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Journal Abstract Search
377 related items for PubMed ID: 23732298
1. Dual roles of nuclear receptor liver X receptor α (LXRα) in the CYP3A4 expression in human hepatocytes as a positive and negative regulator. Watanabe K, Sakurai K, Tsuchiya Y, Yamazoe Y, Yoshinari K. Biochem Pharmacol; 2013 Aug 01; 86(3):428-36. PubMed ID: 23732298 [Abstract] [Full Text] [Related]
2. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways. Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P. Drug Metab Dispos; 2007 Jul 01; 35(7):1032-41. PubMed ID: 17392393 [Abstract] [Full Text] [Related]
3. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes. Sahi J, Shord SS, Lindley C, Ferguson S, LeCluyse EL. J Biochem Mol Toxicol; 2009 Jul 01; 23(1):43-58. PubMed ID: 19202563 [Abstract] [Full Text] [Related]
4. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity. Chang HY, Chen CJ, Ma WC, Cheng WK, Lin YN, Lee YR, Chen JJ, Lim YP. Phytomedicine; 2017 Dec 01; 36():37-49. PubMed ID: 29157826 [Abstract] [Full Text] [Related]
5. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression. Li T, Chiang JY. Drug Metab Dispos; 2006 May 01; 34(5):756-64. PubMed ID: 16455805 [Abstract] [Full Text] [Related]
8. Unveiling a new essential cis element for the transactivation of the CYP3A4 gene by xenobiotics. Toriyabe T, Nagata K, Takada T, Aratsu Y, Matsubara T, Yoshinari K, Yamazoe Y. Mol Pharmacol; 2009 Mar 01; 75(3):677-84. PubMed ID: 19074998 [Abstract] [Full Text] [Related]
9. Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene. Krausova L, Stejskalova L, Wang H, Vrzal R, Dvorak Z, Mani S, Pavek P. Biochem Pharmacol; 2011 Dec 01; 82(11):1771-80. PubMed ID: 21920351 [Abstract] [Full Text] [Related]
12. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha. Ferguson SS, Chen Y, LeCluyse EL, Negishi M, Goldstein JA. Mol Pharmacol; 2005 Sep 01; 68(3):747-57. PubMed ID: 15933212 [Abstract] [Full Text] [Related]
13. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor. Faucette SR, Sueyoshi T, Smith CM, Negishi M, Lecluyse EL, Wang H. J Pharmacol Exp Ther; 2006 Jun 01; 317(3):1200-9. PubMed ID: 16513849 [Abstract] [Full Text] [Related]
14. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR. Kanno Y, Tanuma N, Yazawa S, Zhao S, Inaba M, Nakamura S, Nemoto K, Inouye Y. Drug Metab Dispos; 2016 Aug 01; 44(8):1158-63. PubMed ID: 27197997 [Abstract] [Full Text] [Related]
15. Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG. Rasmussen MK, Daujat-Chavanieu M, Gerbal-Chaloin S. Toxicol Lett; 2017 Aug 05; 277():1-8. PubMed ID: 28571685 [Abstract] [Full Text] [Related]
18. Induction of human CYP2A6 is mediated by the pregnane X receptor with peroxisome proliferator-activated receptor-gamma coactivator 1alpha. Itoh M, Nakajima M, Higashi E, Yoshida R, Nagata K, Yamazoe Y, Yokoi T. J Pharmacol Exp Ther; 2006 Nov 05; 319(2):693-702. PubMed ID: 16857725 [Abstract] [Full Text] [Related]