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Journal Abstract Search

175 related items for PubMed ID: 23747843

  • 1. Application of exogenous mixture of glutathione and stable isotope labeled glutathione for trapping reactive metabolites in cryopreserved human hepatocytes. Detection of the glutathione conjugates using high resolution accurate mass spectrometry.
    Mezine I, Bode C, Raughley B, Bhoopathy S, Roberts KJ, Owen AJ, Hidalgo IJ.
    Chem Biol Interact; 2013 Aug 25; 204(3):173-84. PubMed ID: 23747843
    [Abstract] [Full Text] [Related]

  • 2. A generic method to detect electrophilic intermediates using isotopic pattern triggered data-dependent high-resolution accurate mass spectrometry.
    Lim HK, Chen J, Cook K, Sensenhauser C, Silva J, Evans DC.
    Rapid Commun Mass Spectrom; 2008 Apr 25; 22(8):1295-311. PubMed ID: 18383206
    [Abstract] [Full Text] [Related]

  • 3. Unbiased high-throughput screening of reactive metabolites on the linear ion trap mass spectrometer using polarity switch and mass tag triggered data-dependent acquisition.
    Yan Z, Caldwell GW, Maher N.
    Anal Chem; 2008 Aug 15; 80(16):6410-22. PubMed ID: 18642850
    [Abstract] [Full Text] [Related]

  • 4. Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer.
    Wang Z, Fang Y, Rock D, Ma J.
    Anal Bioanal Chem; 2018 Feb 15; 410(5):1595-1606. PubMed ID: 29256080
    [Abstract] [Full Text] [Related]

  • 5. Stable-isotope trapping and high-throughput screenings of reactive metabolites using the isotope MS signature.
    Yan Z, Caldwell GW.
    Anal Chem; 2004 Dec 01; 76(23):6835-47. PubMed ID: 15571331
    [Abstract] [Full Text] [Related]

  • 6. Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites.
    Yamaoka T, Kitamura Y.
    J Pharmacol Toxicol Methods; 2015 Dec 01; 76():83-95. PubMed ID: 26314789
    [Abstract] [Full Text] [Related]

  • 7. Improved detection of reactive metabolites with a bromine-containing glutathione analog using mass defect and isotope pattern matching.
    Leblanc A, Shiao TC, Roy R, Sleno L.
    Rapid Commun Mass Spectrom; 2010 May 15; 24(9):1241-50. PubMed ID: 20391594
    [Abstract] [Full Text] [Related]

  • 8. Enhanced screening of glutathione-trapped reactive metabolites by in-source collision-induced dissociation and extraction of product ion using UHPLC-high resolution mass spectrometry.
    Zhu X, Kalyanaraman N, Subramanian R.
    Anal Chem; 2011 Dec 15; 83(24):9516-23. PubMed ID: 22077671
    [Abstract] [Full Text] [Related]

  • 9. Application of stable isotope labeled glutathione and rapid scanning mass spectrometers in detecting and characterizing reactive metabolites.
    Mutlib A, Lam W, Atherton J, Chen H, Galatsis P, Stolle W.
    Rapid Commun Mass Spectrom; 2005 Dec 15; 19(23):3482-92. PubMed ID: 16261644
    [Abstract] [Full Text] [Related]

  • 10. Involvement of different human glutathione transferase isoforms in the glutathione conjugation of reactive metabolites of troglitazone.
    Okada R, Maeda K, Nishiyama T, Aoyama S, Tozuka Z, Hiratsuka A, Ikeda T, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2011 Dec 15; 39(12):2290-7. PubMed ID: 21914835
    [Abstract] [Full Text] [Related]

  • 11. Rapid screening of glutathione-trapped reactive metabolites by linear ion trap mass spectrometry with isotope pattern-dependent scanning and postacquisition data mining.
    Ma L, Wen B, Ruan Q, Zhu M.
    Chem Res Toxicol; 2008 Jul 15; 21(7):1477-83. PubMed ID: 18549250
    [Abstract] [Full Text] [Related]

  • 12. Metabolism of prazosin in rat, dog, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.
    Erve JC, Vashishtha SC, DeMaio W, Talaat RE.
    Drug Metab Dispos; 2007 Jun 15; 35(6):908-16. PubMed ID: 17353349
    [Abstract] [Full Text] [Related]

  • 13. Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.
    Rousu T, Pelkonen O, Tolonen A.
    Rapid Commun Mass Spectrom; 2009 Mar 15; 23(6):843-55. PubMed ID: 19224530
    [Abstract] [Full Text] [Related]

  • 14. High-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.
    Barbara JE, Castro-Perez JM.
    Rapid Commun Mass Spectrom; 2011 Oct 30; 25(20):3029-40. PubMed ID: 21953957
    [Abstract] [Full Text] [Related]

  • 15. Profiling primaquine metabolites in primary human hepatocytes using UHPLC-QTOF-MS with 13C stable isotope labeling.
    Avula B, Tekwani BL, Chaurasiya ND, Nanayakkara NP, Wang YH, Khan SI, Adelli VR, Sahu R, Elsohly MA, McChesney JD, Khan IA, Walker LA.
    J Mass Spectrom; 2013 Feb 30; 48(2):276-85. PubMed ID: 23378100
    [Abstract] [Full Text] [Related]

  • 16. Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high-resolution mass spectrometry and mass defect filtering.
    Zhu M, Ma L, Zhang H, Humphreys WG.
    Anal Chem; 2007 Nov 01; 79(21):8333-41. PubMed ID: 17918967
    [Abstract] [Full Text] [Related]

  • 17. Methylenedioxy designer drugs: mass spectrometric characterization of their glutathione conjugates by means of liquid chromatography-high-resolution mass spectrometry/mass spectrometry and studies on their glutathionyl transferase inhibition potency.
    Meyer MR, Richter LH, Maurer HH.
    Anal Chim Acta; 2014 Apr 25; 822():37-50. PubMed ID: 24725746
    [Abstract] [Full Text] [Related]

  • 18. Detection of reactive metabolites using isotope-labeled glutathione trapping and simultaneous neutral loss and precursor ion scanning with ultra-high-pressure liquid chromatography triple quadruple mass spectrometry.
    Huang K, Huang L, van Breemen RB.
    Anal Chem; 2015 Apr 07; 87(7):3646-54. PubMed ID: 25774910
    [Abstract] [Full Text] [Related]

  • 19. A semiquantitative method for the determination of reactive metabolite conjugate levels in vitro utilizing liquid chromatography-tandem mass spectrometry and novel quaternary ammonium glutathione analogues.
    Soglia JR, Contillo LG, Kalgutkar AS, Zhao S, Hop CE, Boyd JG, Cole MJ.
    Chem Res Toxicol; 2006 Mar 07; 19(3):480-90. PubMed ID: 16544956
    [Abstract] [Full Text] [Related]

  • 20. Enhanced detection and characterization of glutathione-trapped reactive metabolites by pseudo-MS(3) transition using a linear ion trap mass spectrometer.
    Zhu X, Hayashi M, Subramanian R.
    Chem Res Toxicol; 2012 Sep 17; 25(9):1839-41. PubMed ID: 22920186
    [Abstract] [Full Text] [Related]

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