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Journal Abstract Search

255 related items for PubMed ID: 2374143

  • 1. Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes.
    Farrell N, Qu Y, Hacker MP.
    J Med Chem; 1990 Aug; 33(8):2179-84. PubMed ID: 2374143
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, structural characterization, and antitumor properties of a novel class of large-ring platinum(II) chelate complexes incorporating the cis-1,4-diaminocyclohexane ligand in a unique locked boat conformation.
    Hoeschele JD, Showalter HD, Kraker AJ, Elliott WL, Roberts BJ, Kampf JW.
    J Med Chem; 1994 Aug 19; 37(17):2630-6. PubMed ID: 8064793
    [Abstract] [Full Text] [Related]

  • 3. Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups.
    Kraker AJ, Hoeschele JD, Elliott WL, Showalter HD, Sercel AD, Farrell NP.
    J Med Chem; 1992 Nov 27; 35(24):4526-32. PubMed ID: 1335074
    [Abstract] [Full Text] [Related]

  • 4. Chemical and biological studies on a series of novel (trans-(1R,2R)-, trans-(1S,2S)-, and cis-1,2-diaminocyclohexane)platinum(IV) carboxylate complexes.
    Khokhar AR, al-Baker S, Shamsuddin S, Siddik ZH.
    J Med Chem; 1997 Jan 03; 40(1):112-6. PubMed ID: 9016335
    [Abstract] [Full Text] [Related]

  • 5. Cytotoxicity of platinum(IV) and platinum(II) complexes containing 1R,2R-cyclohexanediamine as a ligand.
    Yamashita T, Hirose J, Noji M, Saito R, Tomida H, Kidani Y.
    Biol Pharm Bull; 1993 Oct 03; 16(10):1014-8. PubMed ID: 8287030
    [Abstract] [Full Text] [Related]

  • 6. Modulation of cytotoxicity and cellular pharmacology of 1,2-diaminocyclohexane platinum (IV) complexes mediated by axial and equatorial ligands.
    Kido Y, Khokhar AR, al-Baker S, Siddik ZH.
    Cancer Res; 1993 Oct 01; 53(19):4567-72. PubMed ID: 8402629
    [Abstract] [Full Text] [Related]

  • 7. Activation of the trans geometry in platinum antitumor complexes: a survey of the cytotoxicity of trans complexes containing planar ligands in murine L1210 and human tumor panels and studies on their mechanism of action.
    Farrell N, Kelland LR, Roberts JD, Van Beusichem M.
    Cancer Res; 1992 Sep 15; 52(18):5065-72. PubMed ID: 1516063
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and antitumor activity of 1,2-diaminocyclohexane platinum(IV) complexes.
    Khokhar AR, al-Baker S, Siddik ZH.
    J Inorg Biochem; 1994 Apr 15; 54(1):39-47. PubMed ID: 8151310
    [Abstract] [Full Text] [Related]

  • 9. Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines.
    Yoshida M, Khokhar AR, Siddik ZH.
    Cancer Res; 1994 Jul 01; 54(13):3468-73. PubMed ID: 8012968
    [Abstract] [Full Text] [Related]

  • 10. Comparison of cytotoxicity and cellular accumulation of polynuclear platinum complexes in L1210 murine leukemia cell lines.
    Roberts JD, Peroutka J, Beggiolin G, Manzotti C, Piazzoni L, Farrell N.
    J Inorg Biochem; 1999 Oct 01; 77(1-2):47-50. PubMed ID: 10626353
    [Abstract] [Full Text] [Related]

  • 11. Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R,2R-diaminocyclohexane platinum(IV) complexes.
    Siddik ZH, al-Baker S, Thai G, Khokhar AR.
    Anticancer Drug Des; 1994 Apr 01; 9(2):139-51. PubMed ID: 8166929
    [Abstract] [Full Text] [Related]

  • 12. Intraliposomal conversion of lipophilic cis-bis-carboxylato-trans-R,R-1,2-diaminocyclohexane-platinum (II) complexes into cis-bis-dichloro-trans-R,R-1,2-diaminocyclohexane-platinum (II).
    Han I, Khokhar AR, Perez-Soler R.
    Cancer Chemother Pharmacol; 1996 Apr 01; 39(1-2):17-24. PubMed ID: 8995495
    [Abstract] [Full Text] [Related]

  • 13. Differential cytotoxicity, uptake and DNA binding of tetraplatin and analogous isomers in sensitive and resistant cancer cell lines.
    Kido Y, Khokhar AR, Siddik ZH.
    Anticancer Drugs; 1993 Apr 01; 4(2):251-8. PubMed ID: 8490203
    [Abstract] [Full Text] [Related]

  • 14. Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.
    Ali MS, Khan SR, Ojima H, Guzman IY, Whitmire KH, Siddik ZH, Khokhar AR.
    J Inorg Biochem; 2005 Mar 01; 99(3):795-804. PubMed ID: 15708801
    [Abstract] [Full Text] [Related]

  • 15. Chemical and biological studies on a series of lipid-soluble (trans-(R,R)- and -(S,S)-1,2-diaminocyclohexane)platinum(II) complexes incorporated in liposomes.
    Khokhar AR, al-Baker S, Brown T, Perez-Soler R.
    J Med Chem; 1991 Jan 01; 34(1):325-9. PubMed ID: 1992134
    [Abstract] [Full Text] [Related]

  • 16. Inversion of the cis geometry requirement for cytotoxicity in structurally novel platinum(II) complexes containing the bidentate N,O-donor pyridin-2-yl-acetate.
    Bierbach U, Sabat M, Farrell N.
    Inorg Chem; 2000 May 01; 39(9):1882-90. PubMed ID: 11428108
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and in vitro and in vivo antitumor activity of a series of trans platinum antitumor complexes.
    Kelland LR, Barnard CF, Evans IG, Murrer BA, Theobald BR, Wyer SB, Goddard PM, Jones M, Valenti M, Bryant A.
    J Med Chem; 1995 Aug 04; 38(16):3016-24. PubMed ID: 7636864
    [Abstract] [Full Text] [Related]

  • 18. Axial ligands and alicyclic ring size modulate the activity and biochemical pharmacology of ammine/cycloalkylamine-platinum(IV) complexes in tumor cells resistant to cis-diamminedichloroplatinum(II) or trans-1R,2R-1S,2S-diaminocyclohexanetetrachloroplatinum(IV).
    Yoshida M, Khokhar AR, Siddik ZH.
    Cancer Res; 1994 Sep 01; 54(17):4691-7. PubMed ID: 8062266
    [Abstract] [Full Text] [Related]

  • 19. Toxicity and antitumor activity of cis-bis-carboxylato(trans-R,R-1,2-diaminocyclohexane) platinum(II) complexes entrapped in liposomes.
    Khokhar AR, al-Baker S, Krakoff IH, Perez-Soler R.
    Cancer Chemother Pharmacol; 1989 Sep 01; 23(4):219-24. PubMed ID: 2647311
    [Abstract] [Full Text] [Related]

  • 20. Antitumor activity and cross-resistance studies with Pt-ascorbato complexes.
    Hrubisko M, Balázová E, Kiss F, Kovácová J, Ujházy V.
    Neoplasma; 1989 Sep 01; 36(6):651-7. PubMed ID: 2615869
    [Abstract] [Full Text] [Related]

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