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Journal Abstract Search

195 related items for PubMed ID: 23732987

  • 1. Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis.
    Nanou A, Higginbottom A, Valori CF, Wyles M, Ning K, Shaw P, Azzouz M.
    Mol Ther; 2013 Aug; 21(8):1486-96. PubMed ID: 23732987
    [Abstract] [Full Text] [Related]

  • 2. Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.
    Wang LJ, Lu YY, Muramatsu S, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Matsushita T, Hanazono Y, Kume A, Nagatsu T, Ozawa K, Nakano I.
    J Neurosci; 2002 Aug 15; 22(16):6920-8. PubMed ID: 12177190
    [Abstract] [Full Text] [Related]

  • 3. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.
    Azzouz M, Ralph GS, Storkebaum E, Walmsley LE, Mitrophanous KA, Kingsman SM, Carmeliet P, Mazarakis ND.
    Nature; 2004 May 27; 429(6990):413-7. PubMed ID: 15164063
    [Abstract] [Full Text] [Related]

  • 4. Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.
    Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ, Bendotti C.
    Brain; 2013 Nov 27; 136(Pt 11):3305-32. PubMed ID: 24065725
    [Abstract] [Full Text] [Related]

  • 5. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS.
    Foust KD, Salazar DL, Likhite S, Ferraiuolo L, Ditsworth D, Ilieva H, Meyer K, Schmelzer L, Braun L, Cleveland DW, Kaspar BK.
    Mol Ther; 2013 Dec 27; 21(12):2148-59. PubMed ID: 24008656
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  • 8. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Milanese M, Giribaldi F, Melone M, Bonifacino T, Musante I, Carminati E, Rossi PI, Vergani L, Voci A, Conti F, Puliti A, Bonanno G.
    Neurobiol Dis; 2014 Apr 27; 64():48-59. PubMed ID: 24361555
    [Abstract] [Full Text] [Related]

  • 9. GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.
    Li K, Hala TJ, Seetharam S, Poulsen DJ, Wright MC, Lepore AC.
    Neurobiol Dis; 2015 Jun 27; 78():12-23. PubMed ID: 25818008
    [Abstract] [Full Text] [Related]

  • 10. Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation.
    Diaz-Amarilla P, Miquel E, Trostchansky A, Trias E, Ferreira AM, Freeman BA, Cassina P, Barbeito L, Vargas MR, Rubbo H.
    Free Radic Biol Med; 2016 Jun 27; 95():112-20. PubMed ID: 27012417
    [Abstract] [Full Text] [Related]

  • 11. Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis.
    Neymotin A, Calingasan NY, Wille E, Naseri N, Petri S, Damiano M, Liby KT, Risingsong R, Sporn M, Beal MF, Kiaei M.
    Free Radic Biol Med; 2011 Jul 01; 51(1):88-96. PubMed ID: 21457778
    [Abstract] [Full Text] [Related]

  • 12. A New AAV10-U7-Mediated Gene Therapy Prolongs Survival and Restores Function in an ALS Mouse Model.
    Biferi MG, Cohen-Tannoudji M, Cappelletto A, Giroux B, Roda M, Astord S, Marais T, Bos C, Voit T, Ferry A, Barkats M.
    Mol Ther; 2017 Sep 06; 25(9):2038-2052. PubMed ID: 28663100
    [Abstract] [Full Text] [Related]

  • 13. Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice.
    Towne C, Setola V, Schneider BL, Aebischer P.
    Mol Ther; 2011 Feb 06; 19(2):274-83. PubMed ID: 21102563
    [Abstract] [Full Text] [Related]

  • 14. Urate mitigates oxidative stress and motor neuron toxicity of astrocytes derived from ALS-linked SOD1G93A mutant mice.
    Bakshi R, Xu Y, Mueller KA, Chen X, Granucci E, Paganoni S, Sadri-Vakili G, Schwarzschild MA.
    Mol Cell Neurosci; 2018 Oct 06; 92():12-16. PubMed ID: 29928993
    [Abstract] [Full Text] [Related]

  • 15. Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.
    Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, Barber SC, Loynes CA, Wood-Allum CA, Lunec J, Shaw PJ.
    Brain; 2005 Jul 06; 128(Pt 7):1686-706. PubMed ID: 15872021
    [Abstract] [Full Text] [Related]

  • 16. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.
    Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, Guo Y, Brown RH, Gao G, Xu Z.
    Hum Mol Genet; 2014 Feb 01; 23(3):668-81. PubMed ID: 24108104
    [Abstract] [Full Text] [Related]

  • 17. Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1.
    Tokuda E, Okawa E, Watanabe S, Ono S.
    Hum Mol Genet; 2014 Mar 01; 23(5):1271-85. PubMed ID: 24163136
    [Abstract] [Full Text] [Related]

  • 18. Novel behavioural characteristics of the superoxide dismutase 1 G93A (SOD1G93A ) mouse model of amyotrophic lateral sclerosis include sex-dependent phenotypes.
    Kreilaus F, Guerra S, Masanetz R, Menne V, Yerbury J, Karl T.
    Genes Brain Behav; 2020 Feb 01; 19(2):e12604. PubMed ID: 31412164
    [Abstract] [Full Text] [Related]

  • 19. Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice.
    Turner BJ, Ackerley S, Davies KE, Talbot K.
    Hum Mol Genet; 2010 Mar 01; 19(5):815-24. PubMed ID: 20008901
    [Abstract] [Full Text] [Related]

  • 20. Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models.
    Vargas MR, Burton NC, Kutzke J, Gan L, Johnson DA, Schäfer M, Werner S, Johnson JA.
    PLoS One; 2013 Mar 01; 8(2):e56625. PubMed ID: 23418589
    [Abstract] [Full Text] [Related]

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