs (ring-DIMs) induce differential mechanisms of survival and death in androgen-dependent and -independent prostate cancer cells.
    Goldberg AA, Draz H, Montes-Grajales D, Olivero-Verbél J, Safe SH, Sanderson JT.
    Genes Cancer; 2015 May 15; 6(5-6):265-280. PubMed ID: 26124925
    [Abstract] [Full Text] [Related]

  • 5. Autophagy inhibition improves the chemotherapeutic efficacy of cruciferous vegetable-derived diindolymethane in a murine prostate cancer xenograft model.
    Draz H, Goldberg AA, Tomlinson Guns ES, Fazli L, Safe S, Sanderson JT.
    Invest New Drugs; 2018 Aug 15; 36(4):718-725. PubMed ID: 29607466
    [Abstract] [Full Text] [Related]

  • 6. 6-(3,4-Dihydro-1H-isoquinoline-2-yl)-N-(6-methoxypyridine-2-yl) nicotinamide-26 (DIMN-26) decreases cell proliferation by induction of apoptosis and downregulation of androgen receptor signaling in human prostate cancer cells.
    Choi HE, Shin JS, Leem DG, Kim SD, Cho WJ, Lee KT.
    Chem Biol Interact; 2016 Dec 25; 260():196-207. PubMed ID: 27720946
    [Abstract] [Full Text] [Related]

  • 7. 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor gamma-independent pathways.
    Chintharlapalli S, Papineni S, Safe S.
    Mol Pharmacol; 2007 Feb 25; 71(2):558-69. PubMed ID: 17093136
    [Abstract] [Full Text] [Related]

  • 8. Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells.
    Bhuiyan MM, Li Y, Banerjee S, Ahmed F, Wang Z, Ali S, Sarkar FH.
    Cancer Res; 2006 Oct 15; 66(20):10064-72. PubMed ID: 17047070
    [Abstract] [Full Text] [Related]

  • 9. Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells.
    Le HT, Schaldach CM, Firestone GL, Bjeldanes LF.
    J Biol Chem; 2003 Jun 06; 278(23):21136-45. PubMed ID: 12665522
    [Abstract] [Full Text] [Related]

  • 10. Chemopreventive effects of synthetic C-substituted diindolylmethanes originating from cruciferous vegetables in human oral cancer cells.
    Shin JA, Shim JH, Choi ES, Leem DH, Kwon KH, Lee SO, Safe S, Cho NP, Cho SD.
    Eur J Cancer Prev; 2011 Sep 06; 20(5):417-25. PubMed ID: 21597379
    [Abstract] [Full Text] [Related]

  • 11. Indole-3-carbinol and 3',3'-diindolylmethane modulate androgen's effect on C-C chemokine ligand 2 and monocyte attraction to prostate cancer cells.
    Kim EK, Kim YS, Milner JA, Wang TT.
    Cancer Prev Res (Phila); 2013 Jun 06; 6(6):519-29. PubMed ID: 23585426
    [Abstract] [Full Text] [Related]

  • 12. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
    Vanderlaag K, Su Y, Frankel AE, Burghardt RC, Barhoumi R, Chadalapaka G, Jutooru I, Safe S.
    BMC Cancer; 2010 Dec 03; 10():669. PubMed ID: 21129193
    [Abstract] [Full Text] [Related]

  • 13. 3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.
    Abdelrahim M, Newman K, Vanderlaag K, Samudio I, Safe S.
    Carcinogenesis; 2006 Apr 03; 27(4):717-28. PubMed ID: 16332727
    [Abstract] [Full Text] [Related]

  • 14. Cell cycle-dependent effects of 3,3'-diindolylmethane on proliferation and apoptosis of prostate cancer cells.
    Chinnakannu K, Chen D, Li Y, Wang Z, Dou QP, Reddy GP, Sarkar FH.
    J Cell Physiol; 2009 Apr 03; 219(1):94-9. PubMed ID: 19062173
    [Abstract] [Full Text] [Related]

  • 15. Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the mitochondrial pathway.
    Nachshon-Kedmi M, Yannai S, Fares FA.
    Br J Cancer; 2004 Oct 04; 91(7):1358-63. PubMed ID: 15328526
    [Abstract] [Full Text] [Related]

  • 16. 3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model.
    Cho HJ, Park SY, Kim EJ, Kim JK, Park JH.
    Mol Carcinog; 2011 Feb 04; 50(2):100-12. PubMed ID: 21229607
    [Abstract] [Full Text] [Related]

  • 17. Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells.
    Sun SY, Yue P, Lotan R.
    Oncogene; 2000 Sep 14; 19(39):4513-22. PubMed ID: 11002424
    [Abstract] [Full Text] [Related]

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